Differential and defective transcription of koala retrovirus indicates the complexity of host and virus evolution

Tarlinton, R. E.; Legione, A. R.; Sarker, N.; Fabijan, J.; Meers, J.; McMichael, L.; Simmons, G.; Owen, H.; Seddon, J .M.; Dick, G.; Ryder, J. S.; Hemmatzedah, F.; Trott, D. J.; Speight, N.; Holmes, N.; Loose, M.; Emes, R. D.

doi:10.1099/jgv.0.001749

All Outputs (3)

Genome Reference Assembly for Bottlenecked Southern Australian Koalas (2022)
Journal Article

Koala populations show marked differences in inbreeding levels and in the presence or absence of the endogenous Koala retrovirus (KoRV). These genetic differences among populations may lead to severe disease impacts threatening koala population viabi... Read More about Genome Reference Assembly for Bottlenecked Southern Australian Koalas.

Paternal low protein diet perturbs inter-generational metabolic homeostasis in a tissue-specific manner in mice (2022)
Journal Article

The underlying mechanisms driving paternally-programmed metabolic disease in offspring remain poorly defined. We fed male C57BL/6 mice either a control normal protein diet (NPD; 18% protein) or an isocaloric low protein diet (LPD; 9% protein) for a m... Read More about Paternal low protein diet perturbs inter-generational metabolic homeostasis in a tissue-specific manner in mice.

Differential and defective transcription of koala retrovirus indicates the complexity of host and virus evolution (2022)
Journal Article

Koala retrovirus (KoRV) is unique amongst endogenous (inherited) retroviruses in that its incorporation to the host genome is still active, providing an opportunity to study what drives this fundamental process in vertebrate genome evolution. Animals... Read More about Differential and defective transcription of koala retrovirus indicates the complexity of host and virus evolution.