Lung cancer screening: does pulmonary nodule detection affect a range of smoking behaviours?

Clark, Marcia E.; Young, Ben; Bedford, Laura E.; Robertson, John F.R.; das Nair, Roshan; Vedhara, Kavita; Sullivan, Francis; Mair, Frances S.; Schembri, Stuart; Littleford, Roberta C.; Kendrick, Denise

Abstract

Background
Lung cancer screening can reduce lung cancer mortality by 20%. Screen-detected abnormalities may provide teachable moments for smoking cessation. This study assesses impact of pulmonary nodule detection on smoking behaviours within the first UK trial of a novel auto-antibody test, followed by chest x-ray and serial CT scanning for early detection of lung cancer (Early Cancer Detection Test-Lung Cancer Scotland Study).
Methods
Test-positive participants completed questionnaires on smoking behaviours at baseline, 1, 3 and 6 months. Logistic regression compared outcomes between nodule (n=95) and normal CT groups (n=174) at 3 and 6 months follow-up.
Results
No significant differences were found between the nodule and normal CT groups for any smoking behaviours and odds ratios comparing the nodule and normal CT groups did not vary significantly between 3 and 6 months. There was some evidence the nodule group were more likely to report significant others wanted them to stop smoking than the normal CT group (OR across 3 and 6 month time points: 3.04, 95%CI 0.95, 9.73; p=0.06).
Conclusion
Pulmonary nodule detection during lung cancer screening has little impact on smoking behaviours. Further work should explore whether lung cancer screening can impact on perceived social pressure and promote smoking cessation.

Citation

Clark, M. E., Young, B., Bedford, L. E., Robertson, J. F., das Nair, R., Vedhara, K., Sullivan, F., Mair, F. S., Schembri, S., Littleford, R. C., & Kendrick, D. (2019). Lung cancer screening: does pulmonary nodule detection affect a range of smoking behaviours?. Journal of Public Health, 41(3), 600-608. https://doi.org/10.1093/pubmed/fdy158

• Journal Article Type: Article
• Acceptance Date: Aug 20, 2018
• Online Publication Date: Sep 29, 2018
• Publication Date: Sep 30, 2019
• Deposit Date: Aug 21, 2018
• Publicly Available Date: Sep 30, 2019
• Journal: Journal of Public Health
• Print ISSN: 1741-3842
• Electronic ISSN: 1741-3850
• Publisher: Oxford University Press
• Peer Reviewed: Peer Reviewed
• Volume: 41
• Issue: 3
• Pages: 600-608
• DOI: https://doi.org/10.1093/pubmed/fdy158
• Keywords: lung cancer screening, pulmonary nodules, smoking behaviour
• Public URL: https://nottingham-repository.worktribe.com/output/1041749
• Publisher URL: https://academic.oup.com/jpubhealth/article/41/3/600/5110542
• Additional Information: This is a pre-copyedited, author-produced version of an article accepted for publication in Journal of Public Health following peer review. The version of record Marcia E Clark, Ben Young, Laura E Bedford, Roshan das Nair, John F R Robertson, Kavita Vedhara, Francis Sullivan, Frances S Mair, Stuart Schembri, Roberta C Littleford, Denise Kendrick; Lung cancer screening: does pulmonary nodule detection affect a range of smoking behaviours?, Journal of Public Health, , fdy158 is available online at: https://doi.org/10.1093/pubmed/fdy158
• Contract Date: Aug 21, 2018