Genetic Variation: Harmful Recessive Mutations Have Unexpected Effects on Variation

Brookfield, John F.Y.

Abstract

© 2019 Elsevier Ltd New data are causing the standard model for the effect of selection on linked neutral variation in low recombination regions, combining the effects of background selection and selective sweeps, to be refined to include harmful recessive mutations creating associative overdominance.

Citation

Brookfield, J. F. (2020). Genetic Variation: Harmful Recessive Mutations Have Unexpected Effects on Variation. Current Biology, 30(1), R16-R18. https://doi.org/10.1016/j.cub.2019.11.040

• Journal Article Type: Article
• Acceptance Date: Nov 11, 2019
• Online Publication Date: Jan 6, 2020
• Publication Date: Feb 6, 2020
• Deposit Date: Dec 3, 2019
• Publicly Available Date: Jan 7, 2021
• Journal: Current Biology
• Print ISSN: 0960-9822
• Electronic ISSN: 1879-0445
• Publisher: Elsevier (Cell Press)
• Peer Reviewed: Not Peer Reviewed
• Volume: 30
• Issue: 1
• Pages: R16-R18
• DOI: https://doi.org/10.1016/j.cub.2019.11.040
• Keywords: General Biochemistry, Genetics and Molecular Biology; General Agricultural and Biological Sciences
• Public URL: https://nottingham-repository.worktribe.com/output/3464524
• Publisher URL: https://www.sciencedirect.com/science/article/pii/S0960982219315106?via%3Dihub
• Additional Information: This article is maintained by: Elsevier; Article Title: Genetic Variation: Harmful Recessive Mutations Have Unexpected Effects on Variation; Journal Title: Current Biology; CrossRef DOI link to publisher maintained version: https://doi.org/10.1016/j.cub.2019.11.040; CrossRef DOI link to the associated document: https://doi.org/10.1016/j.cub.2019.11.063; Content Type: article; Copyright: © 2019 Elsevier Ltd.