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All Outputs (14)

The interrater and test–retest reliability of 3 modalities of quantitative sensory testing in healthy adults and people with chronic low back pain or rheumatoid arthritis (2023)
Journal Article
Brady, S. M., Georgopoulos, V., Veldhuijzen van Zanten, J. J., Duda, J. L., Metsios, G. S., Kitas, G. D., …McWilliams, D. F. (2023). The interrater and test–retest reliability of 3 modalities of quantitative sensory testing in healthy adults and people with chronic low back pain or rheumatoid arthritis. PAIN Reports, 8(6), Article e1102. https://doi.org/10.1097/pr9.0000000000001102

Introduction: Quantitative Sensory Testing (QST) modalities used to assess central pain mechanisms require different protocols in people with different musculoskeletal conditions. Objectives: We aimed to explore the possible effects of musculo... Read More about The interrater and test–retest reliability of 3 modalities of quantitative sensory testing in healthy adults and people with chronic low back pain or rheumatoid arthritis.

Influence of central aspects of pain on self-management in people with chronic low back pain (2023)
Journal Article
Georgopoulos, V., McWilliams, D. F., Hendrick, P., & Walsh, D. A. (2023). Influence of central aspects of pain on self-management in people with chronic low back pain. Patient Education and Counseling, Article 108109. https://doi.org/10.1016/j.pec.2023.108109

Objective: This observational study investigated whether central aspects of pain are associated with selfmanagement domains in individuals with chronic low back pain (CLBP) undertaking a pain management program. Methods: Individuals with CLBP prov... Read More about Influence of central aspects of pain on self-management in people with chronic low back pain.

The Web-Based Pain-at-Work Toolkit With Telephone Support for Employees With Chronic or Persistent Pain: Protocol for a Cluster Randomized Feasibility Trial (2023)
Journal Article
Blake, H., Chaplin, W., Wainwright, E., Taylor, G., McNamee, P., McWilliams, D., …Walker-Bone, K. (2023). The Web-Based Pain-at-Work Toolkit With Telephone Support for Employees With Chronic or Persistent Pain: Protocol for a Cluster Randomized Feasibility Trial. JMIR Research Protocols, 12, Article e51474. https://doi.org/10.2196/51474

Background: Chronic or persistent pain affects people’s ability to work or be productive at work, generating high societal and economic burden. However, the provision of work-related advice and support for people with chronic pain is variable or lack... Read More about The Web-Based Pain-at-Work Toolkit With Telephone Support for Employees With Chronic or Persistent Pain: Protocol for a Cluster Randomized Feasibility Trial.

Associations of Muscle Strength with Central Aspects of Pain: Data from the Knee Pain and Related Health in the Community (KPIC) Cohort (2023)
Journal Article
McWilliams, D. F., Yue, B., Smith, S. L., Stocks, J., Doherty, M., Valdes, A. M., …Walsh, D. A. (2023). Associations of Muscle Strength with Central Aspects of Pain: Data from the Knee Pain and Related Health in the Community (KPIC) Cohort. Journal of Personalized Medicine, 13(10), Article 1450. https://doi.org/10.3390/jpm13101450

Knee pain is associated with lower muscle strength, and both contribute to disability. Peripheral and central neurological mechanisms contribute to OA pain. Understanding the relative contributions of pain mechanisms to muscle strength might help fut... Read More about Associations of Muscle Strength with Central Aspects of Pain: Data from the Knee Pain and Related Health in the Community (KPIC) Cohort.

Feasibility of conducting a cohort randomized controlled trial assessing the effectiveness of a nurse-led package of care for knee pain (2023)
Journal Article
Fuller, A., Hall, M., Nomikos, P. A., Millar, B., Ogollah, R., Valdes, A., …Abhishek, A. (in press). Feasibility of conducting a cohort randomized controlled trial assessing the effectiveness of a nurse-led package of care for knee pain. Rheumatology, Article kead432. https://doi.org/10.1093/rheumatology/kead432

Objective To evaluate the feasibility of conducting a cohort randomized controlled trial (RCT) of a nurse-led package of care for knee pain and determining a treatment sequence for use in a future trial. Methods This study was an open-label, thr... Read More about Feasibility of conducting a cohort randomized controlled trial assessing the effectiveness of a nurse-led package of care for knee pain.

Association between pain intensity and depressive symptoms in community-dwelling adults: longitudinal findings from the Survey of Health, Ageing and Retirement in Europe (SHARE) (2023)
Journal Article
Ogliari, G., Ryg, J., Andersen-Ranberg, K., Scheel-Hincke, L. L., Collins, J. T., Cowley, A., …Masud, T. (2023). Association between pain intensity and depressive symptoms in community-dwelling adults: longitudinal findings from the Survey of Health, Ageing and Retirement in Europe (SHARE). European Geriatric Medicine, 14(5), 1111-1124. https://doi.org/10.1007/s41999-023-00835-5

Purpose To investigate the longitudinal associations between pain and depressive symptoms in adults. Methods Prospective cohort study on data from 28,515 community-dwelling adults ≥ 50 years, free from depression at baseline (Wave 5), with follo... Read More about Association between pain intensity and depressive symptoms in community-dwelling adults: longitudinal findings from the Survey of Health, Ageing and Retirement in Europe (SHARE).

