Iron(II)-catalyzed hydroamination of isocyanates

South, Amy J.; Geer, Ana M.; Taylor, Laurence J.; Sharpe, Helen R.; Lewis, William; Blake, Alexander J.; Kays, Deborah L.

Abstract

A two-coordinate Fe(II) m-terphenyl complex acts as a precatalyst for the hydroamination of isocyanates, affording urea and biuret derivatives, with product selectivity accomplished via modification of the reaction conditions. Using a more nucleophilic amine facilitates the insertion of up to four isocyanates into the N–H bond, affording triuret and tetrauret derivatives.

Citation

South, A. J., Geer, A. M., Taylor, L. J., Sharpe, H. R., Lewis, W., Blake, A. J., & Kays, D. L. (2019). Iron(II)-catalyzed hydroamination of isocyanates. Organometallics, 38(21), 4115-4120. https://doi.org/10.1021/acs.organomet.9b00393

• Journal Article Type: Article
• Acceptance Date: Sep 25, 2019
• Online Publication Date: Oct 7, 2019
• Publication Date: Nov 11, 2019
• Deposit Date: Oct 11, 2019
• Publicly Available Date: Oct 11, 2019
• Journal: Organometallics
• Print ISSN: 0276-7333
• Electronic ISSN: 1520-6041
• Publisher: American Chemical Society
• Peer Reviewed: Peer Reviewed
• Volume: 38
• Issue: 21
• Pages: 4115-4120
• DOI: https://doi.org/10.1021/acs.organomet.9b00393
• Keywords: Physical and Theoretical Chemistry; Inorganic Chemistry; Organic Chemistry
• Public URL: https://nottingham-repository.worktribe.com/output/2803245
• Publisher URL: https://pubs.acs.org/doi/10.1021/acs.organomet.9b00393
• Contract Date: Oct 11, 2019