All Outputs (96)

Porphyromonas pasteri and Prevotella nanceiensis in the sputum microbiota are associated with increased decline in lung function in individuals with cystic fibrosis (2022)
Journal Article

Although anaerobic bacteria exist in abundance in cystic fibrosis (CF) airways, their role in disease progression is poorly understood. We hypothesized that the presence and relative abundance of the most prevalent, live, anaerobic bacteria in sputum... Read More about Porphyromonas pasteri and Prevotella nanceiensis in the sputum microbiota are associated with increased decline in lung function in individuals with cystic fibrosis.

Pulse oximeter measurements vary across ethnic groups: an observational study in patients with COVID-19 (2022)
Journal Article

Ethnicity and suicide risk: A population-based study from England (2021)
Journal Article

Using multiple linked electronic health databases, we conducted a large case-control study in England from 2001 through 2019 to examine the association between ethnicity and suicide risk. Asian, Black and Other ethnic groups had a significantly lower... Read More about Ethnicity and suicide risk: A population-based study from England.

2-Alkyl-4-quinolone quorum sensing molecules are biomarkers for culture-independent Pseudomonas aeruginosa burden in adults with cystic fibrosis (2021)
Journal Article

Introduction. Pseudomonas aeruginosa produces quorum sensing signalling molecules including 2-alkyl-4-quinolones (AQs), which regulate virulence factor production in the cystic fibrosis (CF) airways. Hypothesis/Gap statement. Culture can lead to cond... Read More about 2-Alkyl-4-quinolone quorum sensing molecules are biomarkers for culture-independent Pseudomonas aeruginosa burden in adults with cystic fibrosis.

Chest Radiograph Scoring Alone or Combined with Other Risk Scores for Predicting Outcomes in COVID-19 (2021)
Journal Article

Background Radiographic severity may help predict patient deterioration and outcomes from COVID-19 pneumonia. Purpose To assess the reliability and reproducibility of three chest radiograph reporting systems (radiographic assessment of lung edema [RA... Read More about Chest Radiograph Scoring Alone or Combined with Other Risk Scores for Predicting Outcomes in COVID-19.

Novel detection of specific bacterial quorum sensing molecules in saliva: Potential non-invasive biomarkers for pulmonary Pseudomonas aeruginosa in cystic fibrosis (2021)
Journal Article

Pseudomonas aeruginosa produces specific signalling molecules, 2-alkyl-4-quinolones (AQs) that are detectable in the sputum of adults with cystic fibrosis (CF) and who have pulmonary infection with this opportunistic pathogen. This study aimed to det... Read More about Novel detection of specific bacterial quorum sensing molecules in saliva: Potential non-invasive biomarkers for pulmonary Pseudomonas aeruginosa in cystic fibrosis.

Prospective cohort study of exposure to tobacco imagery in popular films and smoking uptake among children in southern India (2021)
Journal Article

Background Exposure to tobacco imagery in films causes young people to start smoking. Popular Indian films contain high levels of tobacco imagery, but those that do are required by law to display onscreen health warnings when smoking imagery occurs a... Read More about Prospective cohort study of exposure to tobacco imagery in popular films and smoking uptake among children in southern India.

An Emerging Problem of Shisha Smoking among High School Students in Ethiopia (2021)
Journal Article

Shisha smoking is also known as hookah, water pipe, goza, and nargile. Shisha use among the young is increasing globally. Shisha smoke results in a high concentration of carbon monoxide, tar, nicotine, and heavy metals which can be toxic to humans, e... Read More about An Emerging Problem of Shisha Smoking among High School Students in Ethiopia.

Mortality rates immediately after severe hurricanes in Cuba have decreased over the past three decades (2021)
Journal Article

Objectives The objective of this study is to understand how Cuba responds to extreme weather events, which can help identify and disseminate good public health practice. Study design The study design of this study is an observational study u... Read More about Mortality rates immediately after severe hurricanes in Cuba have decreased over the past three decades.

Development and evaluation of a brief educational cartoon on trainee clinicians’ awareness of risks of ionising-radiation exposure: a feasibility pre-post intervention study of a novel educational tool to promote patient safety (2020)
Journal Article

Background Over recent decades, CT scans have become routinely available and are used in both acute medical and outpatient environments. However, there is a small increase in the risk of adverse consequences, including an increase in the risk of both... Read More about Development and evaluation of a brief educational cartoon on trainee clinicians’ awareness of risks of ionising-radiation exposure: a feasibility pre-post intervention study of a novel educational tool to promote patient safety.

Two measures of systemic inflammation are positively associated with haemoglobin levels in adolescent girls living in rural India: a cross-sectional study (2020)
Journal Article

Objective: This study tested the hypothesis that systemic inflammation is inversely associated with haemoglobin levels in adolescent girls in India. Methods: The study population consisted of adolescent girls aged between 10 and 19years living in a r... Read More about Two measures of systemic inflammation are positively associated with haemoglobin levels in adolescent girls living in rural India: a cross-sectional study.

Exposure to tobacco imagery in popular films and the risk of ever smoking among children in southern India (2020)
Journal Article

Background Exposure to smoking in films is a recognised cause of smoking uptake among children. In India, in an attempt to protect children, films containing smoking are required to include tobacco control messaging including audiovisual disclaimers,... Read More about Exposure to tobacco imagery in popular films and the risk of ever smoking among children in southern India.

Patients' attitudes towards cost feedback to doctors to prevent unnecessary testing: a qualitative focus group study (2020)
Journal Article

© 2020 The Authors Objectives: There is a need to improve efficiency in healthcare delivery without compromising quality of care. One approach is the development and evaluation of behavioural strategies to reduce unnecessary use of common tests. Howe... Read More about Patients' attitudes towards cost feedback to doctors to prevent unnecessary testing: a qualitative focus group study.

Phenotypic and functional translation of IL33 genetics in asthma (2020)
Journal Article

© 2020 Background: Asthma is a complex disease with multiple phenotypes that may differ in disease pathobiology and treatment response. IL33 single nucleotide polymorphisms (SNPs) have been reproducibly associated with asthma. IL33 levels are elevate... Read More about Phenotypic and functional translation of IL33 genetics in asthma.

Hospital doctors’ attitudes to brief educational messages that aim to modify diagnostic test requests: a qualitative study (2020)
Journal Article

BACKGROUND: Avoidable use of diagnostic tests can both harm patients and increase the cost of healthcare. Nudge-type educational interventions have potential to modify clinician behaviour while respecting clinical autonomy and responsibility, but the... Read More about Hospital doctors’ attitudes to brief educational messages that aim to modify diagnostic test requests: a qualitative study.

Phenotypic and functional translation of IL1RL1 locus polymorphisms in lung tissue and asthmatic airway epithelium (2020)
Journal Article

The IL1RL1 (ST2) gene locus is robustly associated with asthma; however, the contribution of single nucleotide polymorphisms (SNPs) in this locus to specific asthma subtypes and the functional mechanisms underlying these associations remain to be def... Read More about Phenotypic and functional translation of IL1RL1 locus polymorphisms in lung tissue and asthmatic airway epithelium.

Prevalence and risk factors for wheeze, decreased forced expiratory volume in 1 s and bronchoconstriction in young children living in Havana, Cuba: a population-based cohort study (2020)
Journal Article

Objectives: Asthma has not been extensively studied in low-income and middle-income countries, where risk factors and access to treatment may differ from more affluent countries. We aimed to identify the prevalence of asthma and local risk factors in... Read More about Prevalence and risk factors for wheeze, decreased forced expiratory volume in 1 s and bronchoconstriction in young children living in Havana, Cuba: a population-based cohort study.

The potential to quantify polypharmacy in older adult hospital inpatients using electronic prescribing software: A feasibility study (2020)
Journal Article

Polypharmacy in older adults is a growing problem, as some drugs may be either unnecessary or even harmful. Admission to hospital under a Medicine for the Elderly specialist physicians represents an opportunity to review patients’ medication. The rec... Read More about The potential to quantify polypharmacy in older adult hospital inpatients using electronic prescribing software: A feasibility study.

Weight, height and midupper arm circumference are associated with haemoglobin levels in adolescent girls living in rural India: A cross-sectional study (2019)
Journal Article

Objective: We aimed to explore the association of physical parameters with haemoglobin (Hb) levels to test the hypothesis that impaired physical development is associated with anaemia. Methods: A cross-sectional survey study recruited adolescent... Read More about Weight, height and midupper arm circumference are associated with haemoglobin levels in adolescent girls living in rural India: A cross-sectional study.

Evaluation of the impact of a brief educational message on clinicians’ awareness of risks of ionising-radiation exposure in imaging investigations: a pilot pre-post intervention study (2019)
Journal Article

Background: In the context of increasing availability of computed tomography (CT) scans, judicious use of ionising radiation is a priority to minimise the risk of future health problems. Hence, education of clinicians on the risks and benefits of CT... Read More about Evaluation of the impact of a brief educational message on clinicians’ awareness of risks of ionising-radiation exposure in imaging investigations: a pilot pre-post intervention study.