Effect of sodium 4-phenylbutyrate on clenbuterol-mediated muscle growth

Brown, David M.; Jones, Sarah; Daniel, Zoe C.T.R.; Brearley, Madelaine C.; Lewis, Jo E.; Ebling, Francis J.P.; Parr, Tim; Brameld, John M.

doi:10.1371/journal.pone.0201481

All Outputs (3)

Productivity framework (2018)
Journal Article

Researchers look at skills shortages and careers pathways in the agrifood industry. Sustaining the agriculture, food and drink industries requires human capital. Current estimates calculate that the agrifood supply chain employs approaching 4m people... Read More about Productivity framework.

The beta-adrenergic agonist, Ractopamine increases skeletal muscle expression of Asparagine Synthetase as part of an integrated stress response gene program (2018)
Journal Article

Synthetic beta-adrenergic agonists (BA) have broad biomedical and agricultural application for increasing lean body mass, yet a poor understanding of the biology underpinning these agents is limiting further drug discovery potential. Growing female p... Read More about The beta-adrenergic agonist, Ractopamine increases skeletal muscle expression of Asparagine Synthetase as part of an integrated stress response gene program.

Effect of sodium 4-phenylbutyrate on clenbuterol-mediated muscle growth (2018)
Journal Article

Previously, we highlighted induction of an integrated stress response (ISR) gene program in skeletal muscle of pigs treated with a beta-adrenergic agonist. Hence we tested the hypothesis that the ER-stress inhibitor, sodium 4-phenylbutyrate (PBA), wo... Read More about Effect of sodium 4-phenylbutyrate on clenbuterol-mediated muscle growth.