All Outputs (3)

Postinfective bowel dysfunction following Campylobacter enteritis is characterised by reduced microbiota diversity and impaired microbiota recovery (2022)
Journal Article
Jalanka, J., Gunn, D., Singh, G., Krishnasamy, S., Lingaya, M., Crispie, F., …Spiller, R. C. (2022). Postinfective bowel dysfunction following Campylobacter enteritis is characterised by reduced microbiota diversity and impaired microbiota recovery. Gut, https://doi.org/10.1136/gutjnl-2021-326828

Objectives: Persistent bowel dysfunction following gastroenteritis (postinfectious (PI)-BD) is well recognised, but the associated changes in microbiota remain unclear. Our aim was to define these changes after gastroenteritis caused by a single orga... Read More about Postinfective bowel dysfunction following Campylobacter enteritis is characterised by reduced microbiota diversity and impaired microbiota recovery.

The serotonin receptor 3E variant is a risk factor for female IBS-D (2022)
Journal Article
Fritz, N., Berens, S., Dong, Y., Martínez, C., Schmitteckert, S., Houghton, L. A., …Niesler, B. (2022). The serotonin receptor 3E variant is a risk factor for female IBS-D. Journal of Molecular Medicine, 100, 1617–1627. https://doi.org/10.1007/s00109-022-02244-w

Irritable bowel syndrome (IBS) is a gut-brain disorder of multifactorial origin. Evidence of disturbed serotonergic function in IBS accumulated for the 5-HT3 receptor family. 5-HT3Rs are encoded by HTR3 genes and control GI function, and peristalsis... Read More about The serotonin receptor 3E variant is a risk factor for female IBS-D.

Application of In Vivo MRI Imaging to Track a Coated Capsule and Its Disintegration in the Gastrointestinal Tract in Human Volunteers (2022)
Journal Article
Sulaiman, S., Gershkovich, P., Hoad, C. L., Calladine, M., Spiller, R. C., Stolnik, S., & Marciani, L. (2022). Application of In Vivo MRI Imaging to Track a Coated Capsule and Its Disintegration in the Gastrointestinal Tract in Human Volunteers. Pharmaceutics, 14(2), Article 270. https://doi.org/10.3390/pharmaceutics14020270

Oral specially coated formulations have the potential to improve treatment outcomes of a range of diseases in distal intestinal tract whilst limiting systemic drug absorption and adverse effects. Their development is challenging, partly because of li... Read More about Application of In Vivo MRI Imaging to Track a Coated Capsule and Its Disintegration in the Gastrointestinal Tract in Human Volunteers.