Controlling the release of indomethacin from glass solutions layered with a rate controlling membrane using fluid-bed processing. Part 1: Surface and cross-sectional chemical analysis

Dereymaker, Aswin; Scurr, David J.; Steer, Elisabeth D.; Roberts, Clive J.; Van den Mooter, Guy

doi:10.1021/acs.molpharmaceut.6b01023

All Outputs (5)

An augmented delivery of the anticancer agent, curcumin, to the colon (2017)
Journal Article

This work describes the formulation aspects of an orally viable curcumin-containing mucoadhesive nanoparticulate system for management of colon cancer. Curcumin is documented to possess anticancer properties whilst modified citrus pectin yields a gal... Read More about An augmented delivery of the anticancer agent, curcumin, to the colon.

3D printing of tablets using inkjet with UV photoinitiation (2017)
Journal Article

Additive manufacturing (AM) offers significant potential benefits in the field of drug delivery and pharmaceutical/medical device manufacture. Of AM processes, 3D inkjet printing enables precise deposition of a formulation, whilst offering the potent... Read More about 3D printing of tablets using inkjet with UV photoinitiation.

3D inkjet printing of tablets exploiting bespoke complex geometries for controlled and tuneable drug release (2017)
Journal Article

A hot melt 3D inkjet printing method with the potential to manufacture formulations in complex and adaptable geometries for the controlled loading and release of medicines is presented. This first use of a precisely controlled solvent free inkjet pri... Read More about 3D inkjet printing of tablets exploiting bespoke complex geometries for controlled and tuneable drug release.

Multiboronic acid-conjugated chitosan scaffolds with glucose selectivity to insulin release (2017)
Journal Article

The principal challenge for the use of boronic acids (BA) as glucose sensors is their lack of specificity for glucose. We examined the selectivity of and insulin release from two boronic acids- (2-formyl-3-thienylboronic acid (FTBA) and 4-formylpheny... Read More about Multiboronic acid-conjugated chitosan scaffolds with glucose selectivity to insulin release.

Controlling the release of indomethacin from glass solutions layered with a rate controlling membrane using fluid-bed processing. Part 1: Surface and cross-sectional chemical analysis (2017)
Journal Article

Fluid bed coating has been shown to be a suitable manufacturing technique to formulate poorly soluble drugs in glass solutions. Layering inert carriers with a drug–polymer mixture enables these beads to be immediately filled into capsules, thus avoid... Read More about Controlling the release of indomethacin from glass solutions layered with a rate controlling membrane using fluid-bed processing. Part 1: Surface and cross-sectional chemical analysis.