All Outputs (9)

Application of biorelevant saliva-based dissolution for optimisation of orally disintegrating formulations of felodipine (2018)
Journal Article

The oral cavity is of great importance to the performance of orally retained formulations, including: orally disintegrating tablets, taste-masked formulations, and buccal/sublingual delivery systems. With regards to in vitro dissolution assessment of... Read More about Application of biorelevant saliva-based dissolution for optimisation of orally disintegrating formulations of felodipine.

Mucoadhesive chitosan-coated nanostructured lipid carriers for oral delivery of amphotericin B (2018)
Journal Article

This study describes the properties of an amphotericin B-containing mucoadhesive nanostructured lipid carrier (NLC), with the intent to maximize uptake within the gastrointestinal tract. We have reported previously that lipid nanoparticles can signif... Read More about Mucoadhesive chitosan-coated nanostructured lipid carriers for oral delivery of amphotericin B.

Extrusion 3D printing of paracetamol tablets from a single formulation with tunable release profiles through control of tablet geometry (2018)
Journal Article

An extrusion based 3D printer was used to fabricate paracetamol tablets with different geometries (mesh, ring, and solid) from a single paste-based formulation formed from standard pharmaceutical ingredients. The tablets demonstrate that tunable drug... Read More about Extrusion 3D printing of paracetamol tablets from a single formulation with tunable release profiles through control of tablet geometry.

Using total specific cost indices to compare the cost performance of additive manufacturing for the medical devices domain (2018)
Journal Article

The label additive manufacturing, also known as three-dimensional printing, serves as an umbrella term for a number of technologies designed to deposit product geometries directly from build materials and digital design information. However, as a rel... Read More about Using total specific cost indices to compare the cost performance of additive manufacturing for the medical devices domain.

The role of dipole interactions in hyperthermia heating colloidal clusters of densely-packed superparamagnetic nanoparticles (2018)
Journal Article

This work aims to investigate the influence of inter-particle dipole interactions on hyperthermia heating colloidal clusters of densely-packed Fe3O4 nanoparticles at low field intensity. Emulsion droplet solvent evaporation method was used to assembl... Read More about The role of dipole interactions in hyperthermia heating colloidal clusters of densely-packed superparamagnetic nanoparticles.

Multiple linear regression modelling to predict the stability of polymer-drug solid dispersions: comparison of the effects of polymers and manufacturing methods on solid dispersion stability (2018)
Journal Article

Solid dispersions can be a successful way to enhance the bioavailability of poorly soluble drugs. Here 60 solid dispersion formulations were produced using ten chemically diverse, neutral, poorly soluble drugs, three commonly used polymers, and two m... Read More about Multiple linear regression modelling to predict the stability of polymer-drug solid dispersions: comparison of the effects of polymers and manufacturing methods on solid dispersion stability.

The application of X-ray micro Computed Tomography imaging for tracing particle movement in soil (2018)
Journal Article

Despite significant advances in recent years in the application of sensing and imaging technologies to the study of the hydraulic behaviour of soils, our understanding of how solutes and particulate matter move through soil is still limited and often... Read More about The application of X-ray micro Computed Tomography imaging for tracing particle movement in soil.

3D extrusion printing of high drug loading immediate release paracetamol tablets (2018)
Journal Article

The manufacture of immediate release high drug loading paracetamol oral tablets was achieved using an extrusion based 3D printer from a premixed water based paste formulation. The 3D printed tablets demonstrate that a very high drug (paracetamol) loa... Read More about 3D extrusion printing of high drug loading immediate release paracetamol tablets.

Identification of novel ‘inks’ for 3D printing using high throughput screening: bioresorbable photocurable polymers for controlled drug delivery (2018)
Journal Article

A robust discovery methodology is presented to identify novel biomaterials suitable for 3D printing. Currently the application of Additive Manufacturing is limited by the availability of functional inks, especially in the area of biomaterials-this me... Read More about Identification of novel ‘inks’ for 3D printing using high throughput screening: bioresorbable photocurable polymers for controlled drug delivery.