A new view of macula densa cell microanatomy

Gyarmati, Georgina; Shroff, Urvi Nikhil; Riquier-Brison, Anne; Kriz, Wilhelm; Kaissling, Brigitte; Neal, Christopher R.; Arkill, Kenton P.; Ahmadi, Nariman; Gill, Inderbir S.; Moon, Ju-Young; Desposito, Dorinne; Peti-Peterdi, J�nos

doi:10.1152/ajprenal.00546.2020

All Outputs (3)

Transcriptomic Analysis of Cardiomyocyte Extracellular Vesicles in Hypertrophic Cardiomyopathy Reveals Differential snoRNA Cargo (2021)
Journal Article
James, V., Nizamudeen, Z. A., Lea, D., Dottorini, T., Holmes, T. L., Johnson, B. B., …Smith, J. G. (2021). Transcriptomic Analysis of Cardiomyocyte Extracellular Vesicles in Hypertrophic Cardiomyopathy Reveals Differential snoRNA Cargo. Stem Cells and Development, 30(24), 1215-1227. https://doi.org/10.1089/scd.2021.0202

Hypertrophic cardiomyopathy (HCM) is characterised by increased left ventricular wall thickness that can lead to devastating conditions such as heart failure and sudden cardiac death. Despite extensive study, the mechanisms mediating many of the asso... Read More about Transcriptomic Analysis of Cardiomyocyte Extracellular Vesicles in Hypertrophic Cardiomyopathy Reveals Differential snoRNA Cargo.

A Reinterpretation of Evidence for the Endothelial Glycocalyx Filtration Structure (2021)
Journal Article
Arkill, K. P. (2021). A Reinterpretation of Evidence for the Endothelial Glycocalyx Filtration Structure. Frontiers in Cell and Developmental Biology, 9, Article 734661. https://doi.org/10.3389/fcell.2021.734661

The endothelial glycocalyx is thought to be the primary macromolecular filter for fluid flux out of the vasculature. This filter maintains the higher protein concentration within the vessel lumen relative to the tissue. Whilst the arguments for the e... Read More about A Reinterpretation of Evidence for the Endothelial Glycocalyx Filtration Structure.

A new view of macula densa cell microanatomy (2021)
Journal Article
Gyarmati, G., Shroff, U. N., Riquier-Brison, A., Kriz, W., Kaissling, B., Neal, C. R., …Peti-Peterdi, J. (2021). A new view of macula densa cell microanatomy. AJP - Renal Physiology, 320(3), F492-F504. https://doi.org/10.1152/ajprenal.00546.2020

Although macula densa (MD) cells are chief regulatory cells in the nephron with unique microanatomical features, they have been difficult to study in full detail due to their inaccessibility and limitations in earlier microscopy techniques. The prese... Read More about A new view of macula densa cell microanatomy.