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Novel perspectives of sodium handling in type 2 diabetes mellitus (2022)
Journal Article
Hanson, P., Arkill, K. P., Merry, C. L., Hussain, M. S., Meersmann, T., Randeva, H. S., …Barber, T. M. (2022). Novel perspectives of sodium handling in type 2 diabetes mellitus. Expert Review of Endocrinology and Metabolism, 17(4), 333-341. https://doi.org/10.1080/17446651.2022.2092094

Introduction: As a key regulator of body water, sodium homeostasis forms an essential component of human physiology. Type 2 Diabetes Mellitus (T2D)-associated sodium overload stems from chronic renal retention of sodium, contributing toward the devel... Read More about Novel perspectives of sodium handling in type 2 diabetes mellitus.

Sodium in the dermis colocates to glycosaminoglycan scaffold, with diminishment in type 2 diabetes mellitus (2021)
Journal Article
Hanson, P., Philp, C. J., Randeva, H. S., James, S., O’Hare, J. P., Meersmann, T., …Barber, T. M. (2021). Sodium in the dermis colocates to glycosaminoglycan scaffold, with diminishment in type 2 diabetes mellitus. JCI insight, 6(12), Article e145470. https://doi.org/10.1172/jci.insight.145470

BACKGROUND. Dietary sodium intake mismatches urinary sodium excretion over prolonged periods. Our aims were to localize and quantify electrostatically bound sodium within human skin using triple-quantum-filtered (TQF) protocols for MRI and magnetic r... Read More about Sodium in the dermis colocates to glycosaminoglycan scaffold, with diminishment in type 2 diabetes mellitus.

Hyperpolarised xenon MRI and time-resolved X-ray computed tomography studies of structure-transport relationships in hierarchical porous media (2020)
Journal Article
Hill-Casey, F., Hotchkiss, T., Hardstone, K. A., Hitchcock, I., Novak, V., Schlepütz, C. M., …Rigby, S. P. (2021). Hyperpolarised xenon MRI and time-resolved X-ray computed tomography studies of structure-transport relationships in hierarchical porous media. Chemical Engineering Journal, 405, Article 126750. https://doi.org/10.1016/j.cej.2020.126750

© 2020 Elsevier B.V. Catalysed diesel particulate filter (DPF) monoliths are hierarchical porous solids, as demonstrated by mercury porosimetry. Establishing structure-transport relationships, including assessing the general accessibility of the cata... Read More about Hyperpolarised xenon MRI and time-resolved X-ray computed tomography studies of structure-transport relationships in hierarchical porous media.

Structural and chemical heterogeneity in ancient glass probed using gas overcondensation, X-ray tomography, and solid-state NMR (2020)
Journal Article
Rigby, S. P., Stevens, L., Meersmann, T., Pavlovskaya, G. E., Rees, G. J., Henderson, J., …Fletcher, R. S. (2020). Structural and chemical heterogeneity in ancient glass probed using gas overcondensation, X-ray tomography, and solid-state NMR. Materials Characterization, 167, Article 110467. https://doi.org/10.1016/j.matchar.2020.110467

Rare ancient glasses have complex, multi-scale structures requiring more sophisticated and non-destructive pore characterisation techniques than usual. Homotattic patch models for nitrogen adsorption gave better fits to the isotherm data, more accura... Read More about Structural and chemical heterogeneity in ancient glass probed using gas overcondensation, X-ray tomography, and solid-state NMR.

Operando visualisation of battery chemistry in a sodium-ion battery by 23Na magnetic resonance imaging (2020)
Journal Article
Kendrick, E., Bray, J. M., Doswell, C. L., Pavlovskaya, G. E., Chen, L., Kishore, B., …Britton, M. M. (2020). Operando visualisation of battery chemistry in a sodium-ion battery by 23Na magnetic resonance imaging. Nature Communications, 11(1), Article 2083. https://doi.org/10.1038/s41467-020-15938-x

© 2020, The Author(s). Sodium-ion batteries are a promising battery technology for their cost and sustainability. This has led to increasing interest in the development of new sodium-ion batteries and new analytical methods to non-invasively, directl... Read More about Operando visualisation of battery chemistry in a sodium-ion battery by 23Na magnetic resonance imaging.

Accelerated 19F·MRI Detection of Matrix Metalloproteinase-2/-9 through Responsive Deactivation of Paramagnetic Relaxation Enhancement (2019)
Journal Article
Faas, H. M., Krupa, J. L., Taylor, A. J., Zamberlan, F., Philp, C. J., Williams, H. E., …Meersmann, T. (2019). Accelerated 19F·MRI Detection of Matrix Metalloproteinase-2/-9 through Responsive Deactivation of Paramagnetic Relaxation Enhancement. Contrast Media and Molecular Imaging, 2019, 1-13. https://doi.org/10.1155/2019/4826520

Paramagnetic gadolinium ions (Gd III), complexed within DOTA-based chelates, have become useful tools to increase the magnetic resonance imaging (MRI) contrast in tissues of interest. Recently, " on/off " probes serving as 19 F·MRI biosensor for targ... Read More about Accelerated 19F·MRI Detection of Matrix Metalloproteinase-2/-9 through Responsive Deactivation of Paramagnetic Relaxation Enhancement.

Magnetic resonance imaging on sodium nuclei: potential medical applications of 23Na MRI (2018)
Journal Article
Sadykhov, E., Pirogov, Y., Anisimov, N., Gulyaev, M., Pavlovskaya, G., Meersmann, T., …Fomina, D. (2018). Magnetic resonance imaging on sodium nuclei: potential medical applications of 23Na MRI. Applied Magnetic Resonance, 925-957. https://doi.org/10.1007/s00723-018-1045-7

Sodium is a key element in a living organism. The increase of its concentration is an indicator of many pathological conditions. 23Na magnetic resonance imaging (MRI) is a quantitative method that allows to determine the sodium content in tissues and... Read More about Magnetic resonance imaging on sodium nuclei: potential medical applications of 23Na MRI.

Fluid flow in a porous medium with transverse permeability discontinuity (2018)
Journal Article
Pavlovskaya, G. E., Meersmann, T., Jin, C., & Rigby, S. P. (2018). Fluid flow in a porous medium with transverse permeability discontinuity. Physical Review Fluids, 3(4), https://doi.org/10.1103/PhysRevFluids.3.044102

Magnetic Resonance Imaging (MRI) velocimetry methods were used to study fully developed axially symmetric fluid flow in a model porous medium of cylindrical symmetry with a transverse permeability discontinuity. Spatial mapping of fluid ow resulted i... Read More about Fluid flow in a porous medium with transverse permeability discontinuity.

Probe-Specific Procedure to Estimate Sensitivity and Detection Limits for 19F Magnetic Resonance Imaging (2016)
Journal Article
Faas, H., Taylor, A. J., Granwehr, J., Lesbats, C., Krupa, J. L., Six, J. S., …Meersmann, T. (2016). Probe-Specific Procedure to Estimate Sensitivity and Detection Limits for 19F Magnetic Resonance Imaging. PLoS ONE, 11(10), e0163704. https://doi.org/10.1371/journal.pone.0163704

© 2016 Taylor et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are cre... Read More about Probe-Specific Procedure to Estimate Sensitivity and Detection Limits for 19F Magnetic Resonance Imaging.