Outputs (128)

Magnetic Retrieval of Encapsulated Beta Cell Transplants from Diabetic Mice Using Dual-Function MRI Visible and Retrievable Microcapsules (2020)
Journal Article
Delcassian, D., Luzhansky, I., Spanoudaki, V., Bochenek, M., McGladrigan, C., Nguyen, A., …Anderson, D. G. (2020). Magnetic Retrieval of Encapsulated Beta Cell Transplants from Diabetic Mice Using Dual-Function MRI Visible and Retrievable Microcapsules. Advanced Materials, 32(16), Article 1904502. https://doi.org/10.1002/adma.201904502

© 2020 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim Encapsulated beta cell transplantation offers a potential cure for a subset of diabetic patients. Once transplanted, beta cell grafts can help to restore glycemic control; however, locating and retr... Read More about Magnetic Retrieval of Encapsulated Beta Cell Transplants from Diabetic Mice Using Dual-Function MRI Visible and Retrievable Microcapsules.

Disordered protein-graphene oxide co-assembly and supramolecular biofabrication of functional fluidic devices (2020)
Journal Article
Wu, Y., Okesola, B. O., Xu, J., Korotkin, I., Berado, A., Corridori, I., …Mata, A. (2020). Disordered protein-graphene oxide co-assembly and supramolecular biofabrication of functional fluidic devices. Nature Communications, 11(1), Article 1182. https://doi.org/10.1038/s41467-020-14716-z

Supramolecular chemistry offers an exciting opportunity to assemble materials with molecular precision. However, there remains an unmet need to turn molecular self-assembly into functional materials and devices. Harnessing the inherent properties of... Read More about Disordered protein-graphene oxide co-assembly and supramolecular biofabrication of functional fluidic devices.

Effect of acute and short-term dietary fat ingestion on postprandial skeletal muscle protein synthesis rates in middle-aged, overweight, and obese men (2020)
Journal Article
Tsintzas, K., Jones, R., Pabla, P., Mallinson, J., Barrett, D. A., Kim, D. H., …Stephens, F. B. (2020). Effect of acute and short-term dietary fat ingestion on postprandial skeletal muscle protein synthesis rates in middle-aged, overweight, and obese men. AJP - Endocrinology and Metabolism, 318(3), E417-E429. https://doi.org/10.1152/ajpendo.00344.2019

Muscle anabolic resistance to dietary protein is associated with obesity and insulin resistance. However, the contribution of excess consumption of fat to anabolic resistance is not well studied. The aim of these studies was to test the hypothesis th... Read More about Effect of acute and short-term dietary fat ingestion on postprandial skeletal muscle protein synthesis rates in middle-aged, overweight, and obese men.

Evaluation of a community pharmacy-led test-and-treat service for women with uncomplicated lower urinary tract infection in England (2020)
Journal Article
Thornley, T., Kirkdale, C. L., Beech, E., Howard, P., & Wilson, P. (2020). Evaluation of a community pharmacy-led test-and-treat service for women with uncomplicated lower urinary tract infection in England. JAC-Antimicrobial Resistance, 2(1), Article dlaa010. https://doi.org/10.1093/jacamr/dlaa010

Background: Uncomplicated lower urinary tract infections (UTIs) are common in women consulting primary healthcare, taking up GP resources. Delayed consultation can increase the risk of serious infections such as pyelonephritis or bacteraemia. Objecti... Read More about Evaluation of a community pharmacy-led test-and-treat service for women with uncomplicated lower urinary tract infection in England.

A Simple Polymicrobial Biofilm Keratinocyte Colonization Model for Exploring Interactions Between Commensals, Pathogens and Antimicrobials (2020)
Journal Article
Jordana-Lluch, E., Garcia, V., Kingdon, A. D. H., Singh, N., Alexander, C., Williams, P., & Hardie, K. R. (2020). A Simple Polymicrobial Biofilm Keratinocyte Colonization Model for Exploring Interactions Between Commensals, Pathogens and Antimicrobials. Frontiers in Microbiology, 11, Article 291. https://doi.org/10.3389/fmicb.2020.00291

© 2020 Jordana-Lluch, Garcia, Kingdon, Singh, Alexander, Williams and Hardie. Skin offers protection against external insults, with the skin microbiota playing a crucial defensive role against pathogens that gain access when the skin barrier is breac... Read More about A Simple Polymicrobial Biofilm Keratinocyte Colonization Model for Exploring Interactions Between Commensals, Pathogens and Antimicrobials.

Development of a Neutral Diketopyrrolopyrrole Phosphine Oxide for the Selective Bioimaging of Mitochondria at the Nanomolar Level (2020)
Journal Article
Abelha, T. F., Morris, G., Lima, S. M., Andrade, L. H. C., McLean, A. J., Alexander, C., …McHugh, C. J. (2020). Development of a Neutral Diketopyrrolopyrrole Phosphine Oxide for the Selective Bioimaging of Mitochondria at the Nanomolar Level. Chemistry - A European Journal, 26(14), 3173-3180. https://doi.org/10.1002/chem.201905634

© 2020 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim Development of novel bioimaging materials that exhibit organelle specific accumulation continues to be at the forefront of research interests and efforts. Among the various subcellular organelles, m... Read More about Development of a Neutral Diketopyrrolopyrrole Phosphine Oxide for the Selective Bioimaging of Mitochondria at the Nanomolar Level.

Development of Pyrazolo[3,4- d]pyrimidine Kinase Inhibitors as Potential Clinical Candidates for Glioblastoma Multiforme (2020)
Journal Article
Greco, C., Taresco, V., Pearce, A. K., Vasey, C. E., Smith, S., Rahman, R., …Schenone, S. (2020). Development of Pyrazolo[3,4- d]pyrimidine Kinase Inhibitors as Potential Clinical Candidates for Glioblastoma Multiforme. ACS Medicinal Chemistry Letters, 11(5), 657-663. https://doi.org/10.1021/acsmedchemlett.9b00530

Glioblastoma multiforme (GBM) is the most aggressive primary brain tumor. Residual cells at the tumor margin are responsible for up to 85% of GBM recurrences after standard treatment. Despite this evidence, the identification of compounds active on t... Read More about Development of Pyrazolo[3,4- d]pyrimidine Kinase Inhibitors as Potential Clinical Candidates for Glioblastoma Multiforme.

Four-wave-mixing microscopy reveals non- colocalisation between gold nanoparticles and fluorophore conjugates inside cells (2020)
Journal Article
Giannakopoulou, N., Williams, J. B., Moody, P. R., Sayers, E. J., Magnusson, J. P., Pope, I., …Borri, P. (2020). Four-wave-mixing microscopy reveals non- colocalisation between gold nanoparticles and fluorophore conjugates inside cells. Nanoscale, 12(7), 4622-4635. https://doi.org/10.1039/b000000x

Gold nanoparticles have been researched for many biomedical applications in diagnostics, ther-anostics, and as drug delivery systems. When conjugated to fluorophores, their interaction with biological cells can be studied in situ and real time using... Read More about Four-wave-mixing microscopy reveals non- colocalisation between gold nanoparticles and fluorophore conjugates inside cells.

Development of an in vitro system to study the interactions of aerosolized drugs with pulmonary mucus (2020)
Journal Article
Alqahtani, S., Roberts, C. J., Stolnik, S., & Bosquillon, C. (2020). Development of an in vitro system to study the interactions of aerosolized drugs with pulmonary mucus. Pharmaceutics, 12(2), https://doi.org/10.3390/pharmaceutics12020145

© 2020 by the authors. Licensee MDPI, Basel, Switzerland. Mucus is the first biological component inhaled drugs encounter on their journey towards their pharmacological target in the upper airways. Yet, how mucus may influence drug disposition and ef... Read More about Development of an in vitro system to study the interactions of aerosolized drugs with pulmonary mucus.

Four-wave-mixing microscopy reveals non-colocalisation between gold nanoparticles and fluorophore conjugates inside cells (2020)
Journal Article
Jones, A. T., Giannakopoulou, N., Borri, P., Williams, J. B., Watson, P., Moody, P. R., …Pope, I. (2020). Four-wave-mixing microscopy reveals non-colocalisation between gold nanoparticles and fluorophore conjugates inside cells. Nanoscale, 12(7), 4622-4635. https://doi.org/10.1039/c9nr08512b

Gold nanoparticles have been researched for many biomedical applications in diagnostics, theranostics, and as drug delivery systems. When conjugated to fluorophores, their interaction with biological cells can be studied in situ and real time using f... Read More about Four-wave-mixing microscopy reveals non-colocalisation between gold nanoparticles and fluorophore conjugates inside cells.