All Outputs (11)
Synchronous deficits in cumulative muscle protein synthesis and ribosomal biogenesis underlie age-related anabolic resistance to exercise in humans (2016)
Journal Article
Ageing is associated with impaired hypertrophic responses to resistance exercise training (RET). Here we investigated the aetiology of ‘anabolic resistance’ in older humans. Twenty healthy male individuals, 10 younger (Y; 23 ± 1 years) and 10 older (... Read More about Synchronous deficits in cumulative muscle protein synthesis and ribosomal biogenesis underlie age-related anabolic resistance to exercise in humans.
Skype™: a platform for remote, interactive skills instruction (2016)
Journal Article
Supplementing essential amino acids with the nitric oxide precursor, l-arginine, enhances skeletal muscle perfusion without impacting anabolism in older men (2016)
Journal Article
Postprandial limb blood flow and skeletal muscle microvascular perfusion reduce with aging. Here we tested the impact of providing bolus essential amino acids (EAA) in the presence and absence of the nitric oxide precursor, l-Arginine (ARG), upon ske... Read More about Supplementing essential amino acids with the nitric oxide precursor, l-arginine, enhances skeletal muscle perfusion without impacting anabolism in older men.
Simulation fails to replicate stress in trainees performing a technical procedure in the clinical environment (2016)
Journal Article
Introduction: Simulation-based training (SBT) has become an increasingly important method by which doctors learn. Stress has an impact upon learning, performance, technical, and non-technical skills. However, there are currently no studies that compa... Read More about Simulation fails to replicate stress in trainees performing a technical procedure in the clinical environment.
Oleoylethanolamine and palmitoylethanolamine modulate intestinal permeability in vitro via TRPV1 and PPAR? (2016)
Journal Article
Cannabinoids modulate intestinal permeability through cannabinoid receptor 1 (CB1). The endocannabinoid-like compounds oleoylethanolamine (OEA) and palmitoylethanolamine (PEA) play an important role in digestive regulation, and we hypothesized they w... Read More about Oleoylethanolamine and palmitoylethanolamine modulate intestinal permeability in vitro via TRPV1 and PPAR?.
Human Skeletal Muscle Protein Metabolism Responses to Amino Acid Nutrition (2016)
Journal Article
Healthy individuals maintain remarkably constant skeletal muscle mass across much of adult life, suggesting the existence of robust homeostatic mechanisms. Muscle exists in dynamic equilibrium whereby the influx of amino acids (AAs) and the resulting... Read More about Human Skeletal Muscle Protein Metabolism Responses to Amino Acid Nutrition.
Gabapentin for the hemodynamic response to intubation: systematic review and meta-analysis (2016)
Journal Article
Purpose Endotracheal intubation is the gold standard for securing the airway before surgery. Nevertheless, this procedure can produce an activation of the sympathetic nervous system and result in a hemodynamic response which, in high-risk patients... Read More about Gabapentin for the hemodynamic response to intubation: systematic review and meta-analysis.
Mortality of emergency abdominal surgery in high-, middle- and low-income countries (2016)
Journal Article
Background: Surgical mortality data are collected routinely in high-income countries, yet virtually no low- or middle-income countries have outcome surveillance in place. The aim was prospectively to collect worldwide mortality data following emergen... Read More about Mortality of emergency abdominal surgery in high-, middle- and low-income countries.
A 31-day time to surgery compliant exercise training programme improves aerobic health in the elderly (2016)
Journal Article
Background: Over 41,000 people were diagnosed with colorectal cancer (CRC) in the UK in 2011. The incidence of CRC increases with age. Many elderly patients undergo surgery for CRC, the only curative treatment. Such patients are exposed to risks, whi... Read More about A 31-day time to surgery compliant exercise training programme improves aerobic health in the elderly.
Anaesthetists stress is induced by patient ASA grade and may impair non-technical skills during intubation (2016)
Journal Article
Background The aims of this study were to determine if patient ASA grade was associated with increased stress in anaesthetists with a subsequent effect on non-technical skills. Methods Stress was measured using a validated objective (heart rat... Read More about Anaesthetists stress is induced by patient ASA grade and may impair non-technical skills during intubation.