Skip to main content

Research Repository

Advanced Search

All Outputs (6)

In vivo evaluation of different formulation strategies for sustained release injectables of a poorly soluble HIV protease inhibitor (2014)
Journal Article

At present no scientific rationale exists for selecting a particular enabling strategy to formulate a poorly water-soluble drug, although this is crucial as it will influence the in vivo performance of the resulting formulation. This study provides a... Read More about In vivo evaluation of different formulation strategies for sustained release injectables of a poorly soluble HIV protease inhibitor.

Combination of (M)DSC and Surface Analysis to Study the Phase Behaviour and Drug Distribution of Ternary Solid Dispersions (2014)
Journal Article

Purpose: Miscibility of the different compounds that make up a solid dispersion based formulation play a crucial role in the drug release profile and physical stability of the solid dispersion as it defines the phase behaviour of the dispersion. The... Read More about Combination of (M)DSC and Surface Analysis to Study the Phase Behaviour and Drug Distribution of Ternary Solid Dispersions.

Spectroscopic Studies of Internal Injector Deposits (IDID) Resulting from the Use of Non-Commercial Low Molecular Weight Polyisobutylenesuccinimide (PIBSI) (2014)
Journal Article

Copyright © 2014 SAE International. Since 2009, there has been a rise in deposits of various types found in diesel fuel injection systems. They have been identified in the filter, the injector tip and recently inside the injector. The latter internal... Read More about Spectroscopic Studies of Internal Injector Deposits (IDID) Resulting from the Use of Non-Commercial Low Molecular Weight Polyisobutylenesuccinimide (PIBSI).