Reduced adiposity attenuates FGF21 mediated metabolic improvements in the Siberian hamster

Lewis, Jo E.; Samms, Ricardo J.; Cooper, Scott; Luckett, Jeni C.; Perkins, Alan C.; Adams, Andrew C.; Tsintzas, Kostas; Ebling, Francis J.P.

doi:10.1038/s41598-017-03607-x

All Outputs (2)

Antibody mediated targeting of the FGFR1c isoform increases glucose uptake in white and brown adipose tissue in male mice (2017)
Journal Article

The increased prevalence of obesity and its cardiometabolic implications demonstrates the imperative to identify novel therapeutic targets able to effect meaningful metabolic changes in this population. Antibody-mediated targeting of fibroblast growt... Read More about Antibody mediated targeting of the FGFR1c isoform increases glucose uptake in white and brown adipose tissue in male mice.

Reduced adiposity attenuates FGF21 mediated metabolic improvements in the Siberian hamster (2017)
Journal Article

FGF21 exerts profound metabolic effects in Siberian hamsters exposed to long day (LD) photoperiods that increase appetite and adiposity, however these effects are attenuated in short day (SD) animals that display hypophagia and reduced adiposity. The... Read More about Reduced adiposity attenuates FGF21 mediated metabolic improvements in the Siberian hamster.