A fungal family of lytic polysaccharide monooxygenase-like copper proteins

Labourel, Aurore; Frandsen, Kristian E. H.; Zhang, Feng; Brouilly, Nicolas; Grisel, Sacha; Haon, Mireille; Ciano, Luisa; Ropartz, David; Fanuel, Mathieu; Martin, Francis; Navarro, David; Rosso, Marie-No�lle; Tandrup, Tobias; Bissaro, Bastien; Johansen, Katja S.; Zerva, Anastasia; Walton, Paul H.; Henrissat, Bernard; Leggio, Leila Lo; Berrin, Jean-Guy

doi:10.1038/s41589-019-0438-8

All Outputs (4)

Mechanistic basis of substrate–O2 coupling within a chitin-active lytic polysaccharide monooxygenase: An integrated NMR/EPR study (2020)
Journal Article

Lytic polysaccharide monooxygenases (LPMOs) have a unique ability to activate molecular oxygen for subsequent oxidative cleavage of glycosidic bonds. To provide insight into the mode of action of these industrially important enzymes, we have performe... Read More about Mechanistic basis of substrate–O2 coupling within a chitin-active lytic polysaccharide monooxygenase: An integrated NMR/EPR study.

Insights from semi-oriented EPR spectroscopy studies into the interaction of lytic polysaccharide monooxygenases with cellulose (2020)
Journal Article

Probing the detailed interaction between lytic polysaccharide monooxygenases (LPMOs) and their polysaccharide substrates is key to revealing further insights into the mechanism of action of this class of enzymes on recalcitrant biomass. This investig... Read More about Insights from semi-oriented EPR spectroscopy studies into the interaction of lytic polysaccharide monooxygenases with cellulose.

Discovery of a fungal copper radical oxidase with high catalytic efficiency towards 5-hydroxymethylfurfural and benzyl alcohols for bioprocessing (2020)
Journal Article

Copyright © 2020 American Chemical Society. Alternatives to petroleum-based chemicals are highly sought-after for ongoing efforts to reduce the damaging effects of human activity on the environment. Copper radical oxidases from Auxiliary Activity Fam... Read More about Discovery of a fungal copper radical oxidase with high catalytic efficiency towards 5-hydroxymethylfurfural and benzyl alcohols for bioprocessing.

A fungal family of lytic polysaccharide monooxygenase-like copper proteins (2020)
Journal Article

Lytic polysaccharide monooxygenases (LPMOs) are copper-containing enzymes that play a key role in the oxidative degradation of various biopolymers such as cellulose and chitin. While hunting for new LPMOs, we identified in various fungal lineages... Read More about A fungal family of lytic polysaccharide monooxygenase-like copper proteins.