All Outputs (25)

Three Centuries of Appendicectomy (2022)
Journal Article

Background Save for the contribution of Charles McBurney, who described his eponymous point and the appendicectomy incision, the history of appendicectomy is largely unknown among the medical profession. This review traces the history from the first... Read More about Three Centuries of Appendicectomy.

Nascent to novel methods to evaluate malnutrition and frailty in the surgical patient (2022)
Journal Article

Preoperative nutrition status is an important determinant of surgical outcomes, yet malnutrition assessment is not integrated into all surgical pathways. Given its importance and the high prevalence of malnutrition in patients undergoing surgical pro... Read More about Nascent to novel methods to evaluate malnutrition and frailty in the surgical patient.

Digital Informed Consent: Modernising Information Sharing in Surgery to Empower Patients (2022)
Journal Article

Background Despite the 2015 Montgomery Ruling highlighting key requisites for informed consent, little has changed to modernise data-sharing and documentation of the consent process. It can be difficult to gauge patient understanding and address all... Read More about Digital Informed Consent: Modernising Information Sharing in Surgery to Empower Patients.

Prehabilitation: high-quality evidence is still required (2022)
Journal Article

Prehabilitation comprises multidisciplinary healthcare interventions, including exercise, nutritional optimisation, and psychological preparation, which aim to dampen the metabolic response to surgery, shorten the period of recovery, reduce complicat... Read More about Prehabilitation: high-quality evidence is still required.

Identification of Surgeon Burnout via a Single-Item Measure (2022)
Journal Article

Background Burnout is endemic in surgeons in the UK and linked with poor patient safety and quality of care, mental health problems, and workforce sustainability. Mechanisms are required to facilitate the efficient identification of burnout in this... Read More about Identification of Surgeon Burnout via a Single-Item Measure.

M1 macrophages evoke an increase in polymeric immunoglobulin receptor (PIGR) expression in MDA-MB468 breast cancer cells through secretion of interleukin-1β (2022)
Journal Article

High expression of polymeric immunoglobulin receptor (PIGR) in breast cancer is associated with increased 5-year survival rate. However, the factors influencing PIGR expression in breast cancer have not been elucidated. The aim of this study was to d... Read More about M1 macrophages evoke an increase in polymeric immunoglobulin receptor (PIGR) expression in MDA-MB468 breast cancer cells through secretion of interleukin-1β.

Reply - Letter to the Editor - The usefulness of GLIM criteria to guide nutritional treatment needs further study (2022)
Journal Article

Human adaptation to immobilization: Novel insights of impacts on glucose disposal and fuel utilization (2022)
Journal Article

Background: Bed rest (BR) reduces whole-body insulin-stimulated glucose disposal (GD) and alters muscle fuel metabolism, but little is known about metabolic adaptation from acute to chronic BR nor the mechanisms involved, particularly when volunteers... Read More about Human adaptation to immobilization: Novel insights of impacts on glucose disposal and fuel utilization.

A pen in the liver (2022)
Journal Article

A 24-year-old woman with anxiety, depression, and emotionally unstable personality disorder was referred to a tertiary center 2 weeks after ingesting multiple foreign bodies. She had undergone a laparoscopic cholecystectomy and a laparotomy for extra... Read More about A pen in the liver.

Randomised clinical trials comparing antibiotic therapy with appendicectomy for uncomplicated acute appendicitis: meta-analysis (2022)
Journal Article

Background This aim of this study was to provide an updated meta-analysis comparing antibiotic therapy with appendicectomy in adults (16 years or older) with uncomplicated acute appendicitis. Methods A search for randomized clinical trials compa... Read More about Randomised clinical trials comparing antibiotic therapy with appendicectomy for uncomplicated acute appendicitis: meta-analysis.

Digital Follow-Up After Elective Laparoscopic Cholecystectomy: A Feasibility Study (2022)
Journal Article

Background: Although recommendations exist for patients to be offered a post-operative helpline or telephone follow-up appointment at discharge after cholecystectomy, implementation of these is resource-intensive. Whilst the benefits of telephone fol... Read More about Digital Follow-Up After Elective Laparoscopic Cholecystectomy: A Feasibility Study.

O038 Digital consent: modernising data-sharing in surgery and empowering patients (2022)
Journal Article

Introduction Despite the 2015 Montgomery Ruling highlighting key requisites for informed consent, little has changed to modernise data-sharing and documentation of the consent process. Although many practitioners provide supplementary information to... Read More about O038 Digital consent: modernising data-sharing in surgery and empowering patients.

The need to improve opioid prescribing and data collection in patients undergoing orthopaedic surgery (2022)
Journal Article

Utilising Electronic PROMs to Measure a Change in Health Following Elective Laparoscopic Cholecystectomy: A Feasibility Study (2022)
Journal Article

Background The collection of patient-reported outcome measures (PROMs) has many benefits for clinical practice. However, there are many barriers that prevent them from becoming a part of routine clinical care. The aim of this feasibility study was t... Read More about Utilising Electronic PROMs to Measure a Change in Health Following Elective Laparoscopic Cholecystectomy: A Feasibility Study.

Unresolved issues in perioperative nutrition: A narrative review (2022)
Journal Article

Surgical patients are at an increased risk of negative outcomes if they are malnourished or at risk of malnutrition preoperatively. Optimisation of nutritional status should be a focus throughout the perioperative continuum to promote improved surgic... Read More about Unresolved issues in perioperative nutrition: A narrative review.

Prospective validation of five malnutrition screening and assessment instruments among medical inpatients: Secondary analysis of a randomized clinical trial (2022)
Journal Article

Background & aims: Screening for malnutrition upon hospital admission is the first crucial step for proper nutritional assessment and treatment. While several nutritional screening and assessment instruments exist, there is a lack of head-to-head val... Read More about Prospective validation of five malnutrition screening and assessment instruments among medical inpatients: Secondary analysis of a randomized clinical trial.

Misappropriation of the 1986 WHO analgesic ladder: the pitfalls of labelling opioids as weak or strong (2022)
Journal Article

Opioids have a vital role in alleviating pain from cancer and surgery. Despite good intentions, it is now recognised that the original WHO Cancer Pain Relief guidance from 1986, in which opioids were classified as either weak or strong, has been both... Read More about Misappropriation of the 1986 WHO analgesic ladder: the pitfalls of labelling opioids as weak or strong.

Early Postoperative Supplementary Parenteral Nutrition (2022)
Journal Article

Molten salts have been used in solar thermal energy storage due to their high energy storage density, low cost and excellent chemical stability. However, their application is limited by “bad days” such as cloudy days and winter because the weak conce... Read More about Early Postoperative Supplementary Parenteral Nutrition.

System-level policies on appropriate opioid use, a multi-stakeholder consensus (2022)
Journal Article

Background: This consensus statement was developed because there are concerns about the appropriate use of opioids for acute pain management, with opposing views in the literature. Consensus statement on policies for system-level interventions may he... Read More about System-level policies on appropriate opioid use, a multi-stakeholder consensus.

Mapping brain activity of gut-brain signaling to appetite and satiety in healthy adults: A systematic review and functional neuroimaging meta-analysis (2022)
Journal Article

Understanding how neurohormonal gut-brain signaling regulates appetite and satiety is vital for the development of therapies for obesity and altered eating behavior. However, reported brain areas associated with appetite or satiety regulators show in... Read More about Mapping brain activity of gut-brain signaling to appetite and satiety in healthy adults: A systematic review and functional neuroimaging meta-analysis.