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Close-range photogrammetry enables documentation of environment-induced deformation of architectural heritage (2015)
Journal Article
Sužiedelytė-Visockienė, J., Bagdžiūnaitė, R., Malys, N., & Maliene, V. (2015). Close-range photogrammetry enables documentation of environment-induced deformation of architectural heritage. Environmental Engineering and Management Journal, 14(6),

Deformation, damage and permanent loss of heritage assets due to various physical and environmental factors has always been a major problem. As the availability of funds for conservation and restoration is limited, the digital documentation of herita... Read More about Close-range photogrammetry enables documentation of environment-induced deformation of architectural heritage.

The role of Cas8 in type I CRISPR interference (2015)
Journal Article
Cass, S., Haas, K., Stoll, B., Alkhnbashi, O., Sharma, K., Urlaub, H., …Bolt, E. (2015). The role of Cas8 in type I CRISPR interference. Bioscience Reports, 35, doi:10.1042/BSR20150043

CRISPR (clustered regularly interspaced short palindromic repeat) systems provide bacteria and archaea with adapt- ive immunity to repel invasive genetic elements. Type I systems use ‘cascade’ [CRISPR-associated (Cas) complex for antiviral defence] r... Read More about The role of Cas8 in type I CRISPR interference.

Contribution of serotonin and dopamine to changes in core body temperature and locomotor activity in rats following repeated administration of mephedrone (2015)
Journal Article
Shortall, S. E., Spicer, C. H., Ebling, F. J., Green, A. R., Fone, K. C., & King, M. V. (2015). Contribution of serotonin and dopamine to changes in core body temperature and locomotor activity in rats following repeated administration of mephedrone. Addiction Biology, doi:10.1111/adb.12283

The psychoactive effects of mephedrone are commonly compared to those of 3,4-methylenedioxymethamphetamine, but because of a shorter duration of action users often employ repeated administration to maintain its psychoactive actions. This study examin... Read More about Contribution of serotonin and dopamine to changes in core body temperature and locomotor activity in rats following repeated administration of mephedrone.

Housing stakeholder preferences for the “soft” features of sustainable and healthy housing design in the UK (2016)
Journal Article
Prochorskaite, A., Couch, C., Malys, N., & Maliene, V. (2016). Housing stakeholder preferences for the “soft” features of sustainable and healthy housing design in the UK. International Journal of Environmental Research and Public Health, 13(1), doi:10.3390/ijerph13010111

It is widely recognised that the quantity and sustainability of new homes in the UK need to increase. However, it is important that sustainable housing is regarded holistically, and not merely in environmental terms, and incorporates elements that en... Read More about Housing stakeholder preferences for the “soft” features of sustainable and healthy housing design in the UK.

Isoaspartate, Carbamoyl phosphate synthase-1, and carbonic anhydrase-III as biomarkers of liver injury (2016)
Journal Article
Carter, W., Vigneswara, V., Newlaczyl, A., Wayne, D., Ahmed, B., Saddington, S., …Kharbanda, K. (2016). Isoaspartate, Carbamoyl phosphate synthase-1, and carbonic anhydrase-III as biomarkers of liver injury. Biochemical and Biophysical Research Communications, 458(3), doi:10.1016/j.bbrc.2015.01.158

We had previously shown that alcohol consumption can induce cellular isoaspartate protein damage via an impairment of the activity of protein isoaspartyl methyltransferase (PIMT), an enzyme that triggers repair of isoaspartate protein damage. To furt... Read More about Isoaspartate, Carbamoyl phosphate synthase-1, and carbonic anhydrase-III as biomarkers of liver injury.

Cas3 is a limiting factor for CRISPR-Cas immunity in Escherichia coli cells lacking H-NS (2016)
Journal Article
Majsec, K., Bolt, E. L., & Ivančić-Baće, I. (in press). Cas3 is a limiting factor for CRISPR-Cas immunity in Escherichia coli cells lacking H-NS. BMC Microbiology, 16(28), doi:10.1186/s12866-016-0643-5

Background: CRISPR-Cas systems provide adaptive immunity to mobile genetic elements in prokaryotes. In many bacteria, including E. coli, a specialized ribonucleoprotein complex called Cascade enacts immunity by “an interference reaction" between CRIS... Read More about Cas3 is a limiting factor for CRISPR-Cas immunity in Escherichia coli cells lacking H-NS.

Non-destructive characterisation of mesenchymal stem cell differentiation using LC-MS-based metabolite footprinting (2016)
Journal Article
Surrati, A., Linforth, R. S., Fisk, I. D., Sottile, V., & Kim, D. (in press). Non-destructive characterisation of mesenchymal stem cell differentiation using LC-MS-based metabolite footprinting. Analyst, 12, doi:10.1039/c6an00170j

Bone regeneration is a complex biological process where major cellular changes take place to support the osteogenic differentiation of mesenchymal bone progenitors. To characterise these biological changes and better understand the pathways regulatin... Read More about Non-destructive characterisation of mesenchymal stem cell differentiation using LC-MS-based metabolite footprinting.

Caffeine alters the behavioural and body temperature responses to mephedrone without causing long-term neurotoxicity in rats (2016)
Journal Article
Shortall, S. E., Green, A. R., Fone, K. C., & King, M. V. (2016). Caffeine alters the behavioural and body temperature responses to mephedrone without causing long-term neurotoxicity in rats. Journal of Psychopharmacology, 30(7), doi:10.1177/0269881116650408

Administration of caffeine with 3,4-methylenedioxymethamphetamine (MDMA) alters the pharmacological properties of MDMA in rats. The current study examined whether caffeine alters the behavioural and neurochemical effects of mephedrone, which has simi... Read More about Caffeine alters the behavioural and body temperature responses to mephedrone without causing long-term neurotoxicity in rats.