Detection and quantification of allosteric modulation of endogenous M4 muscarinic acetylcholine receptor using impedance-based label-free technology in a neuronal cell line
(2014)
Journal Article
Chen, A. N., Chen, A., Malone, D. T., Pabreja, K., Sexton, P. M., Christopoulos, A., & Canals, M. (2014). Detection and quantification of allosteric modulation of endogenous M4 muscarinic acetylcholine receptor using impedance-based label-free technology in a neuronal cell line. Journal of Biomolecular Screening, 20(5), 646-654. https://doi.org/10.1177/1087057114563025
© 2014 Society for Laboratory Automation and Screening. Allosteric modulators of G protein-coupled receptors have the potential to achieve greater receptor subtype selectivity compared with ligands targeting the orthosteric site of this receptor fami... Read More about Detection and quantification of allosteric modulation of endogenous M4 muscarinic acetylcholine receptor using impedance-based label-free technology in a neuronal cell line.