Environmental chemicals impact dog semen quality in vitro and may be associated with a temporal decline in sperm motility and increased cryptorchidism

Lea, Richard G.; Byers, Andrew S.; Sumner, Rebecca N.; Rhind, Stewart M.; Zhang, Zulin; Freeman, Sarah L.; Moxon, Rachel; Richardson, Holly M.; Green, Martin; Craigon, Jim; England, Gary C.W.

doi:10.1038/srep31281

All Outputs (5)

Temporal trends in equine sperm progressive motility: a systematic review and meta-regression (2023)
Journal Article

In brief: Adverse trends in reproductive function are a concern in humans, companion, livestock, and wildlife species. This study indicates that equine populations are at risk of a comparable decline in sperm progressive motility. Abstract: There is... Read More about Temporal trends in equine sperm progressive motility: a systematic review and meta-regression.

Systematic Analysis of Breed, Methodological, and Geographical Impact on Equine Sperm Progressive Motility (2021)
Journal Article

Over the past five decades, there has been increasing evidence to indicate global declines in human semen quality. Parallel adverse trends measured in male animals indicate a potential environmental aetiology. This study evaluated the progressive mot... Read More about Systematic Analysis of Breed, Methodological, and Geographical Impact on Equine Sperm Progressive Motility.

Environmental chemicals in dog testes reflect their geographical source and may be associated with altered pathology (2021)
Journal Article

In humans and dogs, a temporal decline in semen quality and increased incidence of testicular cancer is hypothesised to be associated with exposure to anthropogenic chemicals, particularly during fetal development. Human studies suggest that differen... Read More about Environmental chemicals in dog testes reflect their geographical source and may be associated with altered pathology.

Independent and combined effects of diethylhexyl phthalate and polychlorinated biphenyl 153 on sperm quality in the human and dog (2019)
Journal Article

A temporal decline in human and dog sperm quality is thought to reflect a common environmental aetiology. This may reflect direct effects of seminal chemicals on sperm function and quality. Here we report the effects of diethylhexyl phthalate (DEHP)... Read More about Independent and combined effects of diethylhexyl phthalate and polychlorinated biphenyl 153 on sperm quality in the human and dog.

Environmental chemicals impact dog semen quality in vitro and may be associated with a temporal decline in sperm motility and increased cryptorchidism (2016)
Journal Article

Adverse temporal trends in human semen quality and cryptorchidism in infants have been associated with exposure to environmental chemicals (ECs) during development. Here we report that a population of breeding dogs exhibit a 26 year (1988–2014) decli... Read More about Environmental chemicals impact dog semen quality in vitro and may be associated with a temporal decline in sperm motility and increased cryptorchidism.