Outputs (102)

Pathological findings in the pituitary glands of 201 dogs and cats (2018)
Journal Article
Polledo, L., Grinwis, G. C., Graham, P., Dunning, M., & Baiker, K. (2018). Pathological findings in the pituitary glands of 201 dogs and cats. Veterinary Pathology, 55(6), 880-888. https://doi.org/10.1177/0300985818784162

With the exception of classic functional adenomas in dogs and horses, pituitary lesions are infrequently described in the veterinary literature. Approximately 10% of pituitary glands from asymptomatic humans contain abnormalities but the equivalent p... Read More about Pathological findings in the pituitary glands of 201 dogs and cats.

Transcriptomic analysis reveals Toxoplasma gondii strain-specific differences in host cell response to dense granule protein GRA15 (2018)
Journal Article
Liu, Q., Gao, W.-W., Elsheikha, H. M., He, J.-J., Li, F.-C., Yang, W.-B., & Zhu, X.-Q. (2018). Transcriptomic analysis reveals Toxoplasma gondii strain-specific differences in host cell response to dense granule protein GRA15. Parasitology Research, 117(9), 2785–2793. https://doi.org/10.1007/s00436-018-5966-8

Growth and replication of the protozoan parasite Toxoplasma gondii within host cell entail the production of several effector proteins, which the parasite exploits for counteracting the host’s immune response. Despite considerable research to define... Read More about Transcriptomic analysis reveals Toxoplasma gondii strain-specific differences in host cell response to dense granule protein GRA15.

Key actors in driving behavioural change in relation to on-farm biosecurity; a Northern Ireland perspective (2018)
Journal Article
Lahuerta-Marin, A., Brennan, M., Finney, G., O’Hagan, M., & Jack, C. (2018). Key actors in driving behavioural change in relation to on-farm biosecurity; a Northern Ireland perspective. Irish Veterinary Journal, 71(1), Article 14. https://doi.org/10.1186/s13620-018-0125-1

Background: Agriculture and farming are valued contributors to local economy in Northern Ireland (NI). There is limited knowledge about farmers’ behaviours and attitudes towards disease biosecurity measures. As part of a larger project, a scenario-ba... Read More about Key actors in driving behavioural change in relation to on-farm biosecurity; a Northern Ireland perspective.

Toxocariasis: a silent threat with a progressive public health impact (2018)
Journal Article
Chen, J., Liu, Q., Liu, G.-H., Zheng, W.-B., Hong, S.-J., Sugiyama, H., Zhu, X.-Q., & Elsheikha, H. M. (2018). Toxocariasis: a silent threat with a progressive public health impact. Infectious Diseases of Poverty, 7(1), https://doi.org/10.1186/s40249-018-0437-0

Background: Toxocariasis is a neglected parasitic zoonosis that afflicts millions of the pediatric and adolescent populations worldwide, especially in impoverished communities. This disease is caused by infection with the larvae of Toxocara canis and... Read More about Toxocariasis: a silent threat with a progressive public health impact.

A novel recombinase polymerase amplification (RPA) assay for the rapid isothermal detection of Neospora caninum in aborted bovine fetuses (2018)
Journal Article
Tian, A., Elsheikha, H. M., Zhou, D.-H., Wu, Y.-D., Chen, M.-X., Wang, M., Chen, D., Zhang, X.-C., & Zhu, X.-Q. (2018). A novel recombinase polymerase amplification (RPA) assay for the rapid isothermal detection of Neospora caninum in aborted bovine fetuses. Veterinary Parasitology, 258, 24-29. https://doi.org/10.1016/j.vetpar.2018.06.004

The development of a method to rapidly diagnose Neospora caninum infection is highly desirable. Recombinase polymerase amplification (RPA), combined with lateral flow (LF) strips, is a novel approach to rapidly amplify and visualize DNA. We have deve... Read More about A novel recombinase polymerase amplification (RPA) assay for the rapid isothermal detection of Neospora caninum in aborted bovine fetuses.

A retrospective review of great ape cardiovascular disease epidemiology and pathology (2018)
Journal Article
Strong, V. J., Martin, M., Redrobe, S., White, K., & Baiker, K. (2018). A retrospective review of great ape cardiovascular disease epidemiology and pathology. International Zoo Yearbook, 52(1), 113-125. https://doi.org/10.1111/izy.12193

Cardiovascular disease is associated with significant mortality in zoo-housed great apes and yet little is know about its epidemiology and aetiopathogenesis, and therefore its diagnosis, treatment and prevention. In this retrospective study, the fre... Read More about A retrospective review of great ape cardiovascular disease epidemiology and pathology.

Variation in the reported management of canine prolapsed nictitans gland and feline herpetic keratitis (2018)
Journal Article
White, C. N., Jones, G., Baker, S., Dean, R. S., & Brennan, M. L. (2018). Variation in the reported management of canine prolapsed nictitans gland and feline herpetic keratitis. Veterinary Sciences, 5(2), Article 54. https://doi.org/10.3390/vetsci5020054

Treatment variation in medicine may be driven by evidence gaps, clinician factors, and patient preferences. Although well-documented in human medicine, variation in clinical management is relatively unexplored in veterinary practice. Clinical vignett... Read More about Variation in the reported management of canine prolapsed nictitans gland and feline herpetic keratitis.

The dog as an animal model for bladder and urethral urothelial carcinoma: comparative epidemiology and histology (2018)
Journal Article
de Brot, S., Robinson, B. D., Scase, T., Grau‑Roma, L., Wilkinson, E., Boorjian, S. A., Gardner, D. S., & Mongan, N. P. (2018). The dog as an animal model for bladder and urethral urothelial carcinoma: comparative epidemiology and histology. Oncology Letters, 16(2), https://doi.org/10.3892/ol.2018.8837

Despite the recent approval of several novel agents for patients with metastatic urothelial carcinoma (UC), survival in this setting remains poor. As such, continued investigation into novel therapeutic options remains warranted. Pre clinical develop... Read More about The dog as an animal model for bladder and urethral urothelial carcinoma: comparative epidemiology and histology.

Guidelines for consistent cardiovascular post-mortem examination, sampling and reporting of lesions in European zoo-housed great apes (2018)
Journal Article
Strong, V., Sheppard, M., Redrobe, S., & Baiker, K. (2018). Guidelines for consistent cardiovascular post-mortem examination, sampling and reporting of lesions in European zoo-housed great apes. International Zoo Yearbook, 52(1), 126-136. https://doi.org/10.1111/izy.12191

Inconsistencies and inadequacies in both the approach to post-mortem examination of the heart and the subsequent reporting of findings have been blamed for a lack of progression of understanding about great ape cardiovascular disease. In order to min... Read More about Guidelines for consistent cardiovascular post-mortem examination, sampling and reporting of lesions in European zoo-housed great apes.

Needle in a haystack? A comparison of eDNA metabarcoding and targeted qPCR for detection of the great crested newt (Triturus cristatus) (2018)
Journal Article
Harper, L. R., Lawson Handley, L., Hahn, C., Boonham, N., Rees, H. C., Gough, K. C., Lewis, E., Adams, I. P., Brotherton, P., Phillips, S., & Hänfling, B. (2018). Needle in a haystack? A comparison of eDNA metabarcoding and targeted qPCR for detection of the great crested newt (Triturus cristatus). Ecology and Evolution, 8(12), 6330-6341. https://doi.org/10.1002/ece3.4013

Environmental DNA (eDNA) analysis is a rapid, cost-effective, non-invasive biodiversity monitoring tool which utilises DNA left behind in the environment by organisms for species detection. The method is used as a species-specific survey tool for rar... Read More about Needle in a haystack? A comparison of eDNA metabarcoding and targeted qPCR for detection of the great crested newt (Triturus cristatus).