Omer Elneima
Cohort Profile: Post-hospitalisation COVID-19 study (PHOSP-COVID)
Elneima, Omer; McAuley, Hamish J C; Leavy, Olivia C; Chalmers, James D; Horsley, Alex; Ho, Ling-Pei; Marks, Michael; Poinasamy, Krisnah; Raman, Betty; Shikotra, Aarti; Singapuri, Amisha; Sereno, Marco; Harris, Victoria C; Houchen-Wolloff, Linzy; Saunders, Ruth M; Greening, Neil J; Richardson, Matthew; Quint, Jennifer K; Briggs, Andrew; Docherty, Annemarie B; Kerr, Steven; Harrison, Ewen M; Lone, Nazir I; Thorpe, Mathew; Heaney, Liam G; Lewis, Keir E; Aul, Raminder; Beirne, Paul; Bolton, Charlotte E; Brown, Jeremy S; Choudhury, Gourab; Diar Bakerly, Nawar; Easom, Nicholas; Echevarria, Carlos; Fuld, Jonathan; Hart, Nick; Hurst, John R; Jones, Mark G; Parekh, Dhruv; Pfeffer, Paul E; Rahman, Najib M; Rowland-Jones, Sarah L; Thompson, AA Roger; Jolley, Caroline; Shah, Ajay M; Wootton, Dan G; Chalder, Trudie; Davies, Melanie J; De Soyza, Anthony; Geddes, John R; Greenhalf, William; Heller, Simon; Howard, Luke S; Jacob, Joseph; Jenkins, R Gisli; Lord, Janet M; Man, William D-C; McCann, Gerry...
Authors
Hamish J C McAuley
Olivia C Leavy
James D Chalmers
Alex Horsley
Ling-Pei Ho
Michael Marks
Krisnah Poinasamy
Betty Raman
Aarti Shikotra
Amisha Singapuri
Marco Sereno
Victoria C Harris
Linzy Houchen-Wolloff
Ruth M Saunders
Neil J Greening
Matthew Richardson
Jennifer K Quint
Andrew Briggs
Annemarie B Docherty
Steven Kerr
Ewen M Harrison
Nazir I Lone
Mathew Thorpe
Liam G Heaney
Keir E Lewis
Raminder Aul
Paul Beirne
Professor CHARLOTTE BOLTON charlotte.bolton@nottingham.ac.uk
Professor of Respiratory Medicine
Jeremy S Brown
Gourab Choudhury
Nawar Diar Bakerly
Nicholas Easom
Carlos Echevarria
Jonathan Fuld
Nick Hart
John R Hurst
Mark G Jones
Dhruv Parekh
Paul E Pfeffer
Najib M Rahman
Sarah L Rowland-Jones
AA Roger Thompson
Caroline Jolley
Ajay M Shah
Dan G Wootton
Trudie Chalder
Melanie J Davies
Anthony De Soyza
John R Geddes
William Greenhalf
Simon Heller
Luke S Howard
Joseph Jacob
R Gisli Jenkins
Janet M Lord
William D-C Man
Gerry P McCann
Stefan Neubauer
Peter JM Openshaw
Joanna C Porter
Matthew J Rowland
Janet T Scott
Malcolm G Semple
Sally J Singh
David C Thomas
Mark Toshner
Aziz Sheikh
Chris E Brightling
Louise v Wain
Rachael A Evans
on behalf of the PHOSP-COVID Collaborative Group
Abstract
PHOSP-COVID is a national UK multi-centre cohort study of patients who were hospitalised for COVID-19 and subsequently discharged.
PHOSP-COVID was established to investigate the medium- and long-term sequelae of severe COVID-19 requiring hospitalisation, understand the underlying mechanisms of these sequelae, evaluate the medium- and long-term effects of COVID-19 treatments, and to serve as a platform to enable future studies, including clinical trials.
Data collected covered a wide range of physical measures, biological samples, and Patient Reported Outcome Measures (PROMs).
Participants could join the cohort either in Tier 1 only with remote data collection using hospital records, a PROMs app and postal saliva sample for DNA, or in Tier 2 where they were invited to attend two specific research visits for further data collection and biological research sampling. These research visits occurred at five (range 2-7) months and 12 (range 10-14) months post-discharge. Participants could also participate in specific nested studies (Tier 3) at selected sites.
All participants were asked to consent to further follow-up for 25 years via linkage to their electronic healthcare records and to be re-contacted for further research.
In total, 7935 participants were recruited from 83 UK sites: 5238 to Tier 1 and 2697 to Tier 2, between August 2020 and March 2022.
Cohort data are held in a Trusted Research Environment and samples stored in a central biobank. Data and samples can be accessed upon request and subject to approvals.
Citation
Elneima, O., McAuley, H. J. C., Leavy, O. C., Chalmers, J. D., Horsley, A., Ho, L., …on behalf of the PHOSP-COVID Collaborative Group. Cohort Profile: Post-hospitalisation COVID-19 study (PHOSP-COVID)
Working Paper Type | Working Paper |
---|---|
Deposit Date | Feb 29, 2024 |
Publicly Available Date | Feb 29, 2024 |
Public URL | https://nottingham-repository.worktribe.com/output/20566993 |
Publisher URL | https://www.medrxiv.org/content/10.1101/2023.05.08.23289442v1 |
Files
Cohort Profile: Post-hospitalisation COVID-19 study (PHOSP-COVID)
(805 Kb)
PDF
Licence
https://creativecommons.org/licenses/by/4.0/
Publisher Licence URL
https://creativecommons.org/licenses/by/4.0/
You might also like
Age-dependent elastin degradation is enhanced in chronic obstructive pulmonary disease
(2016)
Journal Article
Pulmonary arterial response to hypoxia in survivors of chronic lung disease of prematurity
(2015)
Journal Article
Downloadable Citations
About Repository@Nottingham
Administrator e-mail: discovery-access-systems@nottingham.ac.uk
This application uses the following open-source libraries:
SheetJS Community Edition
Apache License Version 2.0 (http://www.apache.org/licenses/)
PDF.js
Apache License Version 2.0 (http://www.apache.org/licenses/)
Font Awesome
SIL OFL 1.1 (http://scripts.sil.org/OFL)
MIT License (http://opensource.org/licenses/mit-license.html)
CC BY 3.0 ( http://creativecommons.org/licenses/by/3.0/)
Powered by Worktribe © 2024
Advanced Search