Consensus-based technical recommendations for clinical translation of renal T1 and T2 mapping MRI

Semple, Scott I. K.; Dekkers, Ilona A.; de Boer, Anneloes; Sharma, Kaniska; Cox, Eleanor F.; Lamb, Hildo J.; Buckley, David L.; Bane, Octavia; Morris, David M.; Prasad, Pottumarthi V.; Semple, Scott I.K.; Gillis, Keith A.; Hockings, Paul; Buchanan, Charlotte; Wolf, Marcos; Laustsen, Christoffer; Leiner, Tim; Haddock, Bryan; Hoogduin, Johannes M.; Pullens, Pim; Sourbron, Steven; Francis, Susan

Abstract

© 2019, The Author(s). To develop technical recommendations on the acquisition and post-processing of renal longitudinal (T1) and transverse (T2) relaxation time mapping. A multidisciplinary panel consisting of 18 experts in the field of renal T1 and T2 mapping participated in a consensus project, which was initiated by the European Cooperation in Science and Technology Action PARENCHIMA CA16103. Consensus recommendations were formulated using a two-step modified Delphi method. The first survey consisted of 56 items on T1 mapping, of which 4 reached the pre-defined consensus threshold of 75% or higher. The second survey was expanded to include both T1 and T2 mapping, and consisted of 54 items of which 32 reached consensus. Recommendations based were formulated on hardware, patient preparation, acquisition, analysis and reporting. Consensus-based technical recommendations for renal T1 and T2 mapping were formulated. However, there was considerable lack of consensus for renal T1 and particularly renal T2 mapping, to some extent surprising considering the long history of relaxometry in MRI, highlighting key knowledge gaps that require further work. This paper should be regarded as a first step in a long-term evidence-based iterative process towards ever increasing harmonization of scan protocols across sites, to ultimately facilitate clinical implementation.

Citation

Semple, S. I. K., Dekkers, I. A., de Boer, A., Sharma, K., Cox, E. F., Lamb, H. J., Buckley, D. L., Bane, O., Morris, D. M., Prasad, P. V., Semple, S. I., Gillis, K. A., Hockings, P., Buchanan, C., Wolf, M., Laustsen, C., Leiner, T., Haddock, B., Hoogduin, J. M., Pullens, P., …Francis, S. (2020). Consensus-based technical recommendations for clinical translation of renal T1 and T2 mapping MRI. Magnetic Resonance Materials in Physics, Biology and Medicine, 33(1), 163-176. https://doi.org/10.1007/s10334-019-00797-5

• Journal Article Type: Article
• Acceptance Date: Nov 4, 2019
• Online Publication Date: Nov 22, 2019
• Publication Date: 2020-02
• Deposit Date: Jan 2, 2020
• Publicly Available Date: Jan 8, 2020
• Journal: Magnetic Resonance Materials in Physics, Biology and Medicine
• Print ISSN: 0968-5243
• Electronic ISSN: 1352-8661
• Publisher: Springer Verlag
• Peer Reviewed: Peer Reviewed
• Volume: 33
• Issue: 1
• Pages: 163-176
• DOI: https://doi.org/10.1007/s10334-019-00797-5
• Keywords: Biophysics; Radiological and Ultrasound Technology; Radiology Nuclear Medicine and imaging
• Public URL: https://nottingham-repository.worktribe.com/output/3655659
• Publisher URL: https://link.springer.com/article/10.1007/s10334-019-00797-5
• Additional Information: Received: 8 August 2019; Revised: 31 October 2019; Accepted: 4 November 2019; First Online: 22 November 2019; : ; : Author P.H. is director of Imaging at Antaros Medical. Other authors declare no conflict of interest.; : Informed consent was obtained from all individual participants included in the study.