Outputs (720)

Impact of altered cell wall composition on saccharification efficiency in stem tissue of Arabidopsis RABA GTPase-deficient knockout mutants (2015)
Journal Article
Lunn, D., Ibbett, R., Tucker, G. A., & Lycett, G. W. (2015). Impact of altered cell wall composition on saccharification efficiency in stem tissue of Arabidopsis RABA GTPase-deficient knockout mutants. BioEnergy Research, 8(3), https://doi.org/10.1007/s12155-015-9599-9

Use of biomass for second-generation biofuel production is severely hindered by the inherent recalcitrance of the plant cell wall to digestion. Trafficking is crucial for compartmentalisation within the cell. This process is partly regulated by small... Read More about Impact of altered cell wall composition on saccharification efficiency in stem tissue of Arabidopsis RABA GTPase-deficient knockout mutants.

Sodium alginate decreases the permeability of intestinal mucus (2015)
Journal Article
Mackie, A. R., Macierzanka, A., Aarak, K., Rigby, N. M., Parker, R., Channell, G. A., …Bajka, B. H. (2016). Sodium alginate decreases the permeability of intestinal mucus. Food Hydrocolloids, 52, https://doi.org/10.1016/j.foodhyd.2015.08.004

In the small intestine the nature of the environment leads to a highly heterogeneous mucus layer primarily composed of the MUC2 mucin. We set out to investigate whether the soluble dietary fibre sodium alginate could alter the permeability of the muc... Read More about Sodium alginate decreases the permeability of intestinal mucus.

Evaluation of diffusion coefficients by means of an approximate steady-state condition in sedimentation velocity distributions (2015)
Journal Article
Scott, D. J., Harding, S. E., & Winzor, D. J. (2015). Evaluation of diffusion coefficients by means of an approximate steady-state condition in sedimentation velocity distributions. Analytical Biochemistry, 490, https://doi.org/10.1016/j.ab.2015.08.017

This investigation examined the feasibility of manipulating the rotor speed in sedimentation velocity experiments to spontaneously generate an approximate steady-state condition where the extent of diffusional spreading is matched exactly by the boun... Read More about Evaluation of diffusion coefficients by means of an approximate steady-state condition in sedimentation velocity distributions.

Crystal structures of the extracellular domain from PepT1 and PepT2 provide novel insights into mammalian pPeptide transport (2015)
Journal Article
Beale, J. H., Parker, J. L., Samsudin, F., Barrett, A. L., Senan, A., Bird, L. E., …Newstead, S. (2015). Crystal structures of the extracellular domain from PepT1 and PepT2 provide novel insights into mammalian pPeptide transport. Structure, 23(10), https://doi.org/10.1016/j.str.2015.07.016

Mammals obtain nitrogen via the uptake of di- and tri-peptides in the gastrointestinal tract through the action of PepT1 and PepT2, which are members of the POT family of proton-coupled oligopeptide transporters. PepT1 and PepT2 also play an importan... Read More about Crystal structures of the extracellular domain from PepT1 and PepT2 provide novel insights into mammalian pPeptide transport.

Ultracentrifuge Methods for the Analysis of Polysaccharides, Glycoconjugates, and Lignins (2015)
Book Chapter
Harding, S. E., Adams, G. G., Almutairi, F., Alzahrani, Q., Erten, T., Samil Kök, M., & Gillis, R. B. (2015). Ultracentrifuge Methods for the Analysis of Polysaccharides, Glycoconjugates, and Lignins. In Analytical Ultracentrifugation (391-439). Academic Press. https://doi.org/10.1016/bs.mie.2015.06.043

Although like proteins, polysaccharides are synthesized by enzymes, unlike proteins there is no template. This means that they are polydisperse, do not generally have compact folded structures, and are often very large with greater nonideality behavi... Read More about Ultracentrifuge Methods for the Analysis of Polysaccharides, Glycoconjugates, and Lignins.

Primordial germ cells: the first cell lineage or the last cells standing? (2015)
Journal Article
Johnson, A. D., & Alberio, R. (in press). Primordial germ cells: the first cell lineage or the last cells standing?. Development, 142, https://doi.org/10.1242/dev.113993

Embryos of many animal models express germ line determinants that suppress transcription and mediate early germ line commitment, which occurs before the somatic cell lineages are established. However, not all animals segregate their germ line in this... Read More about Primordial germ cells: the first cell lineage or the last cells standing?.

The MYB36 transcription factor orchestrates Casparian strip formation (2015)
Journal Article
Kamiya, T., Borghi, M., Wang, P., Danku, J., Kalmbach, L., Hosmani, P. S., …Salt, D. E. (2015). The MYB36 transcription factor orchestrates Casparian strip formation. Proceedings of the National Academy of Sciences, 112(33), https://doi.org/10.1073/pnas.1507691112

The endodermis in roots acts as a selectivity filter for nutrient and water transport essential for growth and development. This selectivity is enabled by the formation of lignin-based Casparian strips. Casparian strip formation is initiated by the l... Read More about The MYB36 transcription factor orchestrates Casparian strip formation.

Screening of non- Saccharomyces cerevisiae strains for tolerance to formic acid in bioethanol fermentation (2015)
Journal Article
Oshoma, C. E., Greetham, D., Louis, E. J., Smart, K. A., Phister, T. G., Powell, C., & Du, C. (2015). Screening of non- Saccharomyces cerevisiae strains for tolerance to formic acid in bioethanol fermentation. PLoS ONE, 10(8), Article e0135626. https://doi.org/10.1371/journal.pone.0135626

Formic acid is one of the major inhibitory compounds present in hydrolysates derived from lignocellulosic materials, the presence of which can significantly hamper the efficiency of converting available sugars into bioethanol. This study investigated... Read More about Screening of non- Saccharomyces cerevisiae strains for tolerance to formic acid in bioethanol fermentation.

Replacement of soya bean meal with peas and faba beans in growing/finishing pig diets: Effect on performance, carcass composition and nutrient excretion (2015)
Journal Article
Houdijk, J., White, G., White, G. A., Smith, L., Houdijk, J., Homer, D., …Wiseman, J. (2015). Replacement of soya bean meal with peas and faba beans in growing/finishing pig diets: Effect on performance, carcass composition and nutrient excretion. Animal Feed Science and Technology, 209, 202-210. https://doi.org/10.1016/j.anifeedsci.2015.08.005

There is now an increasing debate about the viability of using temperate-grown legumes in pig diets as a potential replacement for imported soya bean meal (SBM) and this is due to food security, sustainability and environmental concerns. Two trials w... Read More about Replacement of soya bean meal with peas and faba beans in growing/finishing pig diets: Effect on performance, carcass composition and nutrient excretion.

Biophysical analysis of a lethal laminin alpha-1 mutation reveals altered self-interaction (2015)
Journal Article
Patel, T. R., Nikodemus, D., Besong, T. M., Reuten, R., Meier, M., Harding, S. E., …Stetefeld, J. (2016). Biophysical analysis of a lethal laminin alpha-1 mutation reveals altered self-interaction. Matrix Biology, 49, https://doi.org/10.1016/j.matbio.2015.06.005

Laminins are key basement membrane molecules that influence several biological activities and are linked to a number of diseases. They are secreted as heterotrimeric proteins consisting of one α, one β, and one γ chain, followed by their assembly int... Read More about Biophysical analysis of a lethal laminin alpha-1 mutation reveals altered self-interaction.