All Outputs (169)

Development and Validation of Quality of Life Measurement Tools Used in Older Peoples’ Care Homes: a scoping review protocol (2021)
Working Paper

Introduction There is a high prevalence of frailty and cognitive impairment within care home population. These wide-ranging experiences and needs impact on residents’ quality of life. Therefore, measuring Quality of Life (QOL) in residents as part... Read More about Development and Validation of Quality of Life Measurement Tools Used in Older Peoples’ Care Homes: a scoping review protocol.

Feasibility RCT of neuromuscular electrical stimulation; an Intervention to Maintain and improve neuroMuscular function during periods of Immobility (IMMI): Protocol (2021)
Working Paper

East Midlands Research into Ageing Network (EMRAN) is a research collaboration across the East Midlands to facilitate collaborative applied clinical research into ageing and the care of older people. EMRAN was set up by NIHR CLAHRC East Midlands and... Read More about Feasibility RCT of neuromuscular electrical stimulation; an Intervention to Maintain and improve neuroMuscular function during periods of Immobility (IMMI): Protocol.

GPs’ involvement to improve care quality in care homes in the UK: a realist review (2021)
Journal Article

Background Organising health-care services for residents living in care homes is an important area of development in the UK and elsewhere. Medical care is provided by general practitioners in the UK, and the unique arrangement of the NHS means that... Read More about GPs’ involvement to improve care quality in care homes in the UK: a realist review.

Nitric oxide for the prevention and treatment of viral, bacterial, protozoal and fungal infections (2021)
Journal Article

Although the antimicrobial potential of nitric oxide (NO) is widely published, it is little used clinically. NO is a key signalling molecule modulating vascular, neuronal, inflammatory and immune responses. Endogenous antimicrobial activity is largel... Read More about Nitric oxide for the prevention and treatment of viral, bacterial, protozoal and fungal infections.

Rehabilitation potential in older people living with frailty: a systematic mapping review (2021)
Journal Article

Background: Following periods of acute ill-health and injury, older people are frequently assessed and provided with rehabilitation services. Healthcare practitioners are required to make nuanced decisions about which patients are likely to benefit f... Read More about Rehabilitation potential in older people living with frailty: a systematic mapping review.

Effects of neuromuscular electrical stimulation (NMES) in acutely hospitalised adult patients -protocol for a systematic review of randomised controlled trials (RCTs) (2021)
Working Paper

Nitric oxide for the prevention and treatment of viral, bacterial, protozoal and fungal infections [version 1; peer review: 1 approved with reservations] (2021)
Journal Article

Although the antimicrobial potential of nitric oxide (NO) is widely published, it is little used clinically. NO is a key signalling molecule modulating vascular, neuronal, inflammatory and immune responses. Endogenous antimicrobial activity is largel... Read More about Nitric oxide for the prevention and treatment of viral, bacterial, protozoal and fungal infections [version 1; peer review: 1 approved with reservations].

Communication during the COVID-19 Pandemic: Evaluation-Study on Self-Perceived Competences and Views of Health Care Professionals (2021)
Journal Article

Purpose The aims of this study were to describe communication experiences while wearing a mask during COVID-19 pandemic in 2020, in order to identify possible mask-related barriers to COVID-19-adapted communications and to investigate whether the AB... Read More about Communication during the COVID-19 Pandemic: Evaluation-Study on Self-Perceived Competences and Views of Health Care Professionals.

Research into ageing and frailty (2021)
Journal Article

Research into ageing covers opportunities and challenges posed by an older population, and research to understand the ageing processes across the lifespan. The evidence base for Comprehensive Geriatric Assessment (CGA) is well established and efforts... Read More about Research into ageing and frailty.

FebriDx point-of-care test in patients with suspected COVID-19: a pooled diagnostic accuracy study (2021)
Working Paper

Background: Point-of-care (POC) tests for COVID-19 could relieve pressure on isolation resource, support infection prevention and control, and help commence more timely and appropriate treatment. We aimed to undertake a systematic review and pooled d... Read More about FebriDx point-of-care test in patients with suspected COVID-19: a pooled diagnostic accuracy study.

HEARTS, minds and souls—it is time for geriatricians to bring more to continence management (2021)
Journal Article

Urinary incontinence (UI), the involuntary loss of urine, is a common health condition that may decrease the quality of life and which increases in incidence and prevalence with age. Recent epidemiologic data suggest an overall prevalence of 38% in w... Read More about HEARTS, minds and souls—it is time for geriatricians to bring more to continence management.

Optimal care for the management of older people non-weight bearing after lower limb fracture: a consensus study (2021)
Journal Article

Background: Older people who are non-weight-bearing after a lower limb fracture are at risk of poor outcomes but there are no clinical guidelines for this group of patients. Given the paucity of the research evidence base, we conducted a consensus ex... Read More about Optimal care for the management of older people non-weight bearing after lower limb fracture: a consensus study.

Optimal management of older people with frailty non-weight bearing after lower limb fracture: a scoping review (2021)
Journal Article

Background Patients with lower limb fractures who are non-weight bearing are at risk of the complications of the associated immobility and disability, particularly people with frailty, but there is lack of clarity about what constitutes optimal ca... Read More about Optimal management of older people with frailty non-weight bearing after lower limb fracture: a scoping review.

COVID-19 point-of-care testing in care homes: what are the lessons for policy and practice? (2021)
Journal Article

COVID-19 has devastated care homes. Point of care tests (POCTs), mainly using Lateral Flow Devices (LFDs), have been deployed hurriedly without much consideration of their usability or impact on care workflow. Even after the pandemic POCTs, particula... Read More about COVID-19 point-of-care testing in care homes: what are the lessons for policy and practice?.

Point of Care Testing using rapid automated Antigen Testing for SARS- COV-2 in Care Homes -an exploratory safety, usability and diagnostic agreement evaluation (2021)
Working Paper

Is point-of-care testing feasible and safe in care homes in England? An exploratory usability and accuracy evaluation of a point-of-care polymerase chain reaction test for SARS-CoV-2 (2021)
Journal Article

Introduction: Reliable rapid testing for COVID-19 is needed in care homes to reduce the risk of outbreaks and enable timely care. This study aimed to examine the usability and test performance of a point of care polymerase chain reaction (PCR) test... Read More about Is point-of-care testing feasible and safe in care homes in England? An exploratory usability and accuracy evaluation of a point-of-care polymerase chain reaction test for SARS-CoV-2.

Exploring rehabilitation potential in older people living with frailty: a qualitative focus group study (2021)
Journal Article

Background: Rehabilitation interventions are frequently cited as key in supporting frail older people’s recovery following periods of decompensation and acute ill-health. Clinicians are required to make decisions about a patient’s potential to respon... Read More about Exploring rehabilitation potential in older people living with frailty: a qualitative focus group study.

How Quality Improvement Collaboratives Work to Improve Healthcare in Care Homes: A Realist Evaluation (2021)
Journal Article

Background Quality improvement collaboratives (QICs) bring together multidisciplinary teams in a structured process to improve care quality. How QICs can be used to support healthcare improvement in care homes is not fully understood. Methods A... Read More about How Quality Improvement Collaboratives Work to Improve Healthcare in Care Homes: A Realist Evaluation.

Care homes, their communities, and resilience in the face of the COVID-19 pandemic: interim findings from a qualitative study (2021)
Journal Article

Background: From late February 2020, English care homes rapidly adapted their practices in response to the COVID-19 pandemic. In addition to accommodating new guidelines and policies, staff had to adjust to rapid reconfiguration of services external... Read More about Care homes, their communities, and resilience in the face of the COVID-19 pandemic: interim findings from a qualitative study.

Risk of incident dementia and cognitive impairment in patients with chronic obstructive pulmonary disease (COPD): A large UK population-based study (2020)
Journal Article

Background: Although cognitive impairment and dementia are common comorbidities in patients with chronic obstructive pulmonary disease (COPD), estimates of incidence following a diagnosis of COPD are inconclusive. Objective: To determine the incidenc... Read More about Risk of incident dementia and cognitive impairment in patients with chronic obstructive pulmonary disease (COPD): A large UK population-based study.