Iron(II)-catalyzed hydroamination of isocyanates

South, Amy J.; Geer, Ana M.; Taylor, Laurence J.; Sharpe, Helen R.; Lewis, William; Blake, Alexander J.; Kays, Deborah L.

Abstract

A two-coordinate Fe(II) m-terphenyl complex acts as a precatalyst for the hydroamination of isocyanates, affording urea and biuret derivatives, with product selectivity accomplished via modification of the reaction conditions. Using a more nucleophilic amine facilitates the insertion of up to four isocyanates into the N–H bond, affording triuret and tetrauret derivatives.

• Journal Article Type: Article
• Acceptance Date: Sep 25, 2019
• Online Publication Date: Oct 7, 2019
• Publication Date: Nov 11, 2019
• Deposit Date: Oct 11, 2019
• Publicly Available Date: Oct 11, 2019
• Journal: Organometallics
• Print ISSN: 0276-7333
• Electronic ISSN: 1520-6041
• Publisher: American Chemical Society
• Peer Reviewed: Peer Reviewed
• Volume: 38
• Issue: 21
• Pages: 4115-4120
• DOI: https://doi.org/10.1021/acs.organomet.9b00393
• Keywords: Physical and Theoretical Chemistry; Inorganic Chemistry; Organic Chemistry
• Public URL: https://nottingham-repository.worktribe.com/output/2803245
• Publisher URL: https://pubs.acs.org/doi/10.1021/acs.organomet.9b00393