Health economic impact of moderate-to-severe chronic pain associated with osteoarthritis in England: a retrospective analysis of linked primary and secondary care data (2023)
Journal Article
Coates, G., Clewes, P., Lohan, C., Stevenson, H., Wood, R., Tritton, T., …Walsh, D. (2023). Health economic impact of moderate-to-severe chronic pain associated with osteoarthritis in England: a retrospective analysis of linked primary and secondary care data. BMJ Open, 13(7), Article e067545. https://doi.org/10.1136/bmjopen-2022-067545

Objective: Despite the prevalence of osteoarthritis (OA) in England, few studies have examined the health economic impact of chronic pain associated with OA. The aim of this study was to compare outcomes in patients with moderate-to-severe chronic pa... Read More about Health economic impact of moderate-to-severe chronic pain associated with osteoarthritis in England: a retrospective analysis of linked primary and secondary care data.

The bidirectional relationship between chronic joint pain and frailty: data from the Investigating Musculoskeletal Health and Wellbeing cohort (2023)
Journal Article
Chaplin, W. J., McWilliams, D. F., Millar, B. S., Gladman, J. R. F., & Walsh, D. A. (2023). The bidirectional relationship between chronic joint pain and frailty: data from the Investigating Musculoskeletal Health and Wellbeing cohort. BMC Geriatrics, 23(1), Article 273. https://doi.org/10.1186/s12877-023-03949-4

Background: Pain and frailty are associated, but this relationship is insufficiently understood. We aimed to test whether there is a unidirectional or bidirectional relationship between joint pain and frailty. Methods: Data were from Investigating Mu... Read More about The bidirectional relationship between chronic joint pain and frailty: data from the Investigating Musculoskeletal Health and Wellbeing cohort.

P073 Comparative effectiveness of different exercise interventions on central sensitisation indices in humans: A systematic review and network meta-analysis (2023)
Journal Article
Abd Elkhabir, A. A., McWilliams, D. F., Smith, S., Chaplin, W., Salimian, M., Georgopoulos, V., …Walsh, D. A. (2023). P073 Comparative effectiveness of different exercise interventions on central sensitisation indices in humans: A systematic review and network meta-analysis. Rheumatology, 62(Supplement 2), Article kead104.114. https://doi.org/10.1093/rheumatology/kead104.114

Background/Aims Exercise has shown a promising effect in reducing central sensitisation (CS), but it is unknown which exercise type is the most effective. This review aimed to rank and compare the effectiveness of different exercise interventions o... Read More about P073 Comparative effectiveness of different exercise interventions on central sensitisation indices in humans: A systematic review and network meta-analysis.

Inflammatory and Noninflammatory Disease Activity in Rheumatoid Arthritis: The Effect of Pain on Personalized Medicine (2023)
Journal Article
McWilliams, D. F., & Walsh, D. A. (2023). Inflammatory and Noninflammatory Disease Activity in Rheumatoid Arthritis: The Effect of Pain on Personalized Medicine. Journal of Rheumatology, 50(6), 721-723. https://doi.org/10.3899/jrheum.230158

Disease activity in rheumatoid arthritis (RA) is often described in terms of inflammation, although noninflammatory mechanisms are also integral to the disease. Pain is the most important symptom for many people with RA, and is therefore a key compo... Read More about Inflammatory and Noninflammatory Disease Activity in Rheumatoid Arthritis: The Effect of Pain on Personalized Medicine.

Serum Metabolome Analysis Identified Amino-Acid Metabolism Associated With Pain in People With Symptomatic Knee Osteoarthritis – A Cross-Sectional Study (2023)
Journal Article
Mehta, O., Vijay, A., Gohir, S. A., Kelly, T., Zhang, W., Doherty, M., …Valdes, A. M. (2023). Serum Metabolome Analysis Identified Amino-Acid Metabolism Associated With Pain in People With Symptomatic Knee Osteoarthritis – A Cross-Sectional Study. Journal of Pain, https://doi.org/10.1016/j.jpain.2023.02.023

Osteoarthritis (OA) is the most common arthritis affecting synovial joints such as knees and hips of millions of people globally. Usage-related joint pain and reduced function are the most common symptoms experienced by people with OA. To improve pai... Read More about Serum Metabolome Analysis Identified Amino-Acid Metabolism Associated With Pain in People With Symptomatic Knee Osteoarthritis – A Cross-Sectional Study.

How people with knee pain understand why their pain changes or remains the same over time: A qualitative study (2023)
Journal Article
Walsh, D. A., Rathbone, J., Akin-Akinyosoye, K., Fernandes, G. S., Valdes, A. M., McWilliams, D. F., …Ferguson, E. (2023). How people with knee pain understand why their pain changes or remains the same over time: A qualitative study. Osteoarthritis and Cartilage Open, 5(2), Article 100345. https://doi.org/10.1016/j.ocarto.2023.100345

Objectives Guidelines recommend knee osteoarthritis pain management based on biopsychosocial mechanisms. Treatment adherence and effectiveness may be affected if there is a mismatch between patient perspectives and treatment focus. We therefore exam... Read More about How people with knee pain understand why their pain changes or remains the same over time: A qualitative study.

Chronic pain in people living with dementia: challenges to recognising and managing pain, and personalising intervention by phenotype (2023)
Journal Article
Collins, J. T., Harwood, R. H., Cowley, A., Di Lorito, C., Ferguson, E., Minicucci, M. F., …Gladman, J. R. (2023). Chronic pain in people living with dementia: challenges to recognising and managing pain, and personalising intervention by phenotype. Age and Ageing, 52(1), Article afac306. https://doi.org/10.1093/ageing/afac306

Pain is common in people with dementia, and pain can exacerbate the behavioural and psychological symptoms of dementia. Effective pain management is challenging, not least in people with dementia. Impairments of cognition, communication and abstract... Read More about Chronic pain in people living with dementia: challenges to recognising and managing pain, and personalising intervention by phenotype.