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Outputs (26)

Quantification of the effect of in utero events on lifetime resilience in dairy cows (2024)
Journal Article
Lewis, K., Shewbridge Carter, L., Bradley, A., Dewhurst, R., Forde, N., Hyde, R., Kaler, J., March, M. D., Mason, C., O'Grady, L., Strain, S., Thompson, J., & Green, M. (2024). Quantification of the effect of in utero events on lifetime resilience in dairy cows. Journal of Dairy Science, 107(7), 4616-4633. https://doi.org/10.3168/jds.2023-24215

Currently, the dairy industry is facing many challenges that could affect its sustainability, including climate change and public perception of the industry. As a result, interest is increasing in the concept of identifying resilient animals, those w... Read More about Quantification of the effect of in utero events on lifetime resilience in dairy cows.

Improvement of mammary gland health in 81 'sentinel herds' in England and Scotland between 2012 and 2021. (2023)
Journal Article
Leach, K. A., Holsey, H. J., Bradley, A. J., & Green, M. J. (2023). Improvement of mammary gland health in 81 'sentinel herds' in England and Scotland between 2012 and 2021. Veterinary Record, Article e3605. https://doi.org/10.1002/vetr.3605

Background: Achieving a reduction in mastitis in dairy cows is a common industry goal, but there is no recent peer-reviewed record of progress in the UK. Methods: A convenience sample of 125 herds in England and Scotland was recruited based on the qu... Read More about Improvement of mammary gland health in 81 'sentinel herds' in England and Scotland between 2012 and 2021..

Potential of ESBL-producing Escherichia coli selection in bovine feces after intramammary administration of first generation cephalosporins using in vitro experiments (2022)
Journal Article
Speksnijder, D. C., Hopman, N. E. M., Kusters, N. E., Timmerman, A., Swinkels, J. M., Penterman, P. A. A., Krömker, V., Bradley, A. J., Botteldoorn, N., Gehring, R., & Zomer, A. L. (2022). Potential of ESBL-producing Escherichia coli selection in bovine feces after intramammary administration of first generation cephalosporins using in vitro experiments. Scientific Reports, 12, Article 15083. https://doi.org/10.1038/s41598-022-15558-z

Selection and spread of Extended Spectrum Beta-Lactamase (ESBL) -producing Enterobacteriaceae within animal production systems and potential spillover to humans is a major concern. Intramammary treatment of dairy cows with first-generation cephalospo... Read More about Potential of ESBL-producing Escherichia coli selection in bovine feces after intramammary administration of first generation cephalosporins using in vitro experiments.

Mass spectrometry and machine learning for the accurate diagnosis of benzylpenicillin and multidrug resistance of Staphylococcus aureus in bovine mastitis (2021)
Journal Article
Esener, N., Guerra, A. M., Giebel, K., Lea, D., Green, M. J., Bradley, A. J., & Dottorini, T. (2021). Mass spectrometry and machine learning for the accurate diagnosis of benzylpenicillin and multidrug resistance of Staphylococcus aureus in bovine mastitis. PLoS Computational Biology, 17(6), Article e1009108. https://doi.org/10.1371/journal.pcbi.1009108

Staphylococcus aureus is a serious human and animal pathogen threat exhibiting extraordinary capacity for acquiring new antibiotic resistance traits in the pathogen population worldwide.

The development of fast, affordable and effective diagnostic... Read More about Mass spectrometry and machine learning for the accurate diagnosis of benzylpenicillin and multidrug resistance of Staphylococcus aureus in bovine mastitis.

Randomized controlled field trial comparing quarter and cow level selective dry cow treatment using the California Mastitis Test (2021)
Journal Article
Swinkels, J., Leach, K., Breen, J., Payne, B., White, V., Green, M., & Bradley, A. (2021). Randomized controlled field trial comparing quarter and cow level selective dry cow treatment using the California Mastitis Test. Journal of Dairy Science, 104(8), 9063-9081. https://doi.org/10.3168/jds.2020-19258

Selective use of antibiotic dry cow treatment can be implemented at the cow or quarter level, with the latter having the potential to further reduce antibiotic use. Our objective was to compare these 2 approaches in 6 herds in the United Kingdom in w... Read More about Randomized controlled field trial comparing quarter and cow level selective dry cow treatment using the California Mastitis Test.

Quantitative analysis of antimicrobial use on British dairy farms (2017)
Journal Article
Hyde, R. M., Remnant, J. G., Bradley, A. J., Breen, J. E., Hudson, C. D., Davies, P. L., Clarke, T., Critchell, Y., Hylands, M., Linton, E., Wood, E., & Green, M. J. (in press). Quantitative analysis of antimicrobial use on British dairy farms. Veterinary Record, 181(25), https://doi.org/10.1136/vr.104614

Antimicrobial resistance has been reported to represent a growing threat to both human and animal health, and concerns have been raised around levels of antimicrobial usage (AMU) within the livestock industry. To provide a benchmark for dairy cattle... Read More about Quantitative analysis of antimicrobial use on British dairy farms.

The impact of dairy cows' bedding material and its microbial content on the quality and safety of milk: a cross sectional study of UK farms (2017)
Journal Article
Bradley, A. J., Leach, K. A., Green, M. J., Gibbons, J., Ohnstad, I. C., Black, D. H., Payne, B., Prout, V. E., & Breen, J. E. (in press). The impact of dairy cows' bedding material and its microbial content on the quality and safety of milk: a cross sectional study of UK farms. International Journal of Food Microbiology, https://doi.org/10.1016/j.ijfoodmicro.2017.12.022

The introduction of bedding dairy cows on recycled manure solids (RMS) in the UK led to concern by competent authorities that there could be an increased, unacceptable risk to animal and human health. A cross-sectional study was designed to evaluate... Read More about The impact of dairy cows' bedding material and its microbial content on the quality and safety of milk: a cross sectional study of UK farms.

Factors affecting the cost-effectiveness of on-farm culture prior to the treatment of clinical mastitis in dairy cows (2017)
Journal Article
Down, P., Bradley, A. J., Breen, J., & Green, M. J. (2017). Factors affecting the cost-effectiveness of on-farm culture prior to the treatment of clinical mastitis in dairy cows. Preventive Veterinary Medicine, 145, https://doi.org/10.1016/j.prevetmed.2017.07.006

The objective of this study was to use probabilistic sensitivity analysis to evaluate the cost-effectiveness of using an on-farm culture (OFC) approach to the treatment of clinical mastitis in dairy cows and compare this to a ‘standard’ treatment app... Read More about Factors affecting the cost-effectiveness of on-farm culture prior to the treatment of clinical mastitis in dairy cows.

Prediction of Streptococcus uberis clinical mastitis risk using Matrix-assisted laser desorption ionization time of flight mass spectrometry (MALDI-TOF MS) in dairy herds (2017)
Journal Article
Archer, S. C., Bradley, A. J., Cooper, S., Davies, P., & Green, M. J. (2017). Prediction of Streptococcus uberis clinical mastitis risk using Matrix-assisted laser desorption ionization time of flight mass spectrometry (MALDI-TOF MS) in dairy herds. Preventive Veterinary Medicine, 144, https://doi.org/10.1016/j.prevetmed.2017.05.015

The purpose of this study was to evaluate whether the risk of Streptococcus uberis clinical mastitis at cow level could be predicted from the historical presence of specific strains of S. uberis on dairy farms. Matrix-assisted laser desorption ioniza... Read More about Prediction of Streptococcus uberis clinical mastitis risk using Matrix-assisted laser desorption ionization time of flight mass spectrometry (MALDI-TOF MS) in dairy herds.