All Outputs (4)

The DSF family of quorum sensing signals: diversity, biosynthesis, and turnover (2016)
Journal Article
Zhou, L., Zhang, L., Cámara, M., & He, Y. (2017). The DSF family of quorum sensing signals: diversity, biosynthesis, and turnover. Trends in Microbiology, 25(4), https://doi.org/10.1016/j.tim.2016.11.013

The diffusible signaling factor (DSF)-based quorum sensing (QS) system has emerged as a widely conserved cell–cell communication mechanism in Gram-negative bacteria. Typically, signals from the DSF family are cis-2-unsaturated fatty acids which regul... Read More about The DSF family of quorum sensing signals: diversity, biosynthesis, and turnover.

Unravelling the Genome-Wide Contributions of Specific 2-Alkyl-4-Quinolones and PqsE to Quorum Sensing in Pseudomonas aeruginosa (2016)
Journal Article
Rampioni, G., Falcone, M., Heeb, S., Frangipani, E., Fletcher, M. P., Dubern, J., …Williams, P. (2016). Unravelling the Genome-Wide Contributions of Specific 2-Alkyl-4-Quinolones and PqsE to Quorum Sensing in Pseudomonas aeruginosa. PLoS Pathogens, 12(11), e1006029. https://doi.org/10.1371/journal.ppat.1006029

The pqs quorum sensing (QS) system is crucial for Pseudomonas aeruginosa virulence both in vitro and in animal models of infection and is considered an ideal target for the development of anti-virulence agents. However, the precise role played by eac... Read More about Unravelling the Genome-Wide Contributions of Specific 2-Alkyl-4-Quinolones and PqsE to Quorum Sensing in Pseudomonas aeruginosa.

Diagnostic and prognostic significance of systemic alkyl quinolones for P. aeruginosa in cystic fibrosis: a longitudinal study (2016)
Journal Article
Barr, H. L., Halliday, N., Barrett, D. A., Williams, P., Forrester, D. L., Peckham, D., …Fogarty, A. W. (2017). Diagnostic and prognostic significance of systemic alkyl quinolones for P. aeruginosa in cystic fibrosis: a longitudinal study. Journal of Cystic Fibrosis, 16(2), 230-238. https://doi.org/10.1016/j.jcf.2016.10.005

Background Pulmonary P. aeruginosa infection is associated with poor outcomes in cystic fibrosis (CF) and early diagnosis is challenging, particularly in those who are unable to expectorate sputum. Specific P. aeruginosa 2-alkyl-4-quinolones are det... Read More about Diagnostic and prognostic significance of systemic alkyl quinolones for P. aeruginosa in cystic fibrosis: a longitudinal study.

Immune dysfunction in patients with obstructive jaundice before and after endoscopic retrograde cholangiopancreatography (2016)
Journal Article
Chowdhury, A. H., Camara, M., Martinez-Pomares, L., Zaitoun, A. M., Eremin, O., Aithal, G. P., & Lobo, D. (2016). Immune dysfunction in patients with obstructive jaundice before and after endoscopic retrograde cholangiopancreatography. Clinical Science, 130(17), 1535-1544. https://doi.org/10.1042/CS20160326

© 2016 The Author(s). This prospective observational study investigated monocyte cytokine responses to lipopolysaccharide (LPS) in patients with obstructive jaundice (OJ) before and after endoscopic biliary drainage. Dendritic cell (DC) subsets and t... Read More about Immune dysfunction in patients with obstructive jaundice before and after endoscopic retrograde cholangiopancreatography.