Samaah Fathima
Risk factors for the development of Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis, following drug administration: a systematic review and meta-analysis
Fathima, Samaah; Grainge, Matthew J; Wainman, Hannah; Swiderski, Mikolaj; Gran, Sonia
Authors
MATTHEW GRAINGE MATTHEW.GRAINGE@NOTTINGHAM.AC.UK
Associate Professor
Hannah Wainman
MIKOLAJ ANDRZEJ SWIDERSKI MIKOLAJ.SWIDERSKI1@NOTTINGHAM.AC.UK
Research Associate
SONIA GRAN SONIA.GRAN@NOTTINGHAM.AC.UK
Associate Professor
Abstract
The aim of this systematic review was to determine risk factors for the development of Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis (SJS/TEN), following drug administration. The study protocol was registered on PROSPERO. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines were followed. On 17th October 2022, a search, advised by a librarian, was conducted in Medline and EMBASE. Five studies were pooled. We report that HIV and male gender may be risk factors for SJS/TEN however this review was limited by a low number, and quality, of included studies. We conclude a well-designed, large population-based case-control study with an appropriate control group is required to assess risk factors for development of drug-induced SJS/TEN.
Journal Article Type | Article |
---|---|
Acceptance Date | May 13, 2024 |
Online Publication Date | May 15, 2024 |
Publication Date | May 15, 2024 |
Deposit Date | May 22, 2024 |
Publicly Available Date | May 16, 2025 |
Journal | Clinical and Experimental Dermatology |
Print ISSN | 0307-6938 |
Electronic ISSN | 1365-2230 |
Publisher | Wiley |
Peer Reviewed | Peer Reviewed |
DOI | https://doi.org/10.1093/ced/llae183 |
Public URL | https://nottingham-repository.worktribe.com/output/35151850 |
Publisher URL | https://academic.oup.com/ced/advance-article-abstract/doi/10.1093/ced/llae183/7673543?redirectedFrom=fulltext&login=false |
Files
This file is under embargo until May 16, 2025 due to copyright restrictions.
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