Placental expression of adenosine A2A receptor and hypoxia inducible factor-1 alpha in early pregnancy, term and pre-eclamptic pregnancies: interactions with placental renin-angiotensin system

Kurlak, L.O.; Williams, Paula Juliet; Bulmer, Judith N.; Broughton Pipkin, Fiona; Mistry, Hiten D.

doi:10.1016/j.placenta.2015.02.011

Research Repository

All Outputs (2)

Born from pre-eclamptic pregnancies predisposes infants to altered cortisol metabolism in the first postnatal year (2015)
Journal Article

Pre-eclampsia leads to disturbed fetal organ development, including metabolic syndrome, attributed to altered pituitary-adrenal feedback loop. We measured cortisol metabolites in infants born from pre-eclamptic and normotensive women and hypothesised... Read More about Born from pre-eclamptic pregnancies predisposes infants to altered cortisol metabolism in the first postnatal year.

Placental expression of adenosine A2A receptor and hypoxia inducible factor-1 alpha in early pregnancy, term and pre-eclamptic pregnancies: interactions with placental renin-angiotensin system (2015)
Journal Article

Normal placentation occurs under low oxygen tensions yet hypoxia is also implicated in placental pathologies such as pre-eclampsia (PE). Hypoxia-inducible factors (HIFs), adenosine and tissue renin-angiotensin-system (RAS) are known to promote angiog... Read More about Placental expression of adenosine A2A receptor and hypoxia inducible factor-1 alpha in early pregnancy, term and pre-eclamptic pregnancies: interactions with placental renin-angiotensin system.