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All Outputs (10)

Approaches to risk ratio estimation in a regression discontinuity design: Application to the prescription of statins for cholesterol reduction in UK primary care (2023)
Journal Article

In recent years regression discontinuity designs have been used increasingly for the estimation of treatment effects in observational medical data where a rule-based decision to apply treatment is taken using a continuous assignment variable. Most re... Read More about Approaches to risk ratio estimation in a regression discontinuity design: Application to the prescription of statins for cholesterol reduction in UK primary care.

Protocol for the feasibility and implementation study of a model of best practice in primary care led postdiagnostic dementia care: PriDem. (2023)
Journal Article

Introduction: Care is often inadequate and poorly integrated after a dementia diagnosis. Research and policy highlight the unaffordability and unsustainability of specialist-led support, and instead suggest a task-shared model, led by primary care. T... Read More about Protocol for the feasibility and implementation study of a model of best practice in primary care led postdiagnostic dementia care: PriDem..

The impact of temporal lobe epilepsy surgery on picture naming and its relationship to network metric change. (2023)
Journal Article

Background: Anterior temporal lobe resection (ATLR) is a successful treatment for medically-refractory temporal lobe epilepsy (TLE). In the language-dominant hemisphere, 30%- 50% of individuals experience a naming decline which can impact upon daily... Read More about The impact of temporal lobe epilepsy surgery on picture naming and its relationship to network metric change..

Contribution of White Matter Fiber Bundle Damage to Language Change After Surgery for Temporal Lobe Epilepsy (2023)
Journal Article

Background and ObjectivesIn medically refractory temporal lobe epilepsy (TLE), 30%-50% of patients experience substantial language decline after resection in the language-dominant hemisphere. In this study, we investigated the contribution of white m... Read More about Contribution of White Matter Fiber Bundle Damage to Language Change After Surgery for Temporal Lobe Epilepsy.

Zibotentan in systemic sclerosis-associated chronic kidney disease: a phase II randomised placebo-controlled trial (2022)
Journal Article

Background We report results from a phase II randomised placebo-controlled trial assessing zibotentan, a highly selective endothelin receptor antagonist (ERA), in chronic kidney disease (CKD) secondary to systemic sclerosis (SSc). Methods This t... Read More about Zibotentan in systemic sclerosis-associated chronic kidney disease: a phase II randomised placebo-controlled trial.

Regression discontinuity designs for time-to-event outcomes: An approach using accelerated failure time models (2022)
Journal Article

Regression discontinuity designs (RDDs) have been developed for the estimation of treatment effects using observational data, where a treatment is administered using an externally defined decision rule, linked to a continuous assignment variable. Typ... Read More about Regression discontinuity designs for time-to-event outcomes: An approach using accelerated failure time models.

Seizure outcomes in people with drug-resistant focal epilepsy evaluated for surgery but do not proceed (2021)
Journal Article

Objective: To ascertain seizure outcomes in people with drug-resistant focal epilepsy considered for epilepsy surgery but who did not proceed. Methods: We identified people discussed at a weekly presurgical epilepsy multi-disciplinary (MDT) meeting f... Read More about Seizure outcomes in people with drug-resistant focal epilepsy evaluated for surgery but do not proceed.