Outputs (133)

Enhanced distance-dependent fluorescence quenching using size tuneable core shell silica nanoparticles (2018)
Journal Article
Elsutohy, M. M., Selo, A., Chauhan, V. M., Tendler, S. J., & Aylott, J. W. (2018). Enhanced distance-dependent fluorescence quenching using size tuneable core shell silica nanoparticles. RSC Advances, 8(62), 35840-35848. https://doi.org/10.1039/C8RA05929B

Silica nanoparticles (SNPs) have been used as favoured platforms for sensor, drug delivery and biological imaging applications, due to their ease of synthesis, size-control and bespoke physico-chemical properties. In this study, we have developed a p... Read More about Enhanced distance-dependent fluorescence quenching using size tuneable core shell silica nanoparticles.

Predicting puberty in partial androgen insensitivity syndrome: use of clinical and functional androgen receptor indices (2018)
Journal Article
Lek, N., Tadokoro-Cuccaro, R., Whitchurch, J. B., Mazumder, B., Miles, H., Prentice, P., …Hughes, I. A. (2018). Predicting puberty in partial androgen insensitivity syndrome: use of clinical and functional androgen receptor indices. EBioMedicine, 36, 401-409. https://doi.org/10.1016/j.ebiom.2018.09.047

Rapid formulation of redox-responsive oligo-?-aminoester polyplexes with siRNA via jet printing (2018)
Journal Article
Lovato, T., Taresco, V., Alazzo, A., Sansone, C., Stolnik, S., Alexander, C., & Conte, C. (2018). Rapid formulation of redox-responsive oligo-?-aminoester polyplexes with siRNA via jet printing. Journal of Materials Chemistry B, 6(41), 6550-6558. https://doi.org/10.1039/C8TB01215F

Here we describe a rapid inkjet formulation method for screening newly-synthesised cationic materials for siRNA delivery into cancer cells. Reduction responsive oligo-?-aminoesters were prepared and evaluated for their ability to condense siRNA into... Read More about Rapid formulation of redox-responsive oligo-?-aminoester polyplexes with siRNA via jet printing.

Developing the global graduate: how first year university students’ narrate their experiences of culture (2018)
Journal Article
Dippold, D., Bridges, S., Eccles, S., & Mullen, E. (2019). Developing the global graduate: how first year university students’ narrate their experiences of culture. Language and Intercultural Communication, 19(4), 313-327. https://doi.org/10.1080/14708477.2018.1526939

Developing global graduates or global citizens is a goal often expressed in university mission statements. This study draws on Amadasi and Holliday's (2017) distinction of block narratives and thread narratives of culture and applies these to intervi... Read More about Developing the global graduate: how first year university students’ narrate their experiences of culture.

Reliability and efficiency evaluation of a community pharmacy dispensing process using a coloured Petri-net approach (2018)
Journal Article
Naybour, M., Remenyte-Prescott, R., & Boyd, M. J. (2019). Reliability and efficiency evaluation of a community pharmacy dispensing process using a coloured Petri-net approach. Reliability Engineering and System Safety, 182, 258-268. https://doi.org/10.1016/j.ress.2018.09.022

© 2018 It has been estimated that European customers visit community pharmacies to access essential primary healthcare around 46 million times every day. Studies of dispensing error rates in community pharmacies have reported error rates of between 0... Read More about Reliability and efficiency evaluation of a community pharmacy dispensing process using a coloured Petri-net approach.

Quantitative prediction of oral bioavailability of a lipophilic antineoplastic drug bexarotene administered in lipidic formulation using a combined in vitro lipolysis/microsomal metabolism approach (2018)
Journal Article
Lee, J. B., Kim, T. H., Feng, W., Choi, H. G., Zgair, A., Shin, S., …Shin, B. S. (2019). Quantitative prediction of oral bioavailability of a lipophilic antineoplastic drug bexarotene administered in lipidic formulation using a combined in vitro lipolysis/microsomal metabolism approach. Pharmaceutical Sciences, 108(2), 1047-1052. https://doi.org/10.1016/j.xphs.2018.09.025

For performance assessment of the lipid-based drug delivery systems (LBDDS), in vitro lipolysis is commonly applied because traditional dissolution tests do not reflect the complicated in vivo micellar formation and solubilisation processes. Much of... Read More about Quantitative prediction of oral bioavailability of a lipophilic antineoplastic drug bexarotene administered in lipidic formulation using a combined in vitro lipolysis/microsomal metabolism approach.

Are we on the right track? Answers from a national survey of Thai graduates’ perceptions during the transition to the 6-year PharmD program (2018)
Journal Article
Suttajit, S., Suwannaprom, P., Supapaan, T., Eakanunkul, S., Tangkiatkumjai, M., Kongkaew, C., …Wongpoowarak, P. (2018). Are we on the right track? Answers from a national survey of Thai graduates’ perceptions during the transition to the 6-year PharmD program. Advances in Medical Education and Practice, 9, 713-722. https://doi.org/10.2147/AMEP.S173014

Purpose: To serve the higher demands of pharmaceutical services, pharmacy education in Thailand has shifted from 5-year BPharm program to 6-year PharmD program with two specialization tracks: pharmaceutical care (PC) and industrial pharmacy (IP). Thi... Read More about Are we on the right track? Answers from a national survey of Thai graduates’ perceptions during the transition to the 6-year PharmD program.

Synthesis, Biological Evaluation of Fluorescent 23-Hydroxybetulinic Acid Probes, and Their Cellular Localization Studies (2018)
Journal Article
Yao, H., Wei, G., Liu, Y., Yao, H., Zhu, Z., Ye, W., …Xu, S. (2018). Synthesis, Biological Evaluation of Fluorescent 23-Hydroxybetulinic Acid Probes, and Their Cellular Localization Studies. ACS Medicinal Chemistry Letters, 9(10), 1030-1034. https://doi.org/10.1021/acsmedchemlett.8b00321

© 2018 American Chemical Society. 23-Hydroxybetulinic acid (23-HBA) is a complex lupane triterpenoid, which has attracted increasing attention as an anticancer agent. However, its detailed mechanism of anticancer action remains elusive so far. To rev... Read More about Synthesis, Biological Evaluation of Fluorescent 23-Hydroxybetulinic Acid Probes, and Their Cellular Localization Studies.

Wireless bioelectronic nanosystems for intracellular communication (2018)
Other
Sanjuán-Alberte, P., Abayzeed, S. A., Fuentes-Domínguez, R., Alea-Reyesd, M. E., Clark, M., Hague, R., …Rawson, F. (2018). Wireless bioelectronic nanosystems for intracellular communication

In order for the field of bioelectronics to make an impact on healthcare, there is an urgent requirement for the development of “wireless” electronic systems to both sense and actuate cell behaviour. Herein we report the first example of an innovativ... Read More about Wireless bioelectronic nanosystems for intracellular communication.

The structure of the deubiquitinase USP15 reveals a misaligned catalytic triad and an open ubiquitin-binding channel (2018)
Journal Article
Ward, S. J., Gratton, H. E., Indrayudha, P., Michavila, C., Mukhopadhyay, R., Maurer, S. K., …Dreveny, I. (2018). The structure of the deubiquitinase USP15 reveals a misaligned catalytic triad and an open ubiquitin-binding channel. Journal of Biological Chemistry, 293(45), 17362-17374. https://doi.org/10.1074/jbc.RA118.003857

© 2018 Ward et al. Ubiquitin-specific protease 15 (USP15) regulates important cellular processes, including transforming growth factor β (TGF-β) signaling, mitophagy, mRNA processing, and innate immune responses; however, structural information on US... Read More about The structure of the deubiquitinase USP15 reveals a misaligned catalytic triad and an open ubiquitin-binding channel.