Tumour-draining axillary lymph nodes in patients with large and locally advanced breast cancers undergoing neoadjuvant chemotherapy (NAC): the crucial contribution of immune cells (effector, regulatory) and cytokines (TH1, TH2) to immune-mediated tumour cell death induced by NAC

Kaewkangsadan, Viriya; Verma, Chandan; Eremin, Jennifer M.; Cowley, Gerard P.; Ilyas, Mohammad; Eremin, Oleg

doi:10.1186/s12885-018-4044-z

All Outputs (6)

TGF?1-induced cell motility but not cell proliferation is mediated through Cten in colorectal cancer (2018)
Journal Article

Cten (C-terminal tensin-like) is a member of the tensin protein family found in complex with integrins at focal adhesions. It promotes epithelial?mesenchymal transition (EMT) and cell motility. The precise mechanisms regulating Cten are unknown, alth... Read More about TGF?1-induced cell motility but not cell proliferation is mediated through Cten in colorectal cancer.

FLYWCH1, a novel suppressor of nuclear b-catenin, regulates migration and morphology in colorectal cancer (2018)
Journal Article

© 2018 American Association for Cancer Research. Wnt/b-catenin signaling plays a critical role during development of both normal and malignant colorectal cancer tissues. Phosphorylation of b-catenin protein alters its trafficking and function. Such c... Read More about FLYWCH1, a novel suppressor of nuclear b-catenin, regulates migration and morphology in colorectal cancer.

CD10 inhibits cell motility but expression is associated with advanced stage disease in colorectal cancer (2018)
Journal Article

Introduction CD10 is a cell membrane-bound endopeptidase which is expressed in normal small bowel but not in normal colon. It is aberrantly expressed in a small proportion of colorectal cancers (CRC) and this has been associated with liver metastasi... Read More about CD10 inhibits cell motility but expression is associated with advanced stage disease in colorectal cancer.

N_LyST: a simple and rapid screening test for Lynch Syndrome (2018)
Journal Article

Aims: We sought to use PCR followed by high-resolution melting (HRM) analysis to develop a single closed-tube screening panel to screen for Lynch Syndrome. This comprises tests for microsatellite instability (MSI), MLH1 methylation promoter and BRAF... Read More about N_LyST: a simple and rapid screening test for Lynch Syndrome.

MDM2 expression in the progression of Barrett’s oesophagus (2018)
Journal Article

Barrett's oesophagus (BO) is the main precursor for oesophageal adenocarcinoma (OAC), and dysplasia arising within it is the standard marker used to predict risk of malignant progression. However, dysplasia diagnosis is subject to a significant amoun... Read More about MDM2 expression in the progression of Barrett’s oesophagus.

Tumour-draining axillary lymph nodes in patients with large and locally advanced breast cancers undergoing neoadjuvant chemotherapy (NAC): the crucial contribution of immune cells (effector, regulatory) and cytokines (TH1, TH2) to immune-mediated tumour cell death induced by NAC (2018)
Journal Article

Background The tumour microenvironment consists of malignant cells, stroma and immune cells. In women with large and locally advanced breast cancers (LLABCs) undergoing neoadjuvant chemotherapy (NAC), tumour-infiltrating lymphocytes (TILs), variou... Read More about Tumour-draining axillary lymph nodes in patients with large and locally advanced breast cancers undergoing neoadjuvant chemotherapy (NAC): the crucial contribution of immune cells (effector, regulatory) and cytokines (TH1, TH2) to immune-mediated tumour cell death induced by NAC.