All Outputs (5)

Real-time dynamics of Plasmodium NDC80 reveals unusual modes of chromosome segregation during parasite proliferation (2020)
Journal Article
Zeeshan, M., Pandey, R., Ferguson, D. J. P., Tromer, E. C., Markus, R., Abel, S., …Tewari, R. (2020). Real-time dynamics of Plasmodium NDC80 reveals unusual modes of chromosome segregation during parasite proliferation. Journal of Cell Science, 134(5), Article jcs.245753. https://doi.org/10.1242/jcs.245753

Eukaryotic cell proliferation requires chromosome replication and precise segregation to ensure daughter cells have identical genomic copies. The genus Plasmodium, the causative agent of malaria, displays remarkable aspects of nuclear division throug... Read More about Real-time dynamics of Plasmodium NDC80 reveals unusual modes of chromosome segregation during parasite proliferation.

Plasmodium Condensin Core Subunits SMC2/SMC4 Mediate Atypical Mitosis and Are Essential for Parasite Proliferation and Transmission (2020)
Journal Article
Le Roch, K. G., Holder, A. A., Bottrill, A. R., Stanway, R. R., Wall, R. J., Tewari, R., …Brady, D. (2020). Plasmodium Condensin Core Subunits SMC2/SMC4 Mediate Atypical Mitosis and Are Essential for Parasite Proliferation and Transmission. Cell Reports, 30(6), 1883-1897.e6. https://doi.org/10.1016/j.celrep.2020.01.033

Condensin is a multi-subunit protein complex regulating chromosome condensation and segregation during cell division. In Plasmodium spp., the causative agent of malaria, cell division is atypical and the role of condensin is unclear. Here we examine... Read More about Plasmodium Condensin Core Subunits SMC2/SMC4 Mediate Atypical Mitosis and Are Essential for Parasite Proliferation and Transmission.

Plasmodium kinesin-8X associates with mitotic spindles and is essential for oocyst development during parasite proliferation and transmission (2019)
Journal Article
Zeeshan, M., Shilliday, F., Liu, T., Abel, S., Mourier, T., Ferguson, D. J. P., Rea, E., Stanway, R. R., Roques, M., Williams, D., Daniel, E., Brady, D., Roberts, A. J., Holder, A. A., Pain, A., Le, K. G., Le Roch, R. G., Moores, C. A., & Tewari, R. (2019). Plasmodium kinesin-8X associates with mitotic spindles and is essential for oocyst development during parasite proliferation and transmission. PLoS Pathogens, 15(10), Article e1008048. https://doi.org/10.1371/journal.ppat.1008048

Kinesin-8 proteins are microtubule motors that are often involved in regulation of mitotic spindle length and chromosome alignment. They move towards the plus ends of spindle microtubules and regulate the dynamics of these ends due, at least in some... Read More about Plasmodium kinesin-8X associates with mitotic spindles and is essential for oocyst development during parasite proliferation and transmission.

Kinesin-8B controls basal body function and flagellum formation and is key to malaria transmission (2019)
Journal Article
Zeeshan, M., Ferguson, D. J., Abel, S., Burrrell, A., Rea, E., Brady, D., …Tewari, R. (2019). Kinesin-8B controls basal body function and flagellum formation and is key to malaria transmission. Life Science Alliance, 2(4), 1-13. https://doi.org/10.26508/lsa.201900488

Eukaryotic flagella are conserved microtubule-based organelles that drive cell motility. Plasmodium, the causative agent of malaria, has a single flagellate stage: the male gamete in the mosquito. Three rounds of endomitotic division in male gametocy... Read More about Kinesin-8B controls basal body function and flagellum formation and is key to malaria transmission.

Impacts of forestry planting on primary production in upland lakes from north-west Ireland (2016)
Journal Article
Stevenson, M. A., McGowan, S., Anderson, N. J., Foy, R. H., Leavitt, P. R., McElarney, Y. R., Engstrom, D. R., & Pla-Rabés, S. (2016). Impacts of forestry planting on primary production in upland lakes from north-west Ireland. Global Change Biology, 22(4), 1490-1504. https://doi.org/10.1111/gcb.13194

Planted forests are increasing in many upland regions worldwide, but knowledge about their potential effects on algal communities of catchment lakes is relatively unknown. Here, the effects of afforestation were investigated using palaeolimnology at... Read More about Impacts of forestry planting on primary production in upland lakes from north-west Ireland.