All Outputs (13)

Evaluating the effect of maternal non-communicable disease on adverse pregnancy outcomes and birthweight in Pakistan, a facility based retrospective cohort study (2024)
Journal Article

Background: Non-communicable diseases (NCDs) claim 74% of global lives, disproportionately affecting lower and middle-income countries like Pakistan. NCDs may increase the risk of preterm birth (PTB), caesarean section (CS), and low birthweight. This... Read More about Evaluating the effect of maternal non-communicable disease on adverse pregnancy outcomes and birthweight in Pakistan, a facility based retrospective cohort study.

Evaluating the effect of maternal non-communicable disease on adverse pregnancy outcomes and birthweight in Pakistan, a facility based retrospective cohort study (2024)
Journal Article

Non-communicable diseases (NCDs) claim 74% of global lives, disproportionately affecting lower and middle-income countries like Pakistan. NCDs may increase the risk of preterm birth (PTB), caesarean section (CS), and low birthweight. This study aims... Read More about Evaluating the effect of maternal non-communicable disease on adverse pregnancy outcomes and birthweight in Pakistan, a facility based retrospective cohort study.

The impact of maternal obesity on in vivo uterine contractile activity during parturition in the rat (2023)
Journal Article

Maternal obesity is associated with increased risk of prolonged and dysfunctional labor and emergency caesarean section. To elucidate the mechanisms behind the associated uterine dystocia, a translational animal model is required. Our previous work i... Read More about The impact of maternal obesity on in vivo uterine contractile activity during parturition in the rat.

98 The effect of mezquite pod flour in a wheat-based diet on broiler chicken growth performance (2021)
Journal Article

Application Inclusion of Mezquite pod flour in broiler chicken diets significantly reduced weight gain, this could inform a recommendation against the use of non-processed Mezquite in broiler chicken diets. Introduction Mezquite is an under-utilised... Read More about 98 The effect of mezquite pod flour in a wheat-based diet on broiler chicken growth performance.

Acute changes to breast milk composition following consumption of high-fat and high-sugar meals (2021)
Journal Article

© 2021 The Authors. Maternal & Child Nutrition published by John Wiley & Sons Ltd. Breast milk composition is influenced by habitual diet, yet little is known about the short-term effects of changes in maternal diet on breast milk macronutrient c... Read More about Acute changes to breast milk composition following consumption of high-fat and high-sugar meals.

The effect of maternal dietary fat content and omega-6 to omega-3 ratio on offspring growth and hepatic gene expression in the rat (2020)
Journal Article

© The Authors 2020. Omega-6 fatty acids have been shown to exert pro-adipogenic effects whereas omega-3 fatty acids work in opposition. Increasing intakes of LA (linoleic acid; omega-6) vs ALA (alpha-linolenic acid; omega-3) in Western diets has led... Read More about The effect of maternal dietary fat content and omega-6 to omega-3 ratio on offspring growth and hepatic gene expression in the rat.

The impact of exposure to cafeteria diet during pregnancy or lactation on offspring growth and adiposity before weaning (2019)
Journal Article

Exposure to maternal obesity during early-life can have adverse consequences for offspring growth and adiposity. We aimed to assess the relative contributions of exposure to maternal obesity, induced by a highly varied cafeteria diet, during pregnanc... Read More about The impact of exposure to cafeteria diet during pregnancy or lactation on offspring growth and adiposity before weaning.

Exposure to maternal obesity during suckling outweighs in utero exposure in programming for post-weaning adiposity and insulin resistance in rats (2019)
Journal Article

Exposure to maternal obesity during early development programmes adverse metabolic health in rodent offspring. We assessed the relative contributions of obesity during pregnancy and suckling on metabolic health post-weaning. Wistar rat offspring expo... Read More about Exposure to maternal obesity during suckling outweighs in utero exposure in programming for post-weaning adiposity and insulin resistance in rats.

Maternal dietary ratio of linoleic acid to alpha-linolenic acid during pregnancy has sexspecific effects on placental and fetal weights in the rat (2019)
Journal Article

Background: Increased consumption of linoleic acid (LA, omega-6) in Western diets coupled with the pro-inflammatory and adipogenic properties of its derivatives has led to suggestions that fetal exposure to this dietary pattern could be contributing... Read More about Maternal dietary ratio of linoleic acid to alpha-linolenic acid during pregnancy has sexspecific effects on placental and fetal weights in the rat.

Maternal obesity-induced decreases in plasma, hepatic and uterine polyunsaturated fatty acids during labour is reversed through improved nutrition at conception (2018)
Journal Article

Maternal obesity is associated with prolonged and dysfunctional labour, potentially through decreased synthesis of prostaglandins that stimulate myometrial contractions. We assessed the impact of maternal obesity on concentrations of precursor fatty... Read More about Maternal obesity-induced decreases in plasma, hepatic and uterine polyunsaturated fatty acids during labour is reversed through improved nutrition at conception.

Modelling maternal obesity: the effects of a chronic high-fat, high-cholesterol diet on uterine expression of contractile-associated proteins and ex vivo contractile activity during labour in the rat (2015)
Journal Article

Maternal obesity is associated with prolonged and dysfunctional labour and emergency caesarean section, but the mechanisms are unknown. The present study investigated the effects of an adiposity-inducing high fat, high-cholesterol (HFHC) diet on uter... Read More about Modelling maternal obesity: the effects of a chronic high-fat, high-cholesterol diet on uterine expression of contractile-associated proteins and ex vivo contractile activity during labour in the rat.

Excess maternal salt or fructose intake programmes sex-specific, stress- and fructose-sensitive hypertension in the offspring (2015)
Journal Article

© Copyright 2015 The Authors. The Western diet is typically high in salt and fructose, which have pressor activity. Maternal diet can affect offspring blood pressure, but the extent to which maternal intake of excess salt and fructose may influence c... Read More about Excess maternal salt or fructose intake programmes sex-specific, stress- and fructose-sensitive hypertension in the offspring.

Maternal age effects on myometrial expression of contractile proteins, uterine gene expression, and contractile activity during labor in the rat (2015)
Journal Article

Advanced maternal age of first time pregnant mothers is associated with prolonged and dysfunctional labor and significant risk of emergency cesarean section. We investigated the influence of maternal age on myometrial contractility, expression of con... Read More about Maternal age effects on myometrial expression of contractile proteins, uterine gene expression, and contractile activity during labor in the rat.