All Outputs (3)

Maladaptive striatal plasticity and abnormal reward?learning in cervical dystonia (2019)
Journal Article
Gilbertson, T., Humphries, M., & Steele, J. D. (2019). Maladaptive striatal plasticity and abnormal reward?learning in cervical dystonia. European Journal of Neuroscience, 50(7), 3191-3204. https://doi.org/10.1111/ejn.14414

In monogenetic generalized forms of dystonia, in vitro neurophysiological recordings have demonstrated direct evidence for abnormal plasticity at the level of the cortico?striatal synapse. It is unclear whether similar abnormalities contribute to the... Read More about Maladaptive striatal plasticity and abnormal reward?learning in cervical dystonia.

Prediction of Choice from Competing Mechanosensory and Choice-Memory Cues during Active Tactile Decision Making (2019)
Journal Article
Campagner, D., Evans, M. H., Chlebikova, K., Colins-Rodriguez, A., Loft, M. S., Fox, S., …Petersen, R. S. (2019). Prediction of Choice from Competing Mechanosensory and Choice-Memory Cues during Active Tactile Decision Making. Journal of Neuroscience, 39(20), 3921-3933. https://doi.org/10.1523/jneurosci.2217-18.2019

Perceptual decision making is an active process where animals move their sense organs to extract task-relevant information. To investigate how the brain translates sensory input into decisions during active sensation, we developed a mouse active touc... Read More about Prediction of Choice from Competing Mechanosensory and Choice-Memory Cues during Active Tactile Decision Making.

Medial prefrontal cortex population activity is plastic irrespective of learning (2019)
Journal Article
Singh, A., Peyrache, A., & Humphries, M. D. (2019). Medial prefrontal cortex population activity is plastic irrespective of learning. Journal of Neuroscience, 39(18), 3470-3483. https://doi.org/10.1523/JNEUROSCI.1370-17.2019

The prefrontal cortex is thought to learn the relationships between actions and their outcomes. But little is known about what changes to population activity in prefrontal cortex are specific to learning these relationships. Here we characterise the... Read More about Medial prefrontal cortex population activity is plastic irrespective of learning.