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Outputs (128)

Systematic Analysis of Breed, Methodological, and Geographical Impact on Equine Sperm Progressive Motility (2021)
Journal Article
Perrett, J., Harris, I. T., Maddock, C., Farnworth, M., Pyatt, A. Z., & Sumner, R. N. (2021). Systematic Analysis of Breed, Methodological, and Geographical Impact on Equine Sperm Progressive Motility. Animals, 11(11), Article 3088. https://doi.org/10.3390/ani11113088

Over the past five decades, there has been increasing evidence to indicate global declines in human semen quality. Parallel adverse trends measured in male animals indicate a potential environmental aetiology. This study evaluated the progressive mot... Read More about Systematic Analysis of Breed, Methodological, and Geographical Impact on Equine Sperm Progressive Motility.

Pentacyclic and hexacyclic cucurbitacins from Elaeocarpus petiolatus (2021)
Journal Article
Cho, E. S., Krishnan, P., Loh, H. S., Daly, J. M., Leong, C. O., Mai, C. W., Low, Y. Y., Yong, K. T., & Lim, K. H. (2022). Pentacyclic and hexacyclic cucurbitacins from Elaeocarpus petiolatus. Phytochemistry, 193, Article 112988. https://doi.org/10.1016/j.phytochem.2021.112988

Four undescribed cucurbitacins, designated as petiolaticins A–D, and four known cucurbitacins were isolated from the bark and leaves of Elaeocarpus petiolatus (Jack) Wall. Their chemical structures were elucidated based on detailed analyses of the NM... Read More about Pentacyclic and hexacyclic cucurbitacins from Elaeocarpus petiolatus.

A scoping review of the current evidence on treatment and outcomes following synovial sepsis (2021)
Journal Article
de Souza, T. C., Suthers, J. M., Busschers, E., Burford, J. H., & Freeman, S. L. (2022). A scoping review of the current evidence on treatment and outcomes following synovial sepsis. Equine Veterinary Journal, 54(3), 467-480. https://doi.org/10.1111/evj.13527

Background
Synovial sepsis is a frequent cause of morbidity and mortality in horses. Despite advances in diagnostics and treatments, persistent infection or chronic lameness can occur.

Objectives
To perform a scoping review to identify and evalu... Read More about A scoping review of the current evidence on treatment and outcomes following synovial sepsis.

Exercising D. melanogaster Modulates the Mitochondrial Proteome and Physiology. The Effect on Lifespan Depends upon Age and Sex (2021)
Journal Article
Ebanks, B., Wang, Y., Katyal, G., Sargent, C., Ingram, T. L., Bowman, A., Moisoi, N., & Chakrabarti, L. (2021). Exercising D. melanogaster Modulates the Mitochondrial Proteome and Physiology. The Effect on Lifespan Depends upon Age and Sex. International Journal of Molecular Sciences, 22(21), Article 11606. https://doi.org/10.3390/ijms222111606

Ageing is a major risk factor for many of the most prevalent diseases, including neurode-generative diseases, cancer, and heart disease. As the global population continues to age, behavioural interventions that can promote healthy ageing will improve... Read More about Exercising D. melanogaster Modulates the Mitochondrial Proteome and Physiology. The Effect on Lifespan Depends upon Age and Sex.

Biosecurity and the ornamental fish trade: A stakeholder perspective in England (2021)
Journal Article
Wood, L. E., Guilder, J., Brennan, M. L., Birland, N. J., Taleti, V., Stinton, N., Taylor, N. G. H., & Thrush, M. A. (2022). Biosecurity and the ornamental fish trade: A stakeholder perspective in England. Journal of Fish Biology, 100(2), 352-365. https://doi.org/10.1111/jfb.14928

The freshwater and marine ornamental fish industry is a primary route of hazard introduction and emergence, including aquatic animal diseases and non-native species. Prevention measures are key to reducing the risk of hazard incursion and establishme... Read More about Biosecurity and the ornamental fish trade: A stakeholder perspective in England.

Genetics of Asthma: Insights From Genome Wide Association Studies (2021)
Book Chapter
Cooper, R. M., Bingham, K., Portelli, M. A., & Sayers, I. (2022). Genetics of Asthma: Insights From Genome Wide Association Studies. In Encyclopedia of Respiratory Medicine (308-325). (Second Edition). Elsevier. https://doi.org/10.1016/B978-0-08-102723-3.00155-4

Asthma is a heterogeneous respiratory disease that can be influenced by genetic and environmental factors leading to disease susceptibility and progression. Genome-wide association studies (GWAS) of asthma have yielded replicated findings and identif... Read More about Genetics of Asthma: Insights From Genome Wide Association Studies.

Pharmacokinetics of paracetamol in the Thoroughbred horse following an oral multi-dose administration (2021)
Journal Article
Pesko, B., Habershon-Butcher, J., Muir, T., Gray, B., Taylor, P., Fenwick, S., Hincks, P., Scarth, J., & Paine, S. (2022). Pharmacokinetics of paracetamol in the Thoroughbred horse following an oral multi-dose administration. Journal of Veterinary Pharmacology and Therapeutics, 45(1), 54-62. https://doi.org/10.1111/jvp.13024

Paracetamol is a widely used, non-opioid analgesic and antipyretic drug. Scientific evidence suggests that it is an effective pain treatment in equine medicine. However, there is very little published information about the pharmacokinetics of the dru... Read More about Pharmacokinetics of paracetamol in the Thoroughbred horse following an oral multi-dose administration.

Comparative pathology of dog and human prostate cancer (2021)
Journal Article
Ryman-Tubb, T., Lothion-Roy, J. H., Metzler, V. M., Harris, A. E., Robinson, B. D., Rizvanov, A. A., Jeyapalan, J. N., James, V. H., England, G., Rutland, C. S., Persson, J. L., Kenner, L., Rubin, M. A., Mongan, N. P., & de Brot, S. (2022). Comparative pathology of dog and human prostate cancer. Veterinary Medicine and Science, 8(1), 110-120. https://doi.org/10.1002/vms3.642

Though relatively rare in dogs, prostate cancer (PCa) is the most common non-cutaneous cancer in men. Human and canine prostate glands share many functional, anatomical and physiological features. Due to these similarities, canine PCa has been propos... Read More about Comparative pathology of dog and human prostate cancer.

Extracellular vesicles, tumor growth, and the metastatic process (2021)
Book Chapter
Wesson, F., Brown, T. J., & James, V. (2022). Extracellular vesicles, tumor growth, and the metastatic process. In D. Heymann (Ed.), Bone Cancer: Bone Sarcomas and Bone Metastases - From Bench to Bedside (275-284). (3rd). Elsevier. https://doi.org/10.1016/B978-0-12-821666-8.00058-X

Extracellular vesicles (EVs) form an important part of cell-to-cell communication, with roles in both health and disease. Within the cancer setting, this heterogenous population of extracellular messengers can have both pro- and antitumorigenic prope... Read More about Extracellular vesicles, tumor growth, and the metastatic process.