Immune-Instructive Polymers Control Macrophage Phenotype and Modulate the Foreign Body Response In Vivo

Rostam, Hassan M.; Fisher, Leanne E.; Hook, Andrew L.; Burroughs, Laurence; Luckett, Jeni C.; Figueredo, Grazziela P.; Mbadugha, Chidimma; Teo, Alvin C.K.; Latif, Arsalan; Kämmerling, Lisa; Day, Mitchell; Lawler, Karen; Barrett, David; Elsheikh, Somaia; Ilyas, Mohammad; Winkler, David A.; Alexander, Morgan R.; Ghaemmaghami, Amir M.

doi:10.1016/j.matt.2020.03.018

All Outputs (3)

Exploiting Generative Design for 3D Printing of Bacterial Biofilm Resistant Composite Devices (2021)
Journal Article

As the understanding of disease grows, so does the opportunity for personalization of therapies targeted to the needs of the individual. To bring about a step change in the personalization of medical devices it is shown that multi-material inkjet-bas... Read More about Exploiting Generative Design for 3D Printing of Bacterial Biofilm Resistant Composite Devices.

Discovery of hemocompatible bacterial biofilm-resistant copolymers (2020)
Journal Article

© 2020 The Authors Blood-contacting medical devices play an important role within healthcare and are required to be biocompatible, hemocompatible and resistant to microbial colonization. Here we describe a high throughput screen for copolymers with t... Read More about Discovery of hemocompatible bacterial biofilm-resistant copolymers.

Immune-Instructive Polymers Control Macrophage Phenotype and Modulate the Foreign Body Response In Vivo (2020)
Journal Article

© 2020 The Author(s) Implantation of medical devices can result in inflammation. A large library of polymers is screened, and a selection found to promote macrophage differentiation towards pro- or anti-inflammatory phenotypes. The bioinstructive pro... Read More about Immune-Instructive Polymers Control Macrophage Phenotype and Modulate the Foreign Body Response In Vivo.