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Application and potential of artificial intelligence in neonatal medicine

Chang Kwok, T’ng; Henry, Caroline; Saffaran, Sina; Meeus, Marisse; Bates, Declan; Van Laere, David; Boylan, Geraldine; Boardman, James P.; Sharkey, Don

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Clinical Research Fellow in Neonatal Medicine

Caroline Henry

Sina Saffaran

Marisse Meeus

Declan Bates

David Van Laere

Geraldine Boylan

James P. Boardman

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Professor of Neonatal Medicine and Technologies


Neonatal care is becoming increasingly complex with large amounts of rich, routinely recorded physiological, diagnostic and outcome data. Artificial intelligence (AI) has the potential to harness this vast quantity and range of information and become a powerful tool to support clinical decision making, personalised care, precise prognostics, and enhance patient safety. Current AI approaches in neonatal medicine include tools for disease prediction and risk stratification, neurological diagnostic support and novel image recognition technologies. Key to the integration of AI in neonatal medicine is the understanding of its limitations and a standardised critical appraisal of AI tools. Barriers and challenges to this include the quality of datasets used, performance assessment, and appropriate external validation and clinical impact studies. Improving digital literacy amongst healthcare professionals and cross-disciplinary collaborations are needed to harness the full potential of AI to help take the next significant steps in improving neonatal outcomes for high-risk infants.


Chang Kwok, T., Henry, C., Saffaran, S., Meeus, M., Bates, D., Van Laere, D., …Sharkey, D. (2022). Application and potential of artificial intelligence in neonatal medicine. Seminars in Fetal and Neonatal Medicine, 27(5), Article 101346.

Journal Article Type Article
Acceptance Date Mar 31, 2022
Online Publication Date Apr 18, 2022
Publication Date Oct 1, 2022
Deposit Date Apr 26, 2022
Publicly Available Date Apr 28, 2022
Journal Seminars in Fetal and Neonatal Medicine
Print ISSN 1744-165X
Electronic ISSN 1878-0946
Publisher Elsevier
Peer Reviewed Peer Reviewed
Volume 27
Issue 5
Article Number 101346
Keywords Pediatrics, Perinatology and Child Health
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