Veterinary use of bacteriophage therapy in intensively-reared livestock

Gigante, Adriano; Atterbury, Robert J

Abstract

Zoonoses are infectious diseases transmitted directly or indirectly between animals and humans. Several important zoonotic pathogens colonize farm animals asymptomatically, which may lead to contamination of the food chain and public health hazards. Moreover, routine sampling of carcasses at retail by government authorities over the past 20 years suggests the prevalence of antibiotic resistance in foodborne pathogens has increased. If this continues, antibiotics may be ineffective against such pathogens in the future and alternative approaches, such as phage therapy, may be necessary. Intensive livestock farming is the only realistic way of meeting the demand for meat from an increasing global population and growth in middle class consumers in developing countries, particularly in Asia. This review elaborates on the use of phages to control zoonotic pathogens in intensively-reared livestock (poultry and pigs).

Citation

Gigante, A., & Atterbury, R. J. (2019). Veterinary use of bacteriophage therapy in intensively-reared livestock. Virology Journal, 16(1), Article 155. https://doi.org/10.1186/s12985-019-1260-3

• Journal Article Type: Review
• Acceptance Date: Nov 22, 2019
• Online Publication Date: Dec 12, 2019
• Publication Date: Dec 12, 2019
• Deposit Date: Dec 22, 2019
• Publicly Available Date: Jan 6, 2020
• Journal: Virology journal
• Electronic ISSN: 1743-422X
• Publisher: Springer Verlag
• Peer Reviewed: Peer Reviewed
• Volume: 16
• Issue: 1
• Article Number: 155
• DOI: https://doi.org/10.1186/s12985-019-1260-3
• Keywords: Virology; Infectious Diseases
• Public URL: https://nottingham-repository.worktribe.com/output/3610494
• Publisher URL: https://virologyj.biomedcentral.com/articles/10.1186/s12985-019-1260-3
• Additional Information: Received: 7 June 2019; Accepted: 22 November 2019; First Online: 12 December 2019; : Not applicable.; : Not applicable.; : The authors declare that they have no competing interests.