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The importance of antioxidant micronutrients and vitamins in pregnancy

Mistry, Hiten D.; Williams, Paula J.

The importance of antioxidant micronutrients and vitamins in pregnancy Thumbnail


Hiten D. Mistry

Paula J. Williams


Pregnancy places increased demands on the mother to provide not only adequate nutrition to support her own health but also to enable the growth and development of the conceptus. A key role of a number of micronutrients and vitamins is their function as essential cofactors for or themselves acting as antioxidants. Oxidative stress is generated during normal placental development however expression of antioxidant enzymes within the placenta provides protection from undue damage. However, when supply of these antioxidant associated micronutrients is limited, antioxidant protection can be reduced, culminating in oxidative stress within both the placenta and the maternal circulation resulting in adverse pregnancy outcomes. The present literature review was prepared to summarise current understanding of the importance of micronutrient antioxidants in pregnancy. Comprehensive literature searching was performed using PubMed and Google Scholar. Sensitive search strategies were combined with relevant medical subject headings and text words.’ This review summarises the role of antioxidant micronutrients in healthy and pathological pregnancy, emphasising the need for further research in this area.


Mistry, H. D., & Williams, P. J. (2011). The importance of antioxidant micronutrients and vitamins in pregnancy. Oxidative Medicine and Cellular Longevity, 2011,

Journal Article Type Article
Acceptance Date Jun 6, 2011
Publication Date Aug 1, 2011
Deposit Date Jul 19, 2017
Publicly Available Date Jul 19, 2017
Journal Oxidative Medicine and Cellular Longevity
Print ISSN 1942-0900
Electronic ISSN 1942-0994
Publisher Hindawi
Peer Reviewed Peer Reviewed
Volume 2011
Public URL
Publisher URL
Contract Date Jul 19, 2017


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