All Outputs (4)

Location dependent coordination chemistry and MRI relaxivity, in de novo designed lanthanide coiled coils (2015)
Journal Article
Berwick, M. R., Slope, L. N., Smith, C. F., King, S. M., Newton, S. L., Gillis, R. B., …Peacock, A. F. A. (in press). Location dependent coordination chemistry and MRI relaxivity, in de novo designed lanthanide coiled coils. Chemical Science, 7(3), https://doi.org/10.1039/c5sc04101e

Herein, we establish for the first time the design principles for lanthanide coordination within coiled coils, and the important consequences of binding site translation. By interrogating design requirements and by systematically translating binding... Read More about Location dependent coordination chemistry and MRI relaxivity, in de novo designed lanthanide coiled coils.

Application of recent advances in hydrodynamic methods for characterising mucins in solution (2015)
Journal Article
Almutairi, F. M., Cifre, J. H., Adams, G. G., Kök, M. S., Mackie, A. R., de la Torre, J. G., & Harding, S. E. (2016). Application of recent advances in hydrodynamic methods for characterising mucins in solution. European Biophysics Journal, 45(1), 45-54. https://doi.org/10.1007/s00249-015-1075-0

Mucins are the primary macromolecular component of mucus—nature’s natural lubricant—although they are poorly characterised heterogeneous substances. Recent advances in hydrodynamic methodology now offer the opportunity for gaining a better understand... Read More about Application of recent advances in hydrodynamic methods for characterising mucins in solution.

Matrix-free hydrodynamic study on the size distribution and conformation of three technical lignins from wood and non-wood (2015)
Journal Article
Alzahrani, Q. E., Adams, G. G., Gillis, R. B., Besong, T. M., Kök, M. S., Fong, E., …Harding, S. E. (2016). Matrix-free hydrodynamic study on the size distribution and conformation of three technical lignins from wood and non-wood. Holzforschung, 70(2), https://doi.org/10.1515/hf-2014-0318

Molecular weight (MW) and related conformational data of three commercially available technical lignins (Alcell L, kraft L, and soda L) have been studied by means of analytical ultracentrifugation, taking advantage of some recent developments in both... Read More about Matrix-free hydrodynamic study on the size distribution and conformation of three technical lignins from wood and non-wood.

Recent advances in the analysis of macromolecular interactions using the matrix-free method of sedimentation in the analytical ultracentrifuge (2015)
Journal Article
Harding, S., Gillis, R., Almutairi, F., Erten, T., Kök, M., & Adams, G. (2015). Recent advances in the analysis of macromolecular interactions using the matrix-free method of sedimentation in the analytical ultracentrifuge. Biology, 4(1), https://doi.org/10.3390/biology4010237

Sedimentation in the analytical ultracentrifuge is a matrix free solution technique with no immobilisation, columns, or membranes required and can be used to study self-association and complex or “hetero”-interactions, stoichiometry, reversibility an... Read More about Recent advances in the analysis of macromolecular interactions using the matrix-free method of sedimentation in the analytical ultracentrifuge.