All Outputs (4)

Dopamine D1 receptor involvement in latent inhibition and overshadowing (2012)
Journal Article

Latent inhibition (LI) manifests as poorer conditioning to a stimulus that has previously been experienced without consequence. There is good evidence of dopaminergic modulation of LI, as the e?ect is reliably disrupted by the indirect dopamine (DA... Read More about Dopamine D1 receptor involvement in latent inhibition and overshadowing.

When to hold that thought: an experimental study showing reduced inhibition of pre-trained associations in schizophrenia (2012)
Journal Article

Schizophrenia encompasses a wide variety of cognitive dysfunctions, a number of which can be understood as deficits of inhibition. To date, no research has examined ‘conditioned inhibition’ in schizophrenia - the ability of a stimulus that signals th... Read More about When to hold that thought: an experimental study showing reduced inhibition of pre-trained associations in schizophrenia.

Opposing effects of 5,7-DHT lesions to the core and shell of the nucleus accumbens on the processing of irrelevant stimuli (2012)
Journal Article

There is good evidence that forebrain serotonergic systems modulate cognitive flexibility. Latent inhibition (LI) is a cross-species phenomenon which manifests as poor conditioning to a stimulus that has previously been experienced without consequenc... Read More about Opposing effects of 5,7-DHT lesions to the core and shell of the nucleus accumbens on the processing of irrelevant stimuli.

Dopamine in nucleus accumbens: salience modulation in latent inhibition and overshadowing (2012)
Journal Article

Latent inhibition (LI) is demonstrated when non-reinforced pre-exposure to a to-be-conditioned stimulus retards later learning. Learning is similarly retarded in overshadowing, in this case using the relative intensity of competing cues to manipulate... Read More about Dopamine in nucleus accumbens: salience modulation in latent inhibition and overshadowing.