Sheema Almozyan
Wnt/GSK-3β mediates posttranslational modifications of FLYWCH1 to regulate intestinal epithelial function and tumorigenesis in the colon
Almozyan, Sheema; Babaei-Jadidi, Roya; Aljohani, Abrar; Youssefi, Sepideh; Dalleywater, William; Kadam, Prerna; Spencer-Dene, Bradley; Rakha, Emad; Ilyas, Mohammad; Shams Nateri, Abdolrahman
Authors
Dr ROYA BABAEI-JADIDI Roya.Babaei-jadidi@nottingham.ac.uk
RESEARCH FELLOW
Abrar Aljohani
Dr SEPIDEH YOUSSEFI Sepideh.Youssefi@nottingham.ac.uk
Research Associate
Dr WILLIAM DALLEYWATER William.Dalleywater@nottingham.ac.uk
CLINICAL ASSISTANT PROFESSOR (NIHR CLINICAL LECTURER)
Prerna Kadam
Bradley Spencer-Dene
Professor EMAD RAKHA Emad.Rakha@nottingham.ac.uk
PROFESSOR OF BREAST CANCER PATHOLOGY
Professor MOHAMMAD ILYAS mohammad.ilyas@nottingham.ac.uk
PROFESSOR OF PATHOLOGY
Dr ABDOLRAHMAN SHAMS-NATERI a.nateri@nottingham.ac.uk
ASSOCIATE PROFESSOR
Citation
Almozyan, S., Babaei-Jadidi, R., Aljohani, A., Youssefi, S., Dalleywater, W., Kadam, P., Spencer-Dene, B., Rakha, E., Ilyas, M., & Shams Nateri, A. (2025). Wnt/GSK-3β mediates posttranslational modifications of FLYWCH1 to regulate intestinal epithelial function and tumorigenesis in the colon. Cancer Communications, 45(1), 9-14. https://doi.org/10.1002/cac2.12625
| Journal Article Type | Letter |
|---|---|
| Acceptance Date | Oct 22, 2024 |
| Online Publication Date | Oct 30, 2024 |
| Publication Date | 2025-01 |
| Deposit Date | Nov 1, 2024 |
| Publicly Available Date | Nov 1, 2024 |
| Journal | Cancer Communications |
| Print ISSN | 2523-3548 |
| Electronic ISSN | 2523-3548 |
| Publisher | BioMed Central |
| Peer Reviewed | Peer Reviewed |
| Volume | 45 |
| Issue | 1 |
| Pages | 9-14 |
| DOI | https://doi.org/10.1002/cac2.12625 |
| Keywords | Intestinal tissue regeneration, Colorectal cancer, FLYWCH1 regulatory mechanism, Wnt/b-catenin pathway |
| Public URL | https://nottingham-repository.worktribe.com/output/41195344 |
| Publisher URL | https://onlinelibrary.wiley.com/doi/10.1002/cac2.12625 |
Files
Crosstalk between FLYWCH1 and β-Catenin through Wnt activation and GSK3-β, and its role in maintaining intestinal stem cell homeostasis and tumorigenesis modulation.
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Cancer Communications - 2024 - Almozyan - Wnt GSK ? 3 Mediates Posttranslational Modifications Of FLYWCH1 To Regulate
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Publisher Licence URL
https://creativecommons.org/licenses/by/4.0/
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