All Outputs (9)

Immunohistochemical Investigation into Protein Expression Patterns of FOXO4, IRF8 and LEF1 in Canine Osteosarcoma (2024)
Journal Article

Osteosarcoma (OSA) is the most common type of primary bone malignancy in people and dogs. Our previous molecular comparisons of canine OSA against healthy bone resulted in the identification of differentially expressed protein-expressing genes (forkh... Read More about Immunohistochemical Investigation into Protein Expression Patterns of FOXO4, IRF8 and LEF1 in Canine Osteosarcoma.

Immunohistochemical Characterisation of GLUT1, MMP3 and NRF2 in Osteosarcoma (2021)
Journal Article

Osteosarcoma (OSA) is an aggressive bone malignancy. Unlike many other malignancies, OSA outcomes have not improved in recent decades. One challenge to the development of better diagnostic and therapeutic methods for OSA has been the lack of well cha... Read More about Immunohistochemical Characterisation of GLUT1, MMP3 and NRF2 in Osteosarcoma.

Molecular characterisation of canine osteosarcoma in high risk breeds (2020)
Journal Article

© 2020 by the authors. Licensee MDPI, Basel, Switzerland. Dogs develop osteosarcoma (OSA) and the disease process closely resembles that of human OSA. OSA has a poor prognosis in both species and disease-free intervals and cure rates have not improve... Read More about Molecular characterisation of canine osteosarcoma in high risk breeds.

Survey-based pilot study into the chosen therapy and prophylaxis used by UK primary care veterinary surgeons against canine angiostrongylosis (2018)
Journal Article

Canine Angiostrongylosis (CA), a gastropod-borne parasitic infection caused by the metastrongyloid nematode Angiostrongylus vasorum, is an important cause of significant morbidity to domestic dogs across the UK as well as in other European countries.... Read More about Survey-based pilot study into the chosen therapy and prophylaxis used by UK primary care veterinary surgeons against canine angiostrongylosis.

Pathological findings in the pituitary glands of 201 dogs and cats (2018)
Journal Article

With the exception of classic functional adenomas in dogs and horses, pituitary lesions are infrequently described in the veterinary literature. Approximately 10% of pituitary glands from asymptomatic humans contain abnormalities but the equivalent p... Read More about Pathological findings in the pituitary glands of 201 dogs and cats.

Comparative review of human and canine osteosarcoma: morphology, epidemiology, prognosis, treatment and genetics (2017)
Journal Article

Osteosarcoma (OSA) is a rare cancer in people. However OSA incidence rates in dogs are 27 times higher than in people. Prognosis in both species is poor, with five year osteosarcoma survival rates in people not having improved in decades. For dogs, o... Read More about Comparative review of human and canine osteosarcoma: morphology, epidemiology, prognosis, treatment and genetics.

Preliminary investigation of urine N-telopeptide concentration as a biomarker of bone resorption in dogs receiving glucocorticoids: Urinary NTx in glucocorticoid treated dogs (2017)
Journal Article

Objectives The influence of glucocorticoid therapy on bone resorption in dogs using a urine N?telopeptide assay was investigated. Materials and Methods Thirty?one dogs receiving oral glucocorticoids and 31 age?matched healthy control dogs were e... Read More about Preliminary investigation of urine N-telopeptide concentration as a biomarker of bone resorption in dogs receiving glucocorticoids: Urinary NTx in glucocorticoid treated dogs.

Improving IBD in dogs through exercise (2017)
Journal Article

Multiple genetic associations with Irish wolfhound dilated cardiomyopathy (2016)
Journal Article

Cardiac disease is a leading cause of morbidity and mortality in dogs and humans, with dilated cardiomyopathy being a large contributor to this. The Irish Wolfhound (IWH) is one of the most commonly affected breeds and one of the few breeds with gene... Read More about Multiple genetic associations with Irish wolfhound dilated cardiomyopathy.