Outputs (6)

Mineral Supplements in Ageing (2024)
Book Chapter
Welham, S., Rose, P., Kirk, C., Coneyworth, L., & Avery, A. (2024). Mineral Supplements in Ageing. In V. I. Korolchuk, & J. R. Harris (Eds.), Biochemistry and Cell Biology of Ageing: Part V, Anti-Ageing Interventions (269-306). Springer. https://doi.org/10.1007/978-3-031-66768-8_13

With advancing age, achievement of dietary adequacy for all nutrients is increasingly difficult and this is particularly so for minerals. Various factors impede mineral acquisition and absorption including reduced appetite, depressed gastric acid pro... Read More about Mineral Supplements in Ageing.

Mineral Supplements in Aging (2024)
Book Chapter
Welham, S., Rose, P., Coneyworth, L., Avery, A., & Kirk, C. (2024). Mineral Supplements in Aging. In V. I. Korolchuk, & J. R. Harris (Eds.), Biochemistry and Cell Biology of Ageing: Part V, Anti-ageing Interventions (269-306). Springer Nature

With advancing age, achievement of dietary adequacy for all nutrients is increasingly difficult and this is particularly so for minerals. Various factors impede mineral acquisition and absorption including reduced appetite, depressed gastric acid pro... Read More about Mineral Supplements in Aging.

A novel small molecule ZYZ384 targeting SMYD3 for hepatocellular carcinoma via reducing H3K4 trimethylation of the Rac1 promoter (2024)
Journal Article
Ding, Q., Cai, J., Jin, L., Hu, W., Song, W., Rose, P., Tang, Z., Zhan, Y., Bao, L., Lei, W., & Zhu, Y. Z. (2024). A novel small molecule ZYZ384 targeting SMYD3 for hepatocellular carcinoma via reducing H3K4 trimethylation of the Rac1 promoter. MedComm, 5(10), Article e711. https://doi.org/10.1002/mco2.711

SMYD3 (SET and MYND domain-containing 3) is a histone lysine methyltransferase highly expressed in different types of cancer(s) and is a promising epigenetic target for developing novel antitumor therapeutics. No selective inhibitors for this protein... Read More about A novel small molecule ZYZ384 targeting SMYD3 for hepatocellular carcinoma via reducing H3K4 trimethylation of the Rac1 promoter.

Magnolol Loaded Polydopamine-Chitosan Coated pH-responsive Nanoparticles for Alleviation of Ulcerative Colitis (2024)
Journal Article
Mu, G., Peng, F., Zhang, Z., M. Brameld, J., Rose, P., Yang, X., Jiang, Z.-J., He, X., & Tang, B. (2024). Magnolol Loaded Polydopamine-Chitosan Coated pH-responsive Nanoparticles for Alleviation of Ulcerative Colitis. Journal of Drug Delivery Science and Technology, 101(Part A), Article 106151. https://doi.org/10.1016/j.jddst.2024.106151

This study designed and developed a novel three-layer electrostatic, slow-releasing nanoparticle drug delivery system for the treatment of ulcerative colitis. The nanoparticles were composed of layers of zein-based polydopamine, chitosan and cellulos... Read More about Magnolol Loaded Polydopamine-Chitosan Coated pH-responsive Nanoparticles for Alleviation of Ulcerative Colitis.

Evaluation of food allergen information, labelling and unintended food allergen presence in imported prepacked foods and drinks purchased online in the UK (2024)
Journal Article
James, C. A., Welham, S., & Rose, P. (2024). Evaluation of food allergen information, labelling and unintended food allergen presence in imported prepacked foods and drinks purchased online in the UK. Food Control, 162, Article 110462. https://doi.org/10.1016/j.foodcont.2024.110462

Consumers have wide access to global food and drink products online and in store that require food allergen information and labelling. Frequent food and drink product recalls occur UK and worldwide due to incorrect labelling of food allergens and the... Read More about Evaluation of food allergen information, labelling and unintended food allergen presence in imported prepacked foods and drinks purchased online in the UK.

Salivary iodide status as a measure of whole body iodine homeostasis? (2024)
Journal Article
Alsaeedi, E. E., Rose, P., & Welham, S. J. (2024). Salivary iodide status as a measure of whole body iodine homeostasis?. British Journal of Nutrition, 131(10), 1740-1753. https://doi.org/10.1017/S000711452400031X

Iodine is a trace element required to produce the thyroid hormones, which are critical for development, growth and metabolism. To ensure appropriate population iodine nutrition, convenient and accurate methods of monitoring are necessary. Current m... Read More about Salivary iodide status as a measure of whole body iodine homeostasis?.