Skip to main content

Research Repository

Advanced Search

Outputs (831)

Molecular sensing with hyperpolarized 129Xe using switchable chemical exchange relaxation transfer (2015)
Journal Article
Zamberlan, F., Lesbats, C., Rogers, N. J., Krupa, J. L., Pavlovskaya, G. E., Thomas, N. R., Faas, H., & Meersmann, T. (2015). Molecular sensing with hyperpolarized 129Xe using switchable chemical exchange relaxation transfer. ChemPhysChem, 16(11), https://doi.org/10.1002/cphc.201500367

A new approach for hyperpolarized 129Xe molecular sensors is explored using paramagnetic relaxation agents that can be deactivated upon chemical or enzymatic reaction with an analyte. Cryptophane encapsulated 129Xe within the vicinity of the paramagn... Read More about Molecular sensing with hyperpolarized 129Xe using switchable chemical exchange relaxation transfer.

Symptoms into words: how medical patients talk about fatigue (2015)
Book Chapter
Standen, P., Ward, C. D., Saunders, L., & Beer, C. (2015). Symptoms into words: how medical patients talk about fatigue. In C. D. Ward (Ed.), Meanings of ME: interpersonal and social dimensions of chronic fatigue (67-85). Palgrave Macmillan. https://doi.org/10.1057/9781137467324_7

Fatigue, which is the central symptom of CFS/ME, is notoriously difficult to define. We describe an investigation in which we raise two questions. First, does the way people use fatigue-related language reflect distinctive patterns? Second, is there... Read More about Symptoms into words: how medical patients talk about fatigue.

Does release of antimicrobial agents from impregnated external ventricular drainage catheters affect the diagnosis of ventriculitis? (2015)
Journal Article
Bayston, R., Ashraf, W., & Ortori, C. (2015). Does release of antimicrobial agents from impregnated external ventricular drainage catheters affect the diagnosis of ventriculitis?. Journal of Neurosurgery, 124(2), https://doi.org/10.3171/2014.12.JNS141900

OBJECT

Recently concern has arisen over the effect of released antimicrobial agents from antibiotic-impregnated external ventricular drainage (EVD) catheters on the reliability of CSF culture for diagnosis of ventriculitis. The authors designed a... Read More about Does release of antimicrobial agents from impregnated external ventricular drainage catheters affect the diagnosis of ventriculitis?.

Discovery of a Novel Polymer for Human Pluripotent Stem Cell Expansion and Multilineage Differentiation (2015)
Journal Article
Smith, J. G. W., Celiz, A. D., Smith, J. G., Patel, A. K., Hook, A. L., Rajamohan, D., George, V. T., Flatt, L., Patel, M. J., Epa, V. C., Singh, T., Langer, R., Anderson, D. G., Allen, N. D., Hay, D. C., Winkler, D. A., Barrett, D. A., Davies, M. C., Young, L. E., Denning, C., & Alexander, M. R. (2015). Discovery of a Novel Polymer for Human Pluripotent Stem Cell Expansion and Multilineage Differentiation. Advanced Materials, 27(27), 4006-4012. https://doi.org/10.1002/adma.201501351

© 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. A scalable and cost-effective synthetic polymer substrate that supports robust expansion and subsequent multilineage differentiation of human pluripotent stem cells (hPSCs) with defined commercial... Read More about Discovery of a Novel Polymer for Human Pluripotent Stem Cell Expansion and Multilineage Differentiation.

Reproducibility of graph-theoretic brain network metrics: a systematic review (2015)
Journal Article
Welton, T., Kent, D., Auer, D. P., & Dineen, R. A. (2015). Reproducibility of graph-theoretic brain network metrics: a systematic review. Brain Connectivity, 5(4), 193-202. https://doi.org/10.1089/brain.2014.0313

This systematic review aimed to assess the reproducibility of graph-theoretic brain network metrics. Primary research studies of test-retest reliability conducted on healthy human subjects were included that quantified test-retest reliability using e... Read More about Reproducibility of graph-theoretic brain network metrics: a systematic review.

Endothelial cell loss following tissue harvesting by pneumodissection for endothelial keratoplasty: an ex vivo study. (2015)
Journal Article
SL, A., A, G., LE, S., MS, E., A, A., & HS, D. (2015). Endothelial cell loss following tissue harvesting by pneumodissection for endothelial keratoplasty: an ex vivo study. British Journal of Ophthalmology, 99(5), 710-713. https://doi.org/10.1136/bjophthalmol-2014-306560

Aims
To study ex vivo the difference in endothelial cell density (ECD) in tissue harvested by pneumodissection for pre-Descemet's endothelial keratoplasty (PDEK) and Descemet's membrane endothelial keratoplasty (DMEK).

Methods
Tissue for PDEK... Read More about Endothelial cell loss following tissue harvesting by pneumodissection for endothelial keratoplasty: an ex vivo study..

Auditory training can improve working memory, attention, and communication in adverse conditions for adults with hearing loss (2015)
Journal Article
Ferguson, M. A., & Henshaw, H. (2015). Auditory training can improve working memory, attention, and communication in adverse conditions for adults with hearing loss. Frontiers in Psychology, 6, Article 556. https://doi.org/10.3389/fpsyg.2015.00556

Auditory training (AT) helps compensate for degradation in the auditory signal. A series of three high-quality training studies are discussed, which include, (i) a randomized controlled trial (RCT) of phoneme discrimination in quiet that trained adul... Read More about Auditory training can improve working memory, attention, and communication in adverse conditions for adults with hearing loss.

Practical dyspnea assessment: relationship between the 0–10 numerical rating scale and the four-level categorical verbal descriptor scale of dyspnea intensity (2015)
Journal Article
Wysham, N. G., Miriovsky, B. J., Currow, D. C., Herndon, J. E., Samsa, G. P., Wilcock, A., & Abernethy, A. P. (in press). Practical dyspnea assessment: relationship between the 0–10 numerical rating scale and the four-level categorical verbal descriptor scale of dyspnea intensity. Journal of Pain and Symptom Management, 50(4), https://doi.org/10.1016/j.jpainsymman.2015.04.015

Context—Measurement of dyspnea is important for clinical care and research.
Objectives—To characterize the relationship between the 0–10 Numerical Rating Scale (NRS) and four-level categorical Verbal Descriptor Scale (VDS) for dyspnea assessment.
M... Read More about Practical dyspnea assessment: relationship between the 0–10 numerical rating scale and the four-level categorical verbal descriptor scale of dyspnea intensity.

TLR2 Stimulation Regulates the Balance between Regulatory T Cell and Th17 Function: A Novel Mechanism of Reduced Regulatory T Cell Function in Multiple Sclerosis (2015)
Journal Article
Nyirenda, M. H., Morandi, E., Vinkemeier, U., Constantin-Teodosiu, D., Drinkwater, S., Mee, M., King, L., Podda, G., Zhang, G.-X., Ghaemmaghami, A., Constantinescu, C. S., Bar-Or, A., & Gran, B. (2015). TLR2 Stimulation Regulates the Balance between Regulatory T Cell and Th17 Function: A Novel Mechanism of Reduced Regulatory T Cell Function in Multiple Sclerosis. Journal of Immunology, 194(12), 5761-5774. https://doi.org/10.4049/%E2%80%8Bjimmunol.1400472

CD4+CD25hi FOXP3+ regulatory T cells (Tregs) maintain tolerance to self-Ags. Their defective function is involved in the pathogenesis of multiple sclerosis (MS), an inflammatory demyelinating disease of the CNS. However, the mechanisms of such defect... Read More about TLR2 Stimulation Regulates the Balance between Regulatory T Cell and Th17 Function: A Novel Mechanism of Reduced Regulatory T Cell Function in Multiple Sclerosis.