Outputs (108)

A Functional Single-Nucleotide Polymorphism Upstream of the Collagen Type III Gene Is Associated with Catastrophic Fracture Risk in Thoroughbred Horses (2023)
Journal Article
Palomino Lago, E., Baird, A., Blott, S. C., McPhail, R. E., Ross, A. C., Durward-Akhurst, S. A., & Guest, D. J. (2024). A Functional Single-Nucleotide Polymorphism Upstream of the Collagen Type III Gene Is Associated with Catastrophic Fracture Risk in Thoroughbred Horses. Animals, 14(1), Article 116. https://doi.org/10.3390/ani14010116

Fractures caused by bone overloading are a leading cause of euthanasia in Thoroughbred racehorses. The risk of fatal fracture has been shown to be influenced by both environmental and genetic factors but, to date, no specific genetic mechanisms under... Read More about A Functional Single-Nucleotide Polymorphism Upstream of the Collagen Type III Gene Is Associated with Catastrophic Fracture Risk in Thoroughbred Horses.

The Toxoplasma protein phosphatase 6 catalytic subunit (TgPP6C) is essential for cell cycle progression and virulence (2023)
Journal Article
Liang, Q. L., Nie, L. B., Elsheikha, H. M., Li, T. T., Sun, L. X., Zhang, Z. W., Wang, M., Fu, B. Q., Zhu, X. Q., & Wang, J. L. (2023). The Toxoplasma protein phosphatase 6 catalytic subunit (TgPP6C) is essential for cell cycle progression and virulence. PLoS Pathogens, 19(12), Article e1011831. https://doi.org/10.1371/journal.ppat.1011831

Protein phosphatases are post-translational regulators of Toxoplasma gondii proliferation, tachyzoite-bradyzoite differentiation and pathogenesis. Here, we identify the putative protein phosphatase 6 (TgPP6) subunits of T. gondii and elucidate their... Read More about The Toxoplasma protein phosphatase 6 catalytic subunit (TgPP6C) is essential for cell cycle progression and virulence.

Improvement of mammary gland health in 81 'sentinel herds' in England and Scotland between 2012 and 2021. (2023)
Journal Article
Leach, K. A., Holsey, H. J., Bradley, A. J., & Green, M. J. (2023). Improvement of mammary gland health in 81 'sentinel herds' in England and Scotland between 2012 and 2021. Veterinary Record, Article e3605. https://doi.org/10.1002/vetr.3605

Background: Achieving a reduction in mastitis in dairy cows is a common industry goal, but there is no recent peer-reviewed record of progress in the UK. Methods: A convenience sample of 125 herds in England and Scotland was recruited based on the qu... Read More about Improvement of mammary gland health in 81 'sentinel herds' in England and Scotland between 2012 and 2021..

The splicing factor SR2 is an important virulence factor of Toxoplasma gondii (2023)
Journal Article
Wu, X.-J., Nanzheng, X.-N., Elsheikha, H. M., Li, T.-T., Kou, Y.-J., & Zhu, X.-Q. (2023). The splicing factor SR2 is an important virulence factor of Toxoplasma gondii. Frontiers in Microbiology, 14, Article 1302512. https://doi.org/10.3389/fmicb.2023.1302512

Serine/arginine-rich (SR) proteins are key factors with important roles in constitutive and alternative splicing (AS) of pre-mRNAs. However, the role of SR splicing factors in the pathogenicity of T. gondii remains largely unexplored. Here, we invest... Read More about The splicing factor SR2 is an important virulence factor of Toxoplasma gondii.

Prospective case study of critical decision making for horses referred for treatment of colic (2023)
Journal Article
Burrell, K., Sutton‐Walker, G., England, G. C. W., Burford, J. H., & Freeman, S. L. (2023). Prospective case study of critical decision making for horses referred for treatment of colic. Veterinary Record, 194(12), Article e3615. https://doi.org/10.1002/vetr.3615

Background
There is limited evidence on factors affecting critical decision making for horses with colic. This study's aim was to describe the assessment and decision making involved in horses referred for management of colic.

Methods
An in-dept... Read More about Prospective case study of critical decision making for horses referred for treatment of colic.

Incorporating biodiversity responses to land use change scenarios for preventing emerging zoonotic diseases in areas of unknown host-pathogen interactions (2023)
Journal Article
Roque, F. D. O., Bellón, B., Guerra, A., Valente-Neto, F., Santos, C. C., Melo, I., Nobre Arcos, A., de Oliveira, A. G., Valle Nunes, A., de Araujo Martins, C., Souza, F. L., Herrera, H., Tavares, L. E. R., Almeida-Gomes, M., Pays, O., Renaud, P.-C., Gomes Barrios, S. P., Yon, L., Bowsher, G., Sullivan, R., …Ochoa-Quintero, J. M. (2023). Incorporating biodiversity responses to land use change scenarios for preventing emerging zoonotic diseases in areas of unknown host-pathogen interactions. Frontiers in Veterinary Science, 10, Article 1229676. https://doi.org/10.3389/fvets.2023.1229676

The need to reconcile food production, the safeguarding of nature, and the protection of public health is imperative in a world of continuing global change, particularly in the context of risks of emerging zoonotic disease (EZD). In this paper, we ex... Read More about Incorporating biodiversity responses to land use change scenarios for preventing emerging zoonotic diseases in areas of unknown host-pathogen interactions.

Ethical challenges experienced by veterinary practitioners in relation to adverse events: Insights from a qualitative study (2023)
Journal Article
Gibson, J., Brennan, M. L., Oxtoby, C., Mossop, L., & White, K. (2023). Ethical challenges experienced by veterinary practitioners in relation to adverse events: Insights from a qualitative study. Veterinary Record, 193(12), Article e3601. https://doi.org/10.1002/vetr.3601

Background
Understanding ethical challenges experienced in relation to adverse events is necessary to inform strategies that optimise patient safety and practitioner wellbeing.

Methods
A qualitative exploration of UK veterinary practitioners’ ex... Read More about Ethical challenges experienced by veterinary practitioners in relation to adverse events: Insights from a qualitative study.

Pseudomonas spp. in Canine Otitis Externa (2023)
Journal Article
Secker, B., Shaw, S., & Atterbury, R. J. (2023). Pseudomonas spp. in Canine Otitis Externa. Microorganisms, 11(11), Article 2650. https://doi.org/10.3390/microorganisms11112650

Canine otitis externa (OE) is a commonly diagnosed condition seen in veterinary practice worldwide. In this review, we discuss the mechanisms of the disease, with a particular focus on the biological characteristics of Pseudomonas aeruginosa and the... Read More about Pseudomonas spp. in Canine Otitis Externa.

Characterisation of luminal and triple-negative breast cancer with HER2 Low protein expression (2023)
Journal Article
Atallah, N. M., Haque, M., Quinn, C., Toss, M. S., Makhlouf, S., Ibrahim, A., Green, A. R., Alsaleem, M., Rutland, C. S., Allegrucci, C., Mongan, N. P., & Rakha, E. (2023). Characterisation of luminal and triple-negative breast cancer with HER2 Low protein expression. European Journal of Cancer, 195, Article 113371. https://doi.org/10.1016/j.ejca.2023.113371

Background: Breast cancer (BC) expressing low levels of human epidermal growth factor receptor 2 (HER2 Low) is an emerging category that needs further refining. This study aims to provide a comprehensive clinico-pathological and molecular profile of... Read More about Characterisation of luminal and triple-negative breast cancer with HER2 Low protein expression.

Evidence of personality-dependent plasticity in dairy calf movement behaviours derived from automated data collection (2023)
Journal Article
Occhiuto, F., Vázquez-Diosdado, J. A., King, A. J., & Kaler, J. (2023). Evidence of personality-dependent plasticity in dairy calf movement behaviours derived from automated data collection. Scientific Reports, 13, Article 18243. https://doi.org/10.1038/s41598-023-44957-z

Individual consistency in behaviour, known as animal personality, and behavioural plasticity in response to environmental changes are important factors shaping individual behaviour. Correlations between them, called personality-dependent plasticity,... Read More about Evidence of personality-dependent plasticity in dairy calf movement behaviours derived from automated data collection.