Outputs (139)

The influenza NS1 protein: what do we know in equine influenza virus pathogenesis? (2016)
Journal Article
Barba, M., & Daly, J. M. (2016). The influenza NS1 protein: what do we know in equine influenza virus pathogenesis?. Pathogens, 5(3), Article 57. https://doi.org/10.3390/pathogens5030057

Equine influenza virus remains a serious health and potential economic problem throughout most parts of the world, despite intensive vaccination programs in some horse populations. The influenza non-structural protein 1 (NS1) has multiple functions i... Read More about The influenza NS1 protein: what do we know in equine influenza virus pathogenesis?.

Targeted suppression of AR-V7 using PIP5K1α inhibitor overcomes enzalutamide resistance in prostate cancer cells (2016)
Journal Article
Sarwar, M., Semenas, J., Miftakhova, R., Simoulis, A., Robinson, B., Wingren, A. G., Mongan, N. P., Heery, D. M., Johnsson, H., Abrahamsson, P.-A., Dizeyi, N., Luo, J., & Persson, J. L. (2016). Targeted suppression of AR-V7 using PIP5K1α inhibitor overcomes enzalutamide resistance in prostate cancer cells. Oncotarget, 7(39), 63065-63081. https://doi.org/10.18632/oncotarget.11757

One mechanism of resistance of prostate cancer (PCa) to enzalutamide (MDV3100) treatment is the increased expression of AR variants lacking the ligand binding-domain, the best characterized of which is AR-V7. We have previously reported that Phosphat... Read More about Targeted suppression of AR-V7 using PIP5K1α inhibitor overcomes enzalutamide resistance in prostate cancer cells.

Ostertagia spp., rumen fluke and liver fluke single- and poly-infections in cattle: an abattoir study of prevalence and production impacts in England and Wales (2016)
Journal Article
Bellet, C., Green, M. J., Vickers, M., Forbes, A., Berry, J., & Kaler, J. (in press). Ostertagia spp., rumen fluke and liver fluke single- and poly-infections in cattle: an abattoir study of prevalence and production impacts in England and Wales. Preventive Veterinary Medicine, 132, https://doi.org/10.1016/j.prevetmed.2016.08.010

This study aims at investigating the occurrence, risk factors and production impacts on beef carcassparameters of three of the most important cattle helminth infections in England and Wales. Abomasa, reticulorumens and livers from healthy cattle were... Read More about Ostertagia spp., rumen fluke and liver fluke single- and poly-infections in cattle: an abattoir study of prevalence and production impacts in England and Wales.

Detection of a Yersinia pestisgene homologue in rodent samples (2016)
Journal Article
Giles, T. A., Greenwood, A. D., Tsangaras, K., Giles, T. C., Barrow, P. A., Hannant, D., Abu-Median, A.-B., & Yon, L. (2016). Detection of a Yersinia pestisgene homologue in rodent samples. PeerJ, 4, Article e2216. https://doi.org/10.7717/peerj.2216

A homologue to a widely used genetic marker, pla, for Yersinia pestis has been identified in tissue samples of two species of rat (Rattus rattus and Rattus norvegicus) and of mice (Mus musculus and Apodemus sylvaticus) using a microarray based platfo... Read More about Detection of a Yersinia pestisgene homologue in rodent samples.

‘Disperse abroad in the land’: the role of wildlife in the dissemination of antimicrobial resistance (2016)
Journal Article
Arnold, K. E., Williams, N. J., & Bennett, M. (2016). ‘Disperse abroad in the land’: the role of wildlife in the dissemination of antimicrobial resistance. Biology Letters, 12(8), Article 0137. https://doi.org/10.1098/rsbl.2016.0137

Antimicrobial resistance (AMR) has been detected in the microbiota of many wildlife species, including long-distance migrants. Inadequately treated wastes from humans and livestock dosed with antimicrobial drugs are often assumed to be the main sourc... Read More about ‘Disperse abroad in the land’: the role of wildlife in the dissemination of antimicrobial resistance.

Oxytocin versus carbetocin administered to cows after uncomplicated calvings and subsequent fertility (2016)
Journal Article
Robinson, N., & Brennan, M. L. (2016). Oxytocin versus carbetocin administered to cows after uncomplicated calvings and subsequent fertility. Veterinary Record, 179(7), https://doi.org/10.1136/vr.i3834

BestBETs for Vets are generated by the Centre for Evidence-based Veterinary Medicine at the University of Nottingham to help answer specific questions and assist in clinical decision making. Although evidence is often limited, they aim to find, prese... Read More about Oxytocin versus carbetocin administered to cows after uncomplicated calvings and subsequent fertility.

Mapping B-cell responses to Salmonella enterica serovars Typhimurium and Enteritidis in chickens for the discrimination of infected from vaccinated animals (2016)
Journal Article
Naqid, I. A., Owen, J. P., Maddison, B. C., Spiliotopoulos, A., Emes, R. D., Warry, A., Flynn, R. J., Martelli, F., Gosling, R. J., Davies, R. H., La Ragione, R. M., & Gough, K. C. (2016). Mapping B-cell responses to Salmonella enterica serovars Typhimurium and Enteritidis in chickens for the discrimination of infected from vaccinated animals. Scientific Reports, 6, Article 31186. https://doi.org/10.1038/srep31186

Serological surveillance and vaccination are important strategies for controlling infectious diseases of food production animals. However, the compatibility of these strategies is limited by a lack of assays capable of di erentiating infected from va... Read More about Mapping B-cell responses to Salmonella enterica serovars Typhimurium and Enteritidis in chickens for the discrimination of infected from vaccinated animals.

Environmental chemicals impact dog semen quality in vitro and may be associated with a temporal decline in sperm motility and increased cryptorchidism (2016)
Journal Article
Lea, R. G., Byers, A. S., Sumner, R. N., Rhind, S. M., Zhang, Z., Freeman, S. L., Moxon, R., Richardson, H. M., Green, M., Craigon, J., & England, G. C. (2016). Environmental chemicals impact dog semen quality in vitro and may be associated with a temporal decline in sperm motility and increased cryptorchidism. Scientific Reports, 6(1), Article 31281. https://doi.org/10.1038/srep31281

Adverse temporal trends in human semen quality and cryptorchidism in infants have been associated with exposure to environmental chemicals (ECs) during development. Here we report that a population of breeding dogs exhibit a 26 year (1988–2014) decli... Read More about Environmental chemicals impact dog semen quality in vitro and may be associated with a temporal decline in sperm motility and increased cryptorchidism.

Subacute ruminal acidosis reduces sperm quality in beef bulls (2016)
Journal Article
Callaghan, M., McAuliffe, P., Rodgers, R., Hernandez-Medrano, J., & Perry, V. (in press). Subacute ruminal acidosis reduces sperm quality in beef bulls. Journal of Animal Science, 94, https://doi.org/10.2527/jas.2015-0235

Breeding bulls are commonly fed high-energy diets, which may induce subacute ruminal acidosis (SARA). In this experiment, 8 Santa Gertrudis bulls (age 20 ± 6 mo) were used to evaluate the extent and duration of effects of SARA on semen quality and th... Read More about Subacute ruminal acidosis reduces sperm quality in beef bulls.

Transcriptomic analysis of mouse liver reveals a potential hepato-enteric pathogenic mechanism in acute Toxoplasma gondii infection (2016)
Journal Article
He, J.-J., Ma, J., Elsheikha, H. M., Song, H.-Q., Huang, S.-Y., & Zhu, X.-Q. (2016). Transcriptomic analysis of mouse liver reveals a potential hepato-enteric pathogenic mechanism in acute Toxoplasma gondii infection. Parasites and Vectors, 9(1), Article 427. https://doi.org/10.1186/s13071-016-1716-x

Background

Toxoplasma gondii is a worldwide spread pathogen which can infect all tissues of its host. The transcriptomic responses of infected brain and spleen have been reported. However, our knowledge of the global transcriptomic change in infec... Read More about Transcriptomic analysis of mouse liver reveals a potential hepato-enteric pathogenic mechanism in acute Toxoplasma gondii infection